Ionis Pharmaceuticals, Inc. (IONS) Stock Forecast

NASDAQ: IONSAnalyst ratings, price target and estimates.

IONS analyst forecast

as of October 18, 2026
Analyst consensus
Buy
4.24 / 5 from 25 analysts
Price target
$83.83
average of analyst targets
Upside to target
+95.2%
from the latest close
Next earnings
November 4, 2026
EPS estimate $-1.20
52-week range
$42.38 – $86.50

IONS analyst ratings

25 analysts
Strong buy
1144%
Buy
936%
Hold
520%
Sell
00%
Strong sell
00%

Number of analysts at each rating.

IONS price target

Price $42.94Target $83.83
52-week low $42.3852-week high $86.50

The average of analyst 12-month price targets compared with the latest close and the 52-week range.

IONS earnings per share estimates

Ionis Pharmaceuticals, Inc. EPS estimates
PeriodAverageLowHighYear agoGrowthAnalysts
Current quarter (Sep '26)−$0.92−$1.06−$0.65−$0.61−49.6%8
Current fiscal year (2026)−$2.70−$3.70−$2.12−$1.54−75.0%10
Next fiscal year (2027)−$1.11−$2.47$0.60−$2.70+58.8%10

Consensus EPS estimates; growth compares the average estimate with the year-ago EPS.

IONS revenue estimates

Ionis Pharmaceuticals, Inc. revenue estimates
PeriodAverageLowHighGrowthAnalysts
Current quarter (Sep '26)$186.5M$160.0M$225.0M+18.8%19
Current fiscal year (2026)$919.1M$783.0M$1.18B−2.6%24
Next fiscal year (2027)$1.36B$1.07B$2.09B+48.2%24

IONS EPS: reported and forecast

Reported EPSEstimate (average; low–high)

Fiscal years; "E" marks estimates, the line shows the range from the lowest to the highest estimate.

IONS revenue: reported and forecast

Reported revenueEstimate (average; low–high)

IONS EPS estimate revisions

Ionis Pharmaceuticals, Inc. EPS estimate revisions
Period90 days ago60 days ago30 days ago7 days agoNowChange (90 d)Revisions (30 d)
Current quarter (Sep '26)−$0.84−$0.81−$0.92−$0.92−$0.92+8.7%1 up · 5 down
Current fiscal year (2026)−$2.69−$2.62−$2.59−$2.70−$2.70+0.6%3 up · 0 down
Next fiscal year (2027)−$0.61−$1.07−$1.05−$1.11−$1.11+82.8%3 up · 3 down

How the consensus EPS estimate changed over the last 90 days, and how many analysts raised or lowered it in the last 30 days.

IONS earnings surprises

Reported EPSEstimate

Reported EPS vs the consensus estimate for the last 12 quarters; IONS beat in 12 of 12.

What analysts expect from IONS

25 analysts cover Ionis Pharmaceuticals; their consensus rating is buy (4.24 on a 1–5 scale, where 5 is a strong buy). The average price target is $83.83, 95.2% above the latest close of $42.94. Analysts expect earnings of −$2.70 per share for 2026, −75.0% from a year earlier. For 2027 the average estimate is −$1.11 per share on revenue of $1.4 billion. Ionis Pharmaceuticals beat the EPS estimate in 12 of the last 12 quarters.

Related: IONS income statement, IONS key metrics, IONS chart. See the IONS stock overview for the latest quote and news.

IONS forecast FAQ

What is Ionis Pharmaceuticals's price target?

The average analyst price target for Ionis Pharmaceuticals is $83.83, 95.2% above the latest close of $42.94.

Is Ionis Pharmaceuticals a buy, hold or sell?

Of 25 analysts covering Ionis Pharmaceuticals, 11 rate it a strong buy, 9 a buy, 5 a hold, 0 a sell and 0 a strong sell, a consensus of buy. Ratings are opinions, not a recommendation from Quotelinks.

What is Ionis Pharmaceuticals's EPS forecast?

Analysts forecast −$2.70 per share for 2026 (range −$3.70 to −$2.12); for 2027 the estimate is −$1.11.

What is Ionis Pharmaceuticals's revenue forecast?

The average revenue estimate for 2026 is $919.1 million, growth of −2.6%; for 2027 it is $1.4 billion.

When does Ionis Pharmaceuticals report earnings?

Ionis Pharmaceuticals is expected to report results for the quarter ending September 30, 2026 on November 4, 2026 before the market opens; the EPS estimate is $-1.20.

Does Ionis Pharmaceuticals usually beat earnings estimates?

Ionis Pharmaceuticals reported EPS at or above the analyst estimate in 12 of the last 12 quarters.

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