Rigel Pharmaceuticals, Inc. (RIGL) AI Stock Analysis
RIGL AI stock analysis summary
AI ResearchRigel Pharmaceuticals, Inc. (RIGL) is a commercial-stage biotechnology company focused on hematologic disorders, cancer, and rare immune diseases. The company expanded annual revenue by 64.1% in FY2025 to $294.3M, yielding net income of $367.0M. Over the trailing twelve months ended June 30, 2026, revenue stood at $276.8M, though latest quarterly revenue contracted 22.6% year-over-year.
- Market cap
- $858.7M
- Revenue (TTM)
- $276.8M
- P/E
- 2.7x fwd 9.3x
- 1Y return
- 63.5% S&P 500 16.8%
- Avg. target
- $63.00 37.0% vs last close
Bull case
- Annual revenue expanded 64.1% in FY2025 to $294.3M while producing $75.7M in free cash flow.
- Rigel trades at a forward P/E of 9.3x and EV/EBITDA of 9.1x, both below the US-listed Healthcare peer medians of 17.3x and 12.0x.
- Wall Street analysts set a mean price target of $63.00, implying 37.0% upside compared to the October 16, 2026 closing price of $45.97.
Bear case
- In the latest quarter ended June 30, 2026, quarterly revenue fell 22.6% year-over-year and quarterly earnings declined 73.2%.
- Analyst estimates forecast EPS to drop 44.9% to $3.54 for the fiscal year ending December 31, 2026.
- The stock has a short interest representing 15.7% of its float and an earnings track record of beating EPS estimates in only 1 of the last 4 quarters.
What Rigel Pharmaceuticals does
Rigel Pharmaceuticals, Inc. is a South San Francisco-based biotechnology company founded in 1996 that discovers and develops small molecule drugs for hematologic disorders, cancer, and rare immune diseases. Its commercialized offerings include Tavalisse, an oral spleen tyrosine kinase inhibitor for adult chronic immune thrombocytopenia, and Rezlidhia, a non-intensive monotherapy for adult relapsed or refractory acute myeloid leukemia with an IDH1 mutation. In clinical development, the company has evaluated Fostamatinib in Phase III trials for warm autoimmune hemolytic anemia and COVID-19. Rigel also maintains clinical partnerships with Eli Lilly and Company, BerGenBio ASA, and Daiichi Sankyo.
Growth and profitability
Rigel delivered a 5-year revenue CAGR of 22.1% from FY2020 to FY2025. Following annual revenue declines of 19.4% in FY2022 to $120.2M and 2.8% in FY2023 to $116.9M, top-line growth rebounded 53.4% in FY2024 to $179.3M. In FY2025, revenue rose 64.1% to $294.3M, supported by a 93.3% gross margin and an operating margin of 42.6%. Net income reached $367.0M in FY2025, compared to $17.5M in FY2024 and net losses of -$25.1M in FY2023 and -$58.6M in FY2022. For the latest quarter ended June 30, 2026, revenue fell 22.6% year-over-year, and earnings decreased 73.2%.
Balance sheet and cash flow
As of June 30, 2026, Rigel held $95.3M in cash and short-term investments against total debt of $40.0M, resulting in net cash of $55.4M. The company maintains a current ratio of 1.95, total assets of $521.1M, and shareholders' equity of $425.4M, with a debt-to-equity ratio of 0.09. Cash generation improved significantly in recent periods, producing $75.7M in operating cash flow and $75.7M in free cash flow during FY2025. Over 5 years, the company's share count increased 14.4%.
Valuation and performance
Rigel trades at a trailing price-to-earnings multiple of 2.7x, compared to 24.6x for the median of its US-listed Healthcare peers. Its forward price-to-earnings ratio is 9.3x versus the peer median of 17.3x, while enterprise value to EBITDA sits at 9.1x against the peer median of 12.0x. The company has a market cap of $858.7M and an enterprise value of $856.6M. Over the past year, Rigel's stock gained 63.5%, outperforming the S&P 500 (SPY) return of 16.8%, though its 5-year return of 36.0% lagged the S&P 500 return of 83.0%.
What analysts expect
Consensus ratings include 3 Strong Buy and 2 Hold recommendations from Wall Street analysts. The mean price target is $63.00, representing a 37.0% premium over the last close of $45.97. For the fiscal year ending December 31, 2026, analysts project revenue of $305.7M and EPS of $3.54, which indicates a 44.9% decline in earnings per share. For the following fiscal year, 4 analysts estimate revenue to grow 21.9% to $372.8M and EPS to increase 39.4% to $4.94. Rigel beat EPS estimates in 1 of the last 4 quarters, and its next earnings date is November 3, 2026.
Key risks and what to watch
- Revenue and earnings can fluctuate widely, as seen when annual revenue declined 19.4% in FY2022 to $120.2M.
- Short interest stands at 15.7% of the float, reflecting meaningful bearish positioning among market participants.
- The company's five-year share count grew 14.4%, reflecting ongoing equity dilution over time.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this RIGL AI stock analysis
This page is an AI-written research summary of Rigel Pharmaceuticals, Inc. (RIGL). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: RIGL income statement, RIGL balance sheet, RIGL key metrics, RIGL analyst forecast, RIGL chart. See the RIGL stock overview for the latest quote and news.
RIGL AI stock analysis FAQ
What commercial treatments does Rigel Pharmaceuticals sell?
Rigel's commercialized portfolio includes Tavalisse for adult patients with chronic immune thrombocytopenia and Rezlidhia for adult relapsed or refractory acute myeloid leukemia with an IDH1 mutation.
What is Rigel's debt and cash situation?
As of June 30, 2026, Rigel held $95.3M in cash and short-term investments against $40.0M in total debt, giving it a net cash position of $55.4M and a debt-to-equity ratio of 0.09.
How did Rigel perform financially in FY2025?
In FY2025, Rigel generated $294.3M in revenue, up 64.1% year-over-year, and earned net income of $367.0M with $75.7M in operating cash flow.
What are analysts forecasting for Rigel's future earnings?
Analysts estimate EPS of $3.54 on revenue of $305.7M for FY2026, followed by EPS of $4.94 on revenue of $372.8M for the next fiscal year.