Nanobiotix S.A. (NBTX) AI Stock Analysis
NBTX AI stock analysis summary
AI ResearchNanobiotix S.A. (NBTX) is a clinical-stage biotechnology company developing nanoparticle-based cancer therapies. The company generated $11.5M in trailing twelve-month revenue but continues to operate at a loss with an operating margin of -322.9%. While its 1-year return stands at -19.8%, analysts maintain a mean price target of $54.03, representing a 153.7% upside to its last close of $21.30.
- Market cap
- $1.08B
- Revenue (TTM)
- $11.5M
- P/E
- — fwd 42.4x
- 1Y return
- -19.8% S&P 500 16.8%
- Avg. target
- $54.03 153.7% vs last close
Bull case
- Nanobiotix achieved a 5-year revenue CAGR of 66.4% from FY2020 through FY2025.
- Analysts maintain a mean price target of $54.03, suggesting 153.7% upside relative to the $21.30 share price.
- Forecasts for the next fiscal year point to 50.7% revenue growth, reaching $44.4M.
Bear case
- The company's quarterly revenue fell 79.2% year-over-year in the period ended June 30, 2026.
- Nanobiotix carries negative shareholders' equity of -$33.4M as of June 30, 2026.
- Cash burn remains persistent, with free cash flow of -$34.0M recorded in FY2025.
What Nanobiotix does
Nanobiotix S.A., headquartered in Paris, France, is an innovative clinical-stage biotechnology company established in 2003 that specializes in developing cancer therapies. Its lead product candidate is NBTXR3, a sterile aqueous suspension of crystalline hafnium oxide nanoparticles engineered to improve oncological treatment outcomes. NBTXR3 is designed for several cancer types, including soft tissue sarcoma, head and neck, liver, prostate, pancreatic, esophageal, rectal, and non-small cell lung cancers. The company has also entered into a strategic collaboration with LianBio to develop and commercialize NBTXR3 in Greater China, South Korea, Singapore, and Thailand.
Growth and profitability
Over a five-year period from FY2020 to FY2025, Nanobiotix posted a revenue CAGR of 66.4%. Revenue fluctuated significantly, moving from $2.6M in FY2021 to $36.2M in FY2023, before turning to -$7.2M in FY2024 and recovering to $29.6M in FY2025. Across all reported fiscal years, the gross margin remained at 100.0%. However, the company has consistently generated net losses, recording -$24.0M in FY2025 and -$68.1M in FY2024. For the latest quarter ending June 30, 2026, quarterly revenue growth declined 79.2% year-over-year, leading to a trailing twelve-month revenue of $11.5M and an operating margin of -322.9%.
Balance sheet and cash flow
As of June 30, 2026, Nanobiotix held $110.8M in cash and short-term investments alongside total debt of $106.6M, resulting in net cash of $4.3M. Total assets stood at $128.3M, and the current ratio was 1.44. The company reported negative shareholders' equity of -$33.4M. Cash burn has been sustained, with FY2025 operating cash flow of -$33.4M and free cash flow of -$34.0M. Capital expenditures in FY2025 totaled $546,000, while the five-year share count increased by 40.4%.
Valuation and performance
Nanobiotix trades at a forward P/E of 42.4x and a price-to-sales ratio of 94.3x, compared to the median of its US-listed Healthcare peers of 17.3x forward P/E and 4.1x price-to-sales. Its enterprise value to revenue multiple is 53.4x. The stock closed at $21.30 on October 16, 2026, sitting 36.3% below its 200-day moving average. Over the past year, the stock dropped 19.8%, trailing the S&P 500 (SPY) gain of 16.8%, though its 5-year return of 66.1% compares against the S&P 500's 83.0%.
What analysts expect
Wall Street analysts currently assign Nanobiotix 4 Strong Buy ratings and 1 Hold rating, with no Sell or Buy ratings. The mean price target is $54.03, reflecting a 153.7% premium over the last close of $21.30. For the current fiscal year ending December 31, 2026, consensus estimates project an EPS of -$0.54 on revenue of $29.4M. For the next fiscal year, analysts forecast revenue to expand 50.7% to $44.4M with an EPS of -$0.15. The company beat EPS estimates in 2 of the last 4 quarters.
Key risks and what to watch
- Operating margins on a trailing twelve-month basis are deeply negative at -322.9%.
- Dilution has been significant, evidenced by a 40.4% increase in the share count over five years.
- The balance sheet is levered with $106.6M in total debt against $110.8M in cash and short-term investments.
- Revenue has proven volatile, swinging from $36.2M in FY2023 to -$7.2M in FY2024.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this NBTX AI stock analysis
This page is an AI-written research summary of Nanobiotix S.A. (NBTX). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: NBTX income statement, NBTX balance sheet, NBTX key metrics, NBTX analyst forecast, NBTX chart. See the NBTX stock overview for the latest quote and news.
NBTX AI stock analysis FAQ
What is Nanobiotix's core product?
Nanobiotix is developing NBTXR3, a crystalline hafnium oxide nanoparticle suspension designed to treat multiple cancer types, including head and neck, liver, and lung cancers.
Does Nanobiotix pay a dividend?
No, Nanobiotix does not pay a dividend.
What is Nanobiotix's net cash position?
As of June 30, 2026, the company held $110.8M in cash and short-term investments against $106.6M in total debt, giving it a net cash balance of $4.3M.
What are analysts' price targets for NBTX?
Analysts have established a mean price target of $54.03, which is 153.7% above the last closing price of $21.30.