Cryoport, Inc. (CYRX) Key Metrics

NASDAQ: CYRXValuation, returns, debt and efficiency ratios over 10 years.

CYRX valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$852.9M
Enterprise value
$768.0M
P/E (TTM)
—
Forward P/E
79.4
PEG ratio
62.13
Price / sales
4.6
10-yr median 9.1
Price / book
2.0
10-yr median 4.3
EV / EBITDA
—
Dividend yield
—
Beta
1.96

CYRX key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

CYRX valuation Price multiples at each fiscal year-end price.

Price / sales+67.8%
2.7
2025 · hover or tap a bar for each year
2016: 6.02017: 16.5 (+175.0%)2018: 15.9 (−3.9%)2019: 16.2 (+2.1%)2020: 21.5 (+32.8%)2021: 12.2 (−43.3%)2022: 3.6 (−70.7%)2023: 3.2 (−10.7%)2024: 1.6 (−49.2%)2025: 2.7 (+67.8%)
20162025
Price / book+1.4%
1.0
2025 · hover or tap a bar for each year
2016: 8.12017: 11.0 (+36.0%)2018: 8.1 (−26.8%)2019: 4.4 (−46.1%)2020: 4.4 (+1.6%)2021: 4.2 (−4.3%)2022: 1.4 (−66.1%)2023: 1.6 (+8.2%)2024: 0.9 (−39.2%)2025: 1.0 (+1.4%)
20162025
Free cash flow yield+3.0 pts
−5.8%
2025 · hover or tap a bar for each year
2016: −14.7%2017: −2.7% (+12.0 pts)2018: −2.0% (+0.7 pts)2019: −1.2% (+0.8 pts)2020: −1.4% (−0.2 pts)2021: −0.6% (+0.8 pts)2022: −3.3% (−2.6 pts)2023: −6.0% (−2.7 pts)2024: −8.9% (−2.8 pts)2025: −5.8% (+3.0 pts)
20162025

CYRX valuation history

Fiscal year-endToday10-year median

CYRX returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

CYRX debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

CYRX cash returned to shareholders

DividendsBuybacksFree cash flow

CYRX price vs earnings per share

Share price at year-endEPS (right axis)

CYRX key metrics

2016–2025
Cryoport, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$480.7M$379.2M$758.8M$796.8M$2.72B$1.69B$549.7M$311.2M$197.3M$46.1M
Enterprise value$300.2M$368.1M$718.1M$709.4M$2.52B$1.73B$460.2M$278.7M$182.2M$42.2M
P/E ratio6.1—————————
Price / sales2.71.63.23.612.221.516.215.916.56.0
Price / book1.00.91.61.44.24.44.48.111.08.1
Price / operating cash flow————334.4—————
EV / sales1.71.63.03.211.322.013.614.215.25.5
Earnings yield16.3%−26.3%−4.9%−34.6%−10.1%−1.9%−3.3%−3.1%−4.0%−28.5%
Free cash flow yield−5.8%−8.9%−6.0%−3.3%−0.6%−1.4%−1.2%−2.0%−2.7%−14.7%
Dividend yield1.7%2.1%1.1%1.0%0.3%0.2%———2,318.0%
Shareholder yield (dividends + buybacks)3.7%2.1%1.1%5.8%0.3%0.2%0.0%0.0%0.0%12,986.5%
Share price at fiscal year-end$9.60$7.78$15.49$17.35$59.17$43.88$16.46$11.03$8.59$3.24
Per share
Revenue per share$3.52$4.79$4.84$4.85$4.85$2.04$1.02$0.70$0.52$0.54
Earnings per share$1.56−$2.04−$0.76−$6.00−$6.00−$0.85−$0.55−$0.34−$0.34−$0.92
Operating cash flow per share−$0.17−$0.33−$0.02−$0.04$0.18−$0.39−$0.04−$0.12−$0.16−$0.40
Free cash flow per share−$0.56−$0.69−$0.93−$0.57−$0.37−$0.64−$0.20−$0.22−$0.23−$0.48
Cash per share$8.21$5.37$9.32$11.39$13.69$2.42$2.82$1.68$0.66$0.32
Book value per share$10.04$8.25$9.98$12.10$13.97$9.92$3.78$1.37$0.78$0.40
Tangible book value per share$6.83$3.69$3.80$4.65$6.39$0.61$3.30$1.36$0.77$0.40
Dividends per share$0.16$0.16$0.16$0.17$0.18$0.07———$75.10
Capex per share$0.39$0.35$0.92$0.53$0.54$0.25$0.16$0.10$0.08$0.08
Debt per share$4.61$5.14$8.49$9.49$9.30$3.39$0.14$0.52$0.00$0.05
Shares outstanding50.1M48.7M49.0M45.9M45.9M38.6M33.4M28.2M23.0M14.2M
Change in shares outstanding+2.7%−0.5%+6.7%0.0%+19.0%+15.5%+18.4%+22.9%+61.5%—
Returns & profitability
Return on equity (ROE)17.3%−22.4%−7.1%−46.0%−53.8%−12.8%−22.2%−33.9%−67.0%−245.8%
Return on invested capital (ROIC)−8.2%−21.7%−5.5%−3.1%−3.3%−10.4%−65.2%−153.4%−268.0%−546.9%
Return on assets (ROA)10.7%−12.0%−3.7%−25.6%−33.1%−9.5%−19.0%−24.9%−55.7%−168.4%
Return on tangible assets13.0%−20.7%−5.7%−39.6%−36.0%−16.9%−15.3%−16.9%−39.2%−161.8%
Free cash flow margin−15.9%−14.4%−19.2%−11.7%−7.6%−31.2%−19.8%−32.2%−45.0%−88.4%
Income quality (OCF / net income)−0.11—————————
Financial health
Total debt$230.7M$250.7M$416.0M$435.9M$427.1M$130.9M$4.8M$14.8M$0$651,934
Cash & short-term investments$411.2M$261.7M$456.8M$523.3M$628.8M$93.3M$94.3M$47.3M$15.0M$4.5M
Net debt−$180.5M−$11.0M−$40.8M−$87.4M−$201.7M$37.6M−$89.5M−$32.5M−$15.0M−$3.9M
Debt / equity0.460.620.850.780.670.340.040.380.000.11
Debt / assets0.300.360.430.420.380.240.040.260.000.08
Current ratio2.175.2911.7314.7916.264.2018.8516.917.922.73
Quick ratio2.074.9411.1614.1115.883.9018.7716.847.862.69
Interest coverage-15.6-20.9-5.2-3.8-3.8-11.7-12.9-124.8-502.9-62.9
Working capital$257.2M$277.0M$489.5M$563.3M$650.9M$112.1M$97.5M$48.7M$15.1M$3.9M
Invested capital$322.1M$390.9M$448.3M$468.4M$440.1M$420.3M$36.8M$6.1M$2.8M$1.8M
Tangible asset value$342.2M$179.8M$186.2M$213.7M$293.4M$23.5M$110.1M$38.4M$17.8M$5.7M
Net current asset value$213.8M$40.0M$66.4M$121.3M$222.4M−$22.6M$93.4M$33.7M$14.9M$3.7M
Graham number$18.79—————————
Graham net-net per share$3.70$0.12$0.67$1.90$4.26−$1.23$2.70$1.13$0.61$0.21
Capital allocation
Dividends paid$8.0M$8.0M$8.0M$8.0M$8.2M$2.8M———$1.07B
Share buybacks (net)$10.0M$0$0$38.0M$0$0$0$0$0$4.92B
Dividend payout ratio10.2%—————————
Capex / revenue11.1%7.4%18.9%10.9%11.2%12.3%15.9%15.1%15.1%13.9%
Capex / operating cash flow————307.7%—————
Capex / depreciation0.700.561.631.061.240.982.243.452.712.85
Stock-based compensation / revenue6.3%8.4%9.6%9.0%6.9%11.3%48.7%27.9%29.7%40.6%
R&D / revenue9.7%7.7%6.6%7.6%7.6%12.1%11.0%9.4%10.1%7.8%
SG&A / revenue58.4%63.9%59.3%53.9%43.8%72.3%92.2%86.8%105.8%146.8%
Efficiency
Days sales outstanding82.068.766.168.358.089.257.248.143.143.1
Days of inventory on hand89.566.373.764.039.147.47.66.56.25.7
Days payables outstanding81.271.272.680.677.4117.846.356.672.076.5
Cash conversion cycle (days)90.263.967.251.719.818.918.6-2.0-22.7-27.8
Receivables turnover4.455.315.525.356.294.096.387.598.488.47
Payables turnover4.495.135.024.534.723.107.896.445.074.77
Inventory turnover4.085.504.955.719.327.7047.7755.9958.6264.30
Asset turnover0.240.280.240.210.270.230.350.510.840.99
Average receivables$39.6M$43.9M$43.0M$41.6M$35.4M$19.2M$5.3M$2.6M$1.4M$906,132
Average payables$20.7M$26.1M$26.6M$27.8M$26.7M$13.7M$2.1M$1.5M$1.2M$959,498
Average inventory$22.8M$24.3M$26.9M$22.1M$13.5M$5.5M$347,257$167,655$102,148$71,190
Intangibles / total assets21.0%31.6%31.6%32.9%31.3%65.0%11.9%0.2%0.4%0.1%

Computed from CYRX's annual financial statements (latest annual report filed March 5, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

CYRX valuation and financial ratios

At the end of fiscal 2025 (December 31, 2025), Cryoport traded at 6.1 times earnings. Cryoport earned a return on equity of 17.3% and a return on invested capital of −8.2% in fiscal 2025. It ended the year with $230.7 million of debt and $411.2 million in cash and short-term investments, a net cash position of $180.5 million. It returned $18.0 million to shareholders: $8.0 million in dividends and $10.0 million in share buybacks. The share count rose 252.1% from 14.2M to 50.1M over 9 years.

See the CYRX income statement, the CYRX chart for price history, or the CYRX stock overview for the latest quote and news.

CYRX key metrics FAQ

What is Cryoport's P/E ratio?

Cryoport traded at 6.1 times earnings at the end of fiscal 2025.

What is Cryoport's return on equity?

Cryoport's return on equity (ROE) was 17.3% in fiscal 2025: net income of $78.3 million on average shareholders' equity of $452.3 million.

What is Cryoport's ROIC?

Cryoport's return on invested capital was −8.2% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Cryoport have?

Cryoport had total debt of $230.7 million at the end of fiscal 2025, a debt-to-equity ratio of 0.46 and more cash than debt.

What is Cryoport's dividend yield?

Cryoport paid $8.0 million in dividends in fiscal 2025 ($0.16 per share), a payout ratio of 10.2%.

Does Cryoport buy back its shares?

Yes. Cryoport spent $10.0 million on net share repurchases in fiscal 2025 Shares outstanding changed +2.7% over the year, to 50.1M..

What is Cryoport's free cash flow yield?

Cryoport generated -$28.1 million of free cash flow in fiscal 2025, a free cash flow yield of −5.8% on its market value at year-end ($480.7 million).

What is Cryoport's current ratio?

Cryoport's current ratio was 2.17 at the end of fiscal 2025: current assets were 2.17 times current liabilities.

Integrated Freight & Logistics key metrics