Xencor, Inc. (XNCR) Income Statement

NASDAQ: XNCRRevenue, profits, margins and EPS over 10 years.

XNCR 2025 at a glance

Fiscal year ended December 31, 2025 · U.S. dollars
Revenue+13.7%
$125.6M
2025 · hover or tap a bar for each year
2016: $87.5M (+215.3%)2017: $35.7M (−59.2%)2018: $40.6M (+13.7%)2019: $156.7M (+285.9%)2020: $122.7M (−21.7%)2021: $275.1M (+124.2%)2022: $164.6M (−40.2%)2023: $168.3M (+2.3%)2024: $110.5M (−34.4%)2025: $125.6M (+13.7%)
20162025
Gross profit
$115.1M
2025 · hover or tap a bar for each year
2016: $87.5M (+215.3%)2017: $35.7M (−59.2%)2018: $40.6M (+13.7%)2019: $38.1M (−6.1%)2020: $122.7M (+221.9%)2021: $275.1M (+124.2%)2022: $164.6M (−40.2%)2023: −$85.3M (−151.8%)2024: −$117.2M2025: $115.1M
20162025
Operating income
−$177.5M
2025 · hover or tap a bar for each year
2016: $22.5M2017: −$53.6M (−337.6%)2018: −$79.4M2019: $13.8M2020: −$76.8M (−655.5%)2021: $43.8M2022: −$82.5M (−288.4%)2023: −$138.6M2024: −$178.4M2025: −$177.5M
20162025
Net income
−$91.9M
2025 · hover or tap a bar for each year
2016: $23.6M2017: −$48.9M (−307.1%)2018: −$70.4M2019: $26.9M2020: −$63.5M (−336.4%)2021: $82.6M2022: −$55.2M (−166.8%)2023: −$126.1M2024: −$232.6M2025: −$91.9M
20162025
EPS (diluted)
−$1.24
2025 · hover or tap a bar for each year
2016: $0.562017: −$1.04 (−285.7%)2018: −$1.352019: $0.452020: −$1.21 (−368.9%)2021: $1.352022: −$0.93 (−168.9%)2023: −$2.102024: −$3.512025: −$1.24
20162025
Net profit margin+137.3 pts
−73.2%
2025 · hover or tap a point for each year
2016: 27.0% (+90.4 pts)2017: −137.0% (−164.0 pts)2018: −173.4% (−36.4 pts)2019: 17.2% (+190.6 pts)2020: −51.8% (−68.9 pts)2021: 30.0% (+81.8 pts)2022: −33.5% (−63.6 pts)2023: −74.9% (−41.4 pts)2024: −210.5% (−135.6 pts)2025: −73.2% (+137.3 pts)
20162025

XNCR revenue and net income

RevenueNet incomeNet margin (right axis)

Where XNCR's revenue goes

2025
Revenue
$125.6M100.0%
Cost of revenue
−$10.5M−8.4%
Gross profit
$115.1M91.6%
Research & development
−$239.4M−190.7%
Sales, general & admin
−$63.6M−50.7%
Other operating expenses
$10.5M8.4%
Operating income
−$177.5M−141.4%
Interest & other income
$88.1M70.1%
Income taxes
−$2.5M−2.0%
Net income
−$91.9M−73.2%

Each bar shows an amount and its share of revenue. XNCR kept −73.2% of revenue as net income.

XNCR profit margins

GrossOperatingNet

XNCR growth rates

to 2025
1 year3 years5 years10 years
Revenue+13.7%−8.6%+0.5%+16.3%
Gross profit—−11.2%−1.3%+15.3%
Operating income————
Net income————
EPS (diluted)————

1-year change and average annual growth (CAGR) over 3, 5 and 10 fiscal years. "—" when a starting value was zero or negative.

XNCR quarterly EPS vs estimates

Reported EPSAnalyst estimate

Xencor beat the analyst EPS estimate in 6 of the last 8 quarters. Next report: November 4, 2026 (estimate $-0.35).

XNCR income statement

Xencor, Inc. annual income statement
2025202420232022202120202019201820172016
Revenue$125.6M$110.5M$168.3M$164.6M$275.1M$122.7M$156.7M$40.6M$35.7M$87.5M
Cost of revenue$10.5M$227.7M$253.6M$8.8M$7.5M$169.8M$118.6M$97.5M$71.8M$51.9M
Gross profit$115.1M−$117.2M−$85.3M$164.6M$275.1M$122.7M$38.1M$40.6M$35.7M$87.5M
Research & development$239.4M$227.7M$253.6M$199.6M$192.5M$169.8M$118.6M$97.5M$71.8M$51.9M
Sales, general & admin$63.6M$50.1M$53.4M$47.5M$43.2M$29.7M$24.3M$22.5M$17.5M$13.1M
Total operating expenses$292.6M$61.2M$307.0M$247.1M$231.3M$199.5M$24.3M$120.0M$89.3M$65.0M
Operating income−$177.5M−$178.4M−$138.6M−$82.5M$43.8M−$76.8M$13.8M−$79.4M−$53.6M$22.5M
Interest income$27.5M$31.9M$13.7M$4.8M$849,000$7.3M$13.6M$9.1M$4.2M$2.1M
Interest expense$31.9M$36.6M$6.2M$36.8M$7.5M$0$17.7M$16,000$13,000$21,000
Income before taxes−$89.4M−$234.9M−$120.4M−$54.5M$82.6M−$69.3M$27.2M−$70.4M−$49.4M$24.6M
Income taxes$2.5M$1.6M$5.8M$673,000−$7.5M−$5.8M$312,000$9.0M−$463,000$991,000
Net income−$91.9M−$232.6M−$126.1M−$55.2M$82.6M−$63.5M$26.9M−$70.4M−$48.9M$23.6M
EBITDA−$47.0M−$186.2M−$125.9M−$73.7M$51.3M−$71.0M$18.1M−$76.1M−$51.5M$24.0M
EPS (diluted)−$1.24−$3.51−$2.10−$0.93$1.35−$1.21$0.45−$1.35−$1.04$0.56
Gross margin91.6%−106.1%−50.6%100.0%100.0%100.0%24.3%100.0%100.0%100.0%
Operating margin−141.4%−161.5%−82.4%−50.1%15.9%−62.6%8.8%−195.5%−150.0%25.8%
Net margin−73.2%−210.5%−74.9%−33.5%30.0%−51.8%17.2%−173.4%−137.0%27.0%

Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported in XNCR's financial statements (latest annual report filed February 25, 2026); data from EODHD. Sales, general & administrative expenses include sales and marketing.

XNCR financial results

In fiscal year 2025 (ended December 31, 2025), Xencor reported revenue of $125.6 million, up 13.7% from the year before. It had a net loss of $91.9 million, a net profit margin of −73.2%. Diluted earnings per share came to −$1.24. Over five years revenue grew at an average rate of 0.5% a year.

See the XNCR stock overview for the latest quote and news, or the XNCR chart for price history and technical indicators.

XNCR income statement FAQ

What is Xencor's annual revenue?

Xencor reported total revenue of $125.6 million for fiscal year 2025, which ended on December 31, 2025. That was up 13.7% from $110.5 million the previous year.

Is Xencor profitable?

No. Xencor reported a net loss of $91.9 million in fiscal 2025, a net profit margin of −73.2%; its operating margin was −141.4%.

What is Xencor's gross margin?

Xencor's gross margin was 91.6% in fiscal 2025: for every $100 of revenue, Xencor kept $92 after the direct cost of its products and services.

How much does Xencor spend on research and development?

Xencor spent $239.4 million on research and development in fiscal 2025, 190.7% of revenue.

How fast is Xencor growing?

Revenue grew 0.5% a year on average over the last five fiscal years, from $122.7 million to $125.6 million.

What are Xencor's earnings per share?

Xencor earned $-1.24 per diluted share in fiscal 2025, compared with $-3.51 a year earlier.

When will Xencor report its next earnings?

Xencor is expected to report results for the quarter ending September 30, 2026 on November 4, 2026 after the market closes.

When does Xencor's fiscal year end?

Xencor's fiscal year ends in December. The latest annual report covers the year ended December 31, 2025 and was filed on February 25, 2026.

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