Repligen Corporation (RGEN) Key Metrics

NASDAQ: RGENValuation, returns, debt and efficiency ratios over 10 years.

RGEN valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$11.14B
Enterprise value
$10.29B
P/E (TTM)
240.3
10-yr median 144.3
Forward P/E
67.1
PEG ratio
1.84
Price / sales
14.2
10-yr median 12.6
Price / book
4.9
10-yr median 5.1
EV / EBITDA
53.6
10-yr median 64.5
Dividend yield
—
Beta
1.08

RGEN key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

RGEN valuation Price multiples at each fiscal year-end price.

P/E ratio
189.6
2025 · hover or tap a bar for each year
2016: 90.0 (−11.5%)2017: 50.1 (−44.3%)2018: 144.3 (+188.1%)2019: 212.6 (+47.3%)2020: 172.3 (−18.9%)2021: 118.2 (−31.4%)2022: 52.3 (−55.7%)2023: 243.8 (+366.1%)2025: 189.6
20162025
Price / sales−1.1%
12.6
2025 · hover or tap a bar for each year
2016: 10.1 (−11.6%)2017: 10.1 (0.0%)2018: 12.4 (+22.9%)2019: 16.8 (+36.3%)2020: 28.2 (+67.4%)2021: 22.6 (−19.8%)2022: 12.1 (−46.3%)2023: 15.9 (+30.8%)2024: 12.7 (−20.0%)2025: 12.6 (−1.1%)
20162025
Price / book+7.8%
4.4
2025 · hover or tap a bar for each year
2016: 6.2 (−19.5%)2018: 3.92019: 4.3 (+10.2%)2020: 6.8 (+57.2%)2021: 8.7 (+28.3%)2022: 5.1 (−41.3%)2023: 5.1 (+1.0%)2024: 4.1 (−20.6%)2025: 4.4 (+7.8%)
20162025
EV / EBITDA−49.4%
50.4
2025 · hover or tap a bar for each year
2016: 40.9 (+4.8%)2017: 55.6 (+36.0%)2018: 55.3 (−0.7%)2019: 76.1 (+37.8%)2020: 100.4 (+32.0%)2021: 73.4 (−26.9%)2022: 34.4 (−53.2%)2023: 81.2 (+136.5%)2024: 99.4 (+22.4%)2025: 50.4 (−49.4%)
20162025
Price / free cash flow+74.7%
98.7
2025 · hover or tap a bar for each year
2016: 328.8 (+330.1%)2017: 118.4 (−64.0%)2018: 128.0 (+8.1%)2019: 103.3 (−19.3%)2020: 284.6 (+175.6%)2021: 292.1 (+2.6%)2022: 251.1 (−14.0%)2023: 135.3 (−46.1%)2024: 56.5 (−58.2%)2025: 98.7 (+74.7%)
20162025
Free cash flow yield−0.8 pts
1.0%
2025 · hover or tap a bar for each year
2016: 0.3% (−1.0 pts)2017: 0.8% (+0.5 pts)2018: 0.8% (−0.1 pts)2019: 1.0% (+0.2 pts)2020: 0.4% (−0.6 pts)2021: 0.3% (0.0 pts)2022: 0.4% (+0.1 pts)2023: 0.7% (+0.3 pts)2024: 1.8% (+1.0 pts)2025: 1.0% (−0.8 pts)
20162025

RGEN valuation history

Fiscal year-endToday10-year median

RGEN returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

RGEN debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

RGEN cash returned to shareholders

DividendsBuybacksFree cash flow

RGEN price vs earnings per share

Share price at year-endEPS (right axis)

RGEN key metrics

2016–2025
Repligen Corporation key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$9.27B$8.05B$10.14B$9.73B$15.17B$10.33B$4.55B$2.40B$1.42B$1.05B
Enterprise value$9.19B$7.98B$10.10B$9.53B$14.93B$9.89B$4.29B$2.31B$1.35B$1.00B
P/E ratio189.6—243.852.3118.2172.3212.6144.350.190.0
Price / sales12.612.715.912.122.628.216.812.410.110.1
Price / book4.44.15.15.18.76.84.33.9—6.2
Price / free cash flow98.756.5135.3251.1292.1284.6103.3128.0118.4328.8
Price / operating cash flow78.945.989.056.5127.4164.967.773.281.4139.7
EV / sales12.412.615.811.922.327.015.911.99.59.6
EV / EBITDA50.499.481.234.473.4100.476.155.355.640.9
EV / free cash flow97.956.0134.8245.9287.5272.597.3123.2112.2314.3
Earnings yield0.5%−0.3%0.4%1.9%0.8%0.6%0.5%0.7%2.0%1.1%
Free cash flow yield1.0%1.8%0.7%0.4%0.3%0.4%1.0%0.8%0.8%0.3%
Dividend yield——5.6%0.2%0.0%—0.0%—0.0%0.0%
Shareholder yield (dividends + buybacks)0.0%0.2%5.7%0.3%0.0%0.0%0.0%0.0%0.0%0.0%
Share price at fiscal year-end$163.86$143.94$179.80$169.31$264.84$191.63$92.50$52.74$36.28$30.82
Per share
Revenue per share$13.05$11.34$11.33$13.95$11.71$6.80$5.49$4.27$3.61$3.07
Earnings per share$0.86−$0.46$0.74$3.24$2.24$1.11$0.44$0.37$0.72$0.34
Operating cash flow per share$2.08$3.14$2.02$3.00$2.08$1.16$1.37$0.72$0.45$0.22
Free cash flow per share$1.66$2.55$1.33$0.67$0.91$0.67$0.90$0.41$0.31$0.09
Cash per share$13.57$13.54$13.33$10.86$10.54$13.31$10.74$4.26$4.44$4.16
Book value per share$37.24$35.27$34.96$33.26$30.56$28.37$21.54$13.54−$0.80$4.95
Tangible book value per share$10.71$9.72$10.35$12.09$9.65$11.57$7.70$3.37−$12.86$2.33
Dividends per share——$10.03$0.30$0.05—$0.01—$0.00$0.00
Capex per share$0.42$0.59$0.69$2.32$1.17$0.49$0.47$0.31$0.14$0.13
Debt per share$12.20$12.27$12.63$7.36$6.39$5.11$5.35$2.28$2.54$2.79
Shares outstanding56.6M55.9M56.4M57.5M57.3M53.9M49.2M45.5M39.1M34.1M
Change in shares outstanding+1.1%−0.8%−1.9%+0.3%+6.3%+9.5%+8.2%+16.1%+14.8%+1.6%
Returns & profitability
Return on equity (ROE)2.4%−1.3%2.1%10.2%7.8%4.6%2.6%5.7%—8.0%
Return on invested capital (ROIC)2.4%−1.4%1.9%11.8%10.8%8.6%5.0%9.6%—18.6%
Return on assets (ROA)1.7%−0.9%1.6%7.6%6.0%3.6%2.8%12.8%13.9%5.4%
Return on tangible assets3.4%−1.8%2.9%14.1%11.1%6.0%3.0%——5.9%
Free cash flow margin12.7%22.5%11.7%4.8%7.7%9.9%16.3%9.7%8.5%3.1%
Income quality (OCF / net income)2.40—2.740.930.931.053.141.970.620.64
Financial health
Total debt$689.9M$686.2M$711.8M$423.0M$366.1M$275.4M$263.3M$103.5M$99.2M$95.3M
Cash & short-term investments$767.6M$757.4M$751.3M$623.8M$603.8M$717.3M$528.4M$193.8M$173.8M$141.8M
Net debt−$77.7M−$71.1M−$39.5M−$200.8M−$237.8M−$441.9M−$265.1M−$90.3M−$74.5M−$46.5M
Debt / equity0.330.350.360.220.210.180.250.17—0.56
Debt / assets0.230.240.250.170.160.140.190.740.820.33
Net debt / EBITDA−0.43−0.89−0.32−0.72−1.17−4.49−4.71−2.16−3.08−1.89
Current ratio8.378.417.022.472.482.8313.282.129.638.74
Quick ratio7.127.285.751.881.992.5312.151.808.087.57
Interest coverage2.6-1.65.475.513.26.74.33.92.24.2
Working capital$1.00B$939.3M$952.9M$593.9M$556.4M$583.4M$593.5M$145.9M$217.6M$163.1M
Invested capital$2.03B$1.90B$1.93B$1.71B$1.51B$1.09B$794.7M$525.2M−$106.0M$122.3M
Tangible asset value$605.6M$543.8M$583.6M$694.6M$552.4M$623.7M$378.8M−$481.8M−$503.6M$79.4M
Net current asset value$293.8M$209.1M$257.8M$377.2M$323.4M$528.6M$301.5M$116.7M$90.9M$64.0M
Graham number$26.91—$24.09$49.21$39.25$26.64$14.52$10.55—$6.18
Graham net-net per share$2.27$1.30$1.64$3.64$3.07$8.25$5.04$1.82$1.59$1.35
Capital allocation
Dividends paid——$565.7M$17.0M$2.9M—$490,000—$0$0
Share buybacks (net)$0$14.4M$14.4M$17.0M$2.9M$10,000$490,000$0$0$0
Dividend payout ratio———9.2%2.3%—2.3%—0.0%0.0%
Dividends + buybacks / free cash flow0.0%10.1%774.1%87.9%11.2%0.0%2.2%0.0%0.0%0.0%
Capex / revenue3.2%5.2%6.1%16.6%10.0%7.2%8.6%7.2%3.9%4.1%
Capex / operating cash flow20.0%18.8%34.2%77.5%56.4%42.1%34.4%42.8%31.3%57.5%
Capex / depreciation0.240.380.572.341.740.971.110.890.520.81
Stock-based compensation / revenue4.4%7.6%4.0%3.4%4.1%4.6%4.8%5.3%4.8%4.4%
R&D / revenue7.3%6.8%6.7%5.5%5.1%5.4%7.2%8.1%6.1%7.0%
SG&A / revenue39.4%41.5%33.5%26.9%27.4%32.7%35.4%34.2%36.5%29.5%
Efficiency
Days sales outstanding72.474.368.753.251.457.353.659.756.648.0
Days of inventory on hand146.4175.1226.8223.1182.7159.1134.2172.6173.4165.4
Days payables outstanding29.026.224.333.634.730.030.337.733.645.6
Cash conversion cycle (days)189.8223.2271.2242.7199.4186.4157.6194.5196.4167.7
Receivables turnover5.044.915.316.867.106.376.816.116.457.60
Payables turnover12.5713.9215.0510.8510.5212.1512.059.6710.868.00
Inventory turnover2.492.081.611.642.002.292.722.122.112.21
Asset turnover0.260.220.240.330.310.220.351.490.690.48
Average receivables$146.4M$129.1M$120.2M$116.8M$94.4M$57.5M$39.7M$31.7M$21.9M$13.8M
Average payables$31.1M$25.8M$23.6M$31.9M$26.5M$14.2M$11.0M$8.9M$6.2M$5.9M
Average inventory$156.7M$172.6M$220.3M$211.4M$139.8M$74.9M$48.5M$40.6M$31.9M$21.3M
Intangibles / total assets50.9%50.5%49.1%48.0%50.8%47.6%48.6%331.4%392.1%30.9%

Computed from RGEN's annual financial statements (latest annual report filed February 26, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

RGEN valuation and financial ratios

At the end of fiscal 2025 (December 31, 2025), Repligen traded at 189.6 times earnings, against a 10-year median of 144.3. Based on the latest twelve months, the trailing P/E is 240.3 and the forward P/E is 67.1. Repligen earned a return on equity of 2.4% and a return on invested capital of 2.4% in fiscal 2025. It ended the year with $689.9 million of debt and $767.6 million in cash and short-term investments, a net cash position of $77.7 million. The share count rose 65.9% from 34.1M to 56.6M over 9 years.

See the RGEN income statement, the RGEN chart for price history, or the RGEN stock overview for the latest quote and news.

RGEN key metrics FAQ

What is Repligen's P/E ratio?

Repligen's trailing P/E ratio is 240.3 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 67.1. At the end of fiscal 2025 it was 189.6, compared with a 10-year median of 144.3.

What is Repligen's EV/EBITDA?

Repligen's enterprise value was 50.4 times EBITDA at the end of fiscal 2025 (enterprise value $9.2 billion, EBITDA $182.5 million); the current EV/EBITDA is 53.6.

What is Repligen's return on equity?

Repligen's return on equity (ROE) was 2.4% in fiscal 2025: net income of $48.9 million on average shareholders' equity of $2.0 billion.

What is Repligen's ROIC?

Repligen's return on invested capital was 2.4% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Repligen have?

Repligen had total debt of $689.9 million at the end of fiscal 2025, a debt-to-equity ratio of 0.33 and more cash than debt.

What is Repligen's free cash flow yield?

Repligen generated $93.9 million of free cash flow in fiscal 2025, a free cash flow yield of 1.0% on its market value at year-end ($9.3 billion).

What is Repligen's current ratio?

Repligen's current ratio was 8.37 at the end of fiscal 2025: current assets were 8.37 times current liabilities.

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