Protagonist Therapeutics, Inc. (PTGX) Stock

NASDAQ: PTGXClinical-stage biopharmaceutical company developing peptide-based therapeutics for gastrointestinal diseases.

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Protagonist Therapeutics revenue & net income

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Protagonist Therapeutics annual financials

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Protagonist Therapeutics, Inc. revenue, net income and EPS by fiscal year
Fiscal yearRevenueNet incomeEPS
FY2025$46.0M-$130.1M-$2.05
FY2024$434.4M$275.2M$4.20
FY2023$60.0M-$79.0M-$1.49
FY2022$26.6M-$123.4M-$2.60
FY2021$27.4M-$125.6M-$2.70

Fiscal year ending December 31. Source: company filings via EODHD.

About Protagonist Therapeutics, Inc.

Protagonist Therapeutics, Inc., a dynamic biopharmaceutical firm headquartered in Newark, California, specializes in the discovery and development of peptide-based therapeutic drugs targeting hematology, blood disorders, inflammatory diseases, and immunomodulatory conditions. The company's innovative pipeline includes rusfertide (PTG-300), an injectable hepcidin mimetic currently undergoing Phase II clinical trials. Rusfertide shows promise for treating polycythemia vera, hereditary hemochromatosis, and other blood-related disorders.

Founded in 2006, Protagonist Therapeutics is advancing PN-943, an oral alpha-4-beta-7 integrin-specific antagonist peptide, through Phase II trials for the treatment of inflammatory bowel disease (IBD). Additionally, the company is developing PN-235, an orally delivered interleukin-23 receptor-specific antagonist targeting both IBD and non-IBD indications. These innovative therapies reflect Protagonist Therapeutics' commitment to addressing critical unmet medical needs through cutting-edge peptide technology.

Protagonist Therapeutics operates under a collaborative framework, exemplified by its strategic partnership with Janssen Biotech, Inc., enhancing its capabilities in research, development, and commercialization. This collaboration underscores Protagonist Therapeutics' dedication to leveraging strategic alliances to advance novel therapeutic solutions.

With a strong focus on scientific rigor and innovation, Protagonist Therapeutics continues to expand its footprint in the biopharmaceutical industry. By pushing the boundaries of peptide-based drug development and fostering collaborative partnerships, the company aims to deliver transformative therapies that improve outcomes for patients worldwide.

Protagonist Therapeutics stock FAQ

What is the Protagonist Therapeutics stock ticker symbol?

Protagonist Therapeutics, Inc. trades on the NASDAQ under the ticker symbol PTGX.

What sector and industry is Protagonist Therapeutics in?

Protagonist Therapeutics, Inc. is classified in the Healthcare sector, Biotechnology industry.

How many employees does Protagonist Therapeutics have?

Protagonist Therapeutics, Inc. has about 141 full-time employees.

What were Protagonist Therapeutics's revenue and earnings last fiscal year?

Protagonist Therapeutics reported revenue of $46.0M and net income of -$130.1M in fiscal 2025, with earnings per share of -$2.05. Revenue declined 89.4% from the prior year.

Is Protagonist Therapeutics in the S&P SmallCap 600?

Yes. Protagonist Therapeutics, Inc. (PTGX) is a component of the S&P SmallCap 600, the benchmark index of profitable U.S. small-cap stocks.

Is Protagonist Therapeutics in the Russell 2000?

Yes. Protagonist Therapeutics, Inc. (PTGX) is a component of the Russell 2000, the benchmark index of U.S. small-cap stocks.

When did Protagonist Therapeutics go public?

Protagonist Therapeutics stock began trading on August 11, 2016.

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