Kymera Therapeutics, Inc. (KYMR) AI Stock Analysis
KYMR AI stock analysis summary
AI ResearchKymera Therapeutics, Inc. (KYMR) is a clinical-stage biopharmaceutical company focused on targeted protein degradation for immunology and oncology indications. In the latest quarter ended June 30, 2026, quarterly revenue grew 466.4% year-over-year, while trailing twelve months net margin stood at -285.3%. The company holds $608.8M in net cash as of June 30, 2026, supporting ongoing research and clinical development programs.
- Market cap
- $8.62B
- Revenue (TTM)
- $105.0M
- P/E
- —
- 1Y return
- 73.3% S&P 500 16.8%
- Avg. target
- $139.35 33.0% vs last close
Bull case
- Kymera generated quarterly revenue growth of 466.4% year-over-year in the latest quarter ended June 30, 2026.
- The company maintains a strong liquidity cushion with $608.8M in net cash and a current ratio of 9.83 as of June 30, 2026.
- Wall Street analysts set a mean price target of $139.35, implying a 33.0% upside over the last close of $104.78.
Bear case
- Kymera's annual net loss widened to -$311.4M in FY2025, accompanied by an operating margin of -891.3%.
- Free cash flow for FY2025 was -$234.3M, following operating cash flow of -$232.9M.
- Valuation is elevated with a price-to-sales ratio of 82.1x compared to the median of 4.1x for its US-listed Healthcare peers.
What Kymera Therapeutics does
Kymera Therapeutics, Inc. is a biopharmaceutical company specializing in the discovery and development of small molecule therapeutics that selectively degrade disease-causing proteins by leveraging the body's natural protein degradation system. Headquartered in Watertown, Massachusetts, the company advances multiple pipeline programs. Its IRAK4 program is in Phase I clinical trials for immunology-inflammation diseases like hidradenitis suppurativa, atopic dermatitis, rheumatoid arthritis, macrophage activation syndrome, and general pustular psoriasis. Additional pipeline assets include IRAKIMiD for MYD88-mutated diffuse large B cell lymphoma, STAT3 for hematologic malignancies, solid tumors, autoimmune diseases, and fibrosis, and MDM2 for hematological malignancies and solid tumors.
Growth and profitability
Kymera's financial results reflect high research spending and fluctuating collaboration revenues. Annual revenue decreased from $72.8M in FY2021 to $46.8M in FY2022, rose to $78.6M in FY2023, and fell to $47.1M in FY2024 and $39.2M in FY2025. Across the 5 years from FY2020 to FY2025, revenue achieved a 2.9% CAGR. Net income widened from -$100.2M in FY2021 to -$311.4M in FY2025 as R&D expense expanded to $316.6M. Operating margin in FY2025 was -891.3%, and EPS was -$3.68. For the latest quarter ended June 30, 2026, revenue increased 466.4% year-over-year, bringing trailing twelve months revenue to $105.0M with an EPS of -$3.25.
Balance sheet and cash flow
As of June 30, 2026, Kymera reported $691.0M in cash and short-term investments against $82.2M in total debt, yielding a net cash position of $608.8M. The company maintains solid liquidity with a current ratio of 9.83 and a debt-to-equity ratio of 0.05 on shareholders' equity of $1.51B. Cash flow operations remained negative in FY2025, with operating cash flow at -$232.9M and free cash flow at -$234.3M, which included capital expenditures of $1.4M. Over the trailing 5-year period, share count changed by 91.0%.
Valuation and performance
Kymera trades at a price-to-sales multiple of 82.1x and an enterprise value to revenue multiple of 85.6x, compared to the median of its US-listed Healthcare peers at 4.1x price-to-sales. Its price-to-book ratio is 6.4x, supported by a market capitalization of $8.62B and an enterprise value of $8.98B. The stock delivered a 1-year return of 73.3%, outperforming the S&P 500 (SPY) return of 16.8%. Over a 5-year horizon, Kymera's return of 83.2% closely tracked the S&P 500 (SPY) return of 83.0%.
What analysts expect
Wall Street sentiment includes 17 Strong Buy, 5 Buy, and 2 Hold ratings, with no Sell or Strong Sell ratings. The mean price target is $139.35, representing a 33.0% upside compared to the last close of $104.78. For the current fiscal year ending December 31, 2026, analysts estimate revenue of $104.8M and an EPS of -$3.85. For the next fiscal year, 21 analysts estimate revenue of $40.7M and an EPS of -$5.10. Kymera beat EPS estimates in 2 of the last 4 quarters, with next earnings scheduled for November 3, 2026.
Key risks and what to watch
- Ongoing losses could strain finances as R&D expense reached $316.6M in FY2025 while trailing twelve months net margin stood at -285.3%.
- Analyst projections include a revenue growth estimate of -61.2% in the next fiscal year, with revenue projected at $40.7M.
- The stock carries elevated volatility with a beta of 1.98 and a short interest of 15.3% of the float.
- Significant past equity issuance is reflected in a 91.0% change in share count over the 5-year period ending in FY2025.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this KYMR AI stock analysis
This page is an AI-written research summary of Kymera Therapeutics, Inc. (KYMR). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: KYMR income statement, KYMR balance sheet, KYMR key metrics, KYMR analyst forecast, KYMR chart. See the KYMR stock overview for the latest quote and news.
KYMR AI stock analysis FAQ
What is Kymera Therapeutics' core drug development focus?
Kymera Therapeutics develops small molecule therapeutics that selectively degrade disease-causing proteins via the body's natural degradation system. Key clinical and preclinical programs include IRAK4 for immunology-inflammation diseases, IRAKIMiD for lymphoma, STAT3, and MDM2.
Does Kymera Therapeutics pay a dividend?
Kymera Therapeutics does not pay a dividend, as the company allocates its financial resources toward research and clinical development.
What are analysts' price targets and expectations for KYMR stock?
Analysts maintain a mean price target of $139.35, which sits 33.0% above the last close of $104.78. Across 21 analysts covering the next fiscal year, expectations project revenue of $40.7M and an EPS of -$5.10.
How strong is Kymera Therapeutics' balance sheet?
As of June 30, 2026, the company held $691.0M in cash and short-term investments against $82.2M in total debt, resulting in net cash of $608.8M. It also maintained a current ratio of 9.83 and shareholders' equity of $1.51B.
When is Kymera Therapeutics scheduled to report earnings?
Kymera's next earnings date is scheduled for November 3, 2026.