Ironwood Pharmaceuticals, Inc. (IRWD) Key Metrics

NASDAQ: IRWDValuation, returns, debt and efficiency ratios over 10 years.

IRWD valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$578.3M
Enterprise value
$1.02B
P/E (TTM)
4.5
10-yr median 21.1
Forward P/E
12.3
PEG ratio
—
Price / sales
1.5
10-yr median 4.7
Price / book
2.6
10-yr median 28.0
EV / EBITDA
4.2
10-yr median 12.2
Dividend yield
—
Beta
0.22

IRWD key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

IRWD valuation Price multiples at each fiscal year-end price.

P/E ratio−96.9%
24.9
2025 · hover or tap a bar for each year
2019: 96.62020: 17.2 (−82.2%)2021: 3.6 (−78.9%)2022: 13.2 (+263.5%)2024: 805.92025: 24.9 (−96.9%)
20162025
Price / sales+0.2%
2.0
2025 · hover or tap a bar for each year
2016: 6.8 (−26.1%)2017: 6.3 (−8.1%)2018: 3.8 (−39.1%)2019: 4.8 (+27.0%)2020: 4.7 (−3.1%)2021: 4.6 (−1.4%)2022: 5.6 (+21.3%)2023: 4.0 (−28.6%)2024: 2.0 (−49.8%)2025: 2.0 (+0.2%)
20162025
EV / EBITDA−24.9%
9.4
2025 · hover or tap a bar for each year
2019: 18.12020: 13.5 (−25.4%)2021: 7.6 (−43.9%)2022: 7.9 (+4.3%)2023: 12.2 (+53.8%)2024: 12.5 (+2.6%)2025: 9.4 (−24.9%)
20162025
Price / free cash flow−31.2%
4.7
2025 · hover or tap a bar for each year
2019: 587.32020: 11.0 (−98.1%)2021: 7.3 (−33.1%)2022: 8.4 (+15.1%)2023: 9.7 (+15.1%)2024: 6.9 (−29.4%)2025: 4.7 (−31.2%)
20162025
Free cash flow yield+6.6 pts
21.2%
2025 · hover or tap a bar for each year
2016: −6.9% (+1.1 pts)2017: −5.6% (+1.4 pts)2018: −6.0% (−0.5 pts)2019: 0.2% (+6.2 pts)2020: 9.1% (+9.0 pts)2021: 13.6% (+4.5 pts)2022: 11.9% (−1.8 pts)2023: 10.3% (−1.6 pts)2024: 14.6% (+4.3 pts)2025: 21.2% (+6.6 pts)
20162025

IRWD valuation history

Fiscal year-endToday10-year median

IRWD returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

IRWD debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

IRWD cash returned to shareholders

DividendsBuybacksFree cash flow

IRWD price vs earnings per share

Share price at year-endEPS (right axis)

IRWD key metrics

2016–2025
Ironwood Pharmaceuticals, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$599.1M$709.2M$1.78B$2.31B$1.92B$1.83B$2.08B$1.32B$1.87B$1.87B
Enterprise value$981.4M$1.22B$2.40B$2.07B$1.77B$1.92B$2.33B$1.56B$2.05B$1.93B
P/E ratio24.9805.9—13.23.617.296.6———
Price / sales2.02.04.05.64.64.74.83.86.36.8
Price / book———3.53.229.2——189.828.0
Price / free cash flow4.76.99.78.47.311.0587.3———
Price / operating cash flow4.76.89.78.47.310.8193.6———
EV / sales3.33.55.45.04.34.95.44.56.97.1
EV / EBITDA9.412.512.27.97.613.518.1———
EV / free cash flow7.711.813.17.66.811.5659.2———
Earnings yield4.0%0.1%−56.4%7.6%27.6%5.8%1.0%−21.3%−6.3%−4.4%
Free cash flow yield21.2%14.6%10.3%11.9%13.6%9.1%0.2%−6.0%−5.6%−6.9%
Dividend yield———4.8%————0.0%0.0%
Shareholder yield (dividends + buybacks)—0.0%0.0%10.3%1.3%0.0%0.0%0.0%0.0%0.0%
Share price at fiscal year-end$3.37$4.43$11.44$12.39$11.66$11.39$13.31$8.67$12.55$12.80
Per share
Revenue per share$1.67$2.20$2.85$2.20$2.52$2.42$2.75$2.27$2.00$1.88
Earnings per share$0.14$0.01−$6.45$0.94$3.21$0.66$0.14−$1.85−$0.78−$0.56
Operating cash flow per share$0.71$0.65$1.18$1.47$1.59$1.05$0.07−$0.46−$0.67−$0.17
Free cash flow per share$0.71$0.65$1.18$1.47$1.59$1.04$0.02−$0.52−$0.70−$0.89
Cash per share$1.21$0.55$0.59$3.52$3.77$2.27$1.13$1.13$1.49$2.09
Book value per share−$1.47−$1.88−$2.23$3.50$3.69$0.39−$0.60−$1.29$0.07$0.46
Tangible book value per share−$1.48−$1.90−$2.25$3.50$3.69$0.39−$0.60−$1.29−$1.01−$0.69
Dividends per share———$0.60————$0.00$0.00
Capex per share$0.00$0.00$0.00$0.00$0.00$0.01$0.05$0.06$0.03$0.71
Debt per share$3.36$3.74$4.60$2.23$2.89$2.82$2.76$2.71$2.69$2.56
Shares outstanding177.8M160.1M155.4M186.3M164.4M160.7M156.0M152.6M149.0M145.9M
Change in shares outstanding+11.0%+3.0%−16.6%+13.3%+2.3%+3.0%+2.2%+2.4%+2.1%+2.6%
Returns & profitability
Return on equity (ROE)———27.8%158.1%———−305.5%−101.0%
Return on invested capital (ROIC)36.0%19.1%−216.7%39.7%75.7%89.1%58.5%−162.0%−37.9%−47.8%
Return on assets (ROA)6.4%0.2%−127.5%15.7%62.7%22.1%5.9%−60.2%−17.8%−12.3%
Return on tangible assets6.1%0.3%−214.4%15.9%46.9%19.0%5.3%−85.2%−26.3%−15.0%
Free cash flow margin42.9%29.4%41.4%66.6%63.2%42.9%0.8%−22.9%−34.8%−47.3%
Income quality (OCF / net income)5.29117.67—1.560.501.590.50———
Financial health
Total debt$597.8M$599.5M$715.5M$415.9M$475.8M$453.7M$431.2M$413.9M$400.2M$372.9M
Cash & short-term investments$215.5M$88.6M$92.2M$656.2M$620.1M$364.3M$177.0M$173.2M$221.4M$305.2M
Net debt$382.3M$510.9M$623.4M−$240.3M−$144.3M$89.4M$254.2M$240.8M$178.8M$67.7M
Debt / equity———0.640.797.24——40.635.59
Debt / assets1.511.711.520.380.420.811.071.250.660.53
Net debt / EBITDA3.655.233.16−0.92−0.620.631.98———
Current ratio1.134.690.8430.584.6115.417.502.234.724.17
Quick ratio1.134.690.8430.534.6015.417.482.234.714.16
Interest coverage3.62.8-43.732.97.54.83.3-6.3-2.1-1.3
Working capital$32.0M$143.5M−$42.8M$755.1M$583.5M$463.7M$265.9M$146.9M$245.6M$289.1M
Invested capital$120.5M$209.6M$277.1M$412.1M$461.6M$152.0M$160.9M$44.4M$188.6M$134.4M
Tangible asset value−$263.9M−$304.2M−$350.0M$652.4M$605.9M$61.9M−$94.0M−$197.2M−$150.8M−$100.2M
Net current asset value−$384.6M−$469.9M−$584.1M$332.5M$224.2M−$759,000−$189.1M−$262.0M−$284.2M−$262.9M
Graham number———$8.60$16.32$2.41————
Graham net-net per share−$2.30−$3.14−$4.04$1.58$1.13−$0.25−$1.48−$1.93−$2.10−$1.98
Capital allocation
Dividends paid———$111.2M————$0$0
Share buybacks (net)—$0$0$126.4M$24.1M$0$0$0$0$0
Dividend payout ratio———63.5%——————
Dividends + buybacks / free cash flow—0.0%0.0%86.8%9.2%0.0%0.0%———
Capex / revenue0.0%0.0%0.1%0.0%0.1%0.5%1.7%2.5%1.4%38.0%
Capex / operating cash flow0.0%0.1%0.1%0.0%0.1%1.1%67.0%———
Capex / depreciation0.020.070.170.100.180.521.290.720.299.25
Stock-based compensation / revenue5.8%8.5%7.2%6.6%5.4%8.0%7.3%12.7%11.3%10.7%
R&D / revenue32.1%31.7%26.2%10.8%17.0%22.6%28.5%48.0%49.7%50.9%
SG&A / revenue27.8%41.1%33.4%28.3%26.9%35.9%40.3%69.6%78.2%63.3%
Efficiency
Days sales outstanding79.3109.6100.8102.0104.3112.384.485.989.979.5
Days of inventory on hand——37.1321.83.237.70.9—17.1105.6
Days payables outstanding487.5240.6246.8182.54.1357.827.5171.9316.62,568.7
Cash conversion cycle (days)-408.3-131.0-108.8241.3103.4-207.857.8-81.9-209.5-2,383.5
Receivables turnover4.603.333.623.583.503.254.324.254.064.59
Payables turnover0.751.521.482.0088.231.0213.292.121.150.14
Inventory turnover——9.841.13112.659.68417.87—21.373.46
Asset turnover0.790.860.560.370.490.811.170.740.450.41
Average receivables$64.3M$105.5M$122.3M$114.8M$118.2M$119.8M$99.1M$81.6M$73.5M$59.7M
Average payables$2.5M$5.0M$4.2M$709,000$798,000$3.1M$10.2M$15.4M$16.8M$13.1M
Average inventory——$625,000$1.2M$625,000$324,000$324,000$367,500$908,000$540,500
Intangibles / total assets0.5%0.8%0.8%0.0%0.0%0.1%0.2%0.2%26.5%23.5%

Computed from IRWD's annual financial statements (latest annual report filed February 26, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

IRWD valuation and financial ratios

At the end of fiscal 2025 (December 31, 2025), Ironwood Pharmaceuticals traded at 24.9 times earnings, against a 10-year median of 21.1. Based on the latest twelve months, the trailing P/E is 4.5 and the forward P/E is 12.3. Ironwood Pharmaceuticals earned a return on invested capital of 36.0% in fiscal 2025. It ended the year with $597.8 million of debt and $215.5 million in cash and short-term investments, net debt of $382.3 million. The share count rose 21.8% from 145.9M to 177.8M over 9 years.

See the IRWD income statement, the IRWD chart for price history, or the IRWD stock overview for the latest quote and news.

IRWD key metrics FAQ

What is Ironwood Pharmaceuticals's P/E ratio?

Ironwood Pharmaceuticals's trailing P/E ratio is 4.5 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 12.3. At the end of fiscal 2025 it was 24.9, compared with a 10-year median of 21.1.

What is Ironwood Pharmaceuticals's EV/EBITDA?

Ironwood Pharmaceuticals's enterprise value was 9.4 times EBITDA at the end of fiscal 2025 (enterprise value $981.4 million, EBITDA $104.7 million); the current EV/EBITDA is 4.2.

What is Ironwood Pharmaceuticals's ROIC?

Ironwood Pharmaceuticals's return on invested capital was 36.0% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Ironwood Pharmaceuticals have?

Ironwood Pharmaceuticals had total debt of $597.8 million at the end of fiscal 2025 and $382.3 million of net debt (3.65 times EBITDA).

What is Ironwood Pharmaceuticals's free cash flow yield?

Ironwood Pharmaceuticals generated $127.0 million of free cash flow in fiscal 2025, a free cash flow yield of 21.2% on its market value at year-end ($599.1 million).

What is Ironwood Pharmaceuticals's current ratio?

Ironwood Pharmaceuticals's current ratio was 1.13 at the end of fiscal 2025: current assets were 1.13 times current liabilities.

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