Invesco Nasdaq Biotechnology ETF (IBBQ) Holdings
IBBQ holdings summary
as of Oct 25, 2026- Holdings
- 246 positions listed
- Top 10 weight
- 47.1% of net assets
- Effective holdings
- 30 equal-weight equivalent
- Largest holding
- GILD 8.65% Gilead Sciences, Inc.
- Annual turnover
- 13.5% of the portfolio traded
Top 1047.1%
Top 2566.0%
Top 5080.4%
Top 10092.4%
All IBBQ holdings
245 holdings
| # | Name | ||||||
|---|---|---|---|---|---|---|---|
| 1 | GILD | Gilead Sciences, Inc. | Healthcare | 8.65% | $9.9M | $193.67B | — |
| 2 | AMGN | Amgen Inc. | Healthcare | 8.42% | $9.6M | $233.82B | 26.9 |
| 3 | VRTX | Vertex Pharmaceuticals Incorporated | Healthcare | 7.84% | $8.9M | $126.66B | 28.9 |
| 4 | REGN | Regeneron Pharmaceuticals, Inc. | Healthcare | 5.22% | $5.9M | $81.41B | 19.6 |
| 5 | MRNA | Moderna, Inc. | Healthcare | 5.20% | $5.9M | $87.04B | — |
| 6 | ILMN | Illumina, Inc. | Healthcare | 2.74% | $3.1M | $39.64B | 49.0 |
| 7 | RVMD | Revolution Medicines, Inc. | Healthcare | 2.62% | $3.0M | $38.14B | — |
| 8 | BIIB | Biogen Inc. | Healthcare | 2.49% | $2.8M | $34.37B | 41.3 |
| 9 | ALNY | Alnylam Pharmaceuticals, Inc. | Healthcare | 2.08% | $2.4M | $31.02B | 39.1 |
| 10 | RPRX | Royalty Pharma plc | Healthcare | 1.86% | $2.1M | $35.22B | 32.4 |
| 11 | ROIV | Roivant Sciences Ltd. | Healthcare | 1.73% | $2.0M | $24.22B | — |
| 12 | UTHR | United Therapeutics Corporation | Healthcare | 1.65% | $1.9M | $22.87B | 19.1 |
| 13 | ARGX | argenx SE | Healthcare | 1.60% | $1.8M | $51.51B | 31.2 |
| 14 | GH | Guardant Health, Inc. | Healthcare | 1.58% | $1.8M | $21.28B | — |
| 15 | INCY | Incyte Corporation | Healthcare | 1.53% | $1.7M | $22.92B | 14.4 |
| 16 | VTRS | Viatris Inc. | Healthcare | 1.38% | $1.6M | $21.43B | — |
| 17 | INSM | Insmed Incorporated | Healthcare | 1.38% | $1.6M | $21.02B | — |
| 18 | MEDP | Medpace Holdings, Inc. | Healthcare | 1.29% | $1.5M | $17.26B | 36.3 |
| 19 | EXEL | Exelixis, Inc. | Healthcare | 1.03% | $1.2M | $15.42B | 19.6 |
| 20 | NBIX | Neurocrine Biosciences, Inc. | Healthcare | 0.99% | $1.1M | $13.79B | 19.9 |
| 21 | ASND | Ascendis Pharma A/S | Healthcare | 0.97% | $1.1M | $14.82B | 17.3 |
| 22 | HALO | Halozyme Therapeutics, Inc. | Healthcare | 0.97% | $1.1M | $13.83B | 35.6 |
| 23 | JAZZ | Jazz Pharmaceuticals plc | Healthcare | 0.96% | $1.1M | $13.65B | 14.4 |
| 24 | BBIO | BridgeBio Pharma, Inc. | Healthcare | 0.95% | $1.1M | $12.98B | — |
| 25 | ONC | BeiGene, Ltd. | Healthcare | 0.91% | $1.0M | $41.99B | 66.0 |
| 26 | SMMT | Summit Therapeutics Inc. | Healthcare | 0.84% | $959,561.88 | $11.67B | — |
| 27 | TEM | Tempus AI, Inc. | Healthcare | 0.76% | $871,490.00 | $11.68B | — |
| 28 | BMRN | BioMarin Pharmaceutical Inc. | Healthcare | 0.72% | $817,826.54 | $10.58B | 147.8 |
| 29 | MDGL | Madrigal Pharmaceuticals, Inc. | Healthcare | 0.69% | $780,911.55 | $10.39B | — |
| 30 | BNTX | BioNTech SE | Healthcare | 0.68% | $774,531.18 | $22.03B | — |
| 31 | PCVX | Vaxcyte, Inc. | Healthcare | 0.62% | $709,588.15 | $10.01B | — |
| 32 | SNY | Sanofi | Healthcare | 0.62% | $709,474.21 | $97.31B | 21.4 |
| 33 | PTGX | Protagonist Therapeutics, Inc. | Healthcare | 0.61% | $696,257.73 | $8.33B | 125.0 |
| 34 | TWST | Twist Bioscience Corporation | Healthcare | 0.61% | $690,333.10 | $8.80B | — |
| 35 | KRYS | Krystal Biotech, Inc. | Healthcare | 0.61% | $690,105.23 | $9.37B | 39.7 |
| 36 | TXG | 10x Genomics, Inc. | Healthcare | 0.59% | $677,686.30 | $9.10B | — |
| 37 | KYMR | Kymera Therapeutics, Inc. | Healthcare | 0.59% | $670,964.13 | $8.62B | — |
| 38 | CAI | Caris Life Sciences, Inc. | Healthcare | 0.57% | $654,557.47 | $8.64B | 18.1 |
| 39 | CYTK | Cytokinetics, Incorporated | Healthcare | 0.57% | $645,214.78 | $8.61B | — |
| 40 | NK | NantKwest Inc | Healthcare | 0.55% | $630,175.34 | — | — |
| 41 | ARWR | Arrowhead Pharmaceuticals, Inc. | Healthcare | 0.55% | $622,541.69 | $7.90B | — |
| 42 | SYRE | Spyre Therapeutics, Inc. | Healthcare | 0.54% | $620,490.85 | $7.47B | — |
| 43 | AXSM | Axsome Therapeutics, Inc. | Healthcare | 0.52% | $596,336.60 | $8.23B | — |
| 44 | ALKS | Alkermes plc | Healthcare | 0.51% | $581,297.16 | $6.92B | 108.5 |
| 45 | IONS | Ionis Pharmaceuticals, Inc. | Healthcare | 0.47% | $539,369.02 | $7.14B | — |
| 46 | AMRX | Amneal Pharmaceuticals, Inc. | Healthcare | 0.46% | $529,114.86 | $6.68B | 39.1 |
| 47 | PRAX | Praxis Precision Medicines, Inc. | Healthcare | 0.45% | $509,859.82 | $6.75B | — |
| 48 | IOVA | Iovance Biotherapeutics, Inc. | Healthcare | 0.42% | $479,553.07 | $6.17B | — |
| 49 | GRAL | GRAIL, Inc. | Healthcare | 0.41% | $467,020.20 | $5.26B | — |
| 50 | RYTM | Rhythm Pharmaceuticals, Inc. | Healthcare | 0.41% | $466,108.72 | $5.91B | — |
| 51 | LGND | Ligand Pharmaceuticals Incorporated | Healthcare | 0.40% | $457,221.78 | $5.89B | 31.1 |
| 52 | IMVT | Immunovant, Inc. | Healthcare | 0.38% | $436,827.38 | $5.52B | — |
| 53 | KOD | Kodiak Sciences Inc. | Healthcare | 0.38% | $429,535.53 | $5.39B | — |
| 54 | CGON | CG Oncology, Inc. | Healthcare | 0.38% | $428,168.31 | $5.31B | — |
| 55 | COGT | Cogent Biosciences, Inc. | Healthcare | 0.37% | $426,003.54 | $5.12B | — |
| 56 | MIRM | Mirum Pharmaceuticals, Inc. | Healthcare | 0.36% | $409,938.69 | $5.20B | — |
| 57 | ERAS | Erasca, Inc. | Healthcare | 0.35% | $395,127.12 | $4.68B | — |
| 58 | AAVXF | ABIVAX Société Anonyme | Healthcare | 0.35% | $393,873.83 | — | — |
| 59 | ORKA | Oruka Therapeutics, Inc. | Healthcare | 0.34% | $388,860.68 | $4.76B | — |
| 60 | TVTX | Travere Therapeutics, Inc. | Healthcare | 0.33% | $377,125.36 | $4.61B | — |
| 61 | CRSP | CRISPR Therapeutics AG | Healthcare | 0.33% | $375,530.27 | $4.76B | — |
| 62 | SRRK | Scholar Rock Holding Corporation | Healthcare | 0.33% | $374,618.79 | $4.86B | — |
| 63 | PTCT | PTC Therapeutics, Inc. | Healthcare | 0.33% | $370,403.19 | $4.94B | — |
| 64 | DFTX | Definium Therapeutics, Inc. | Healthcare | 0.31% | $348,413.70 | $4.31B | — |
| 65 | GMAB | Genmab A/S | Healthcare | 0.29% | $324,829.13 | $22.75B | 29.1 |
| 66 | ADPT | Adaptive Biotechnologies Corporation | Healthcare | 0.28% | $316,056.12 | $3.83B | — |
| 67 | ARQT | Arcutis Biotherapeutics, Inc. | Healthcare | 0.27% | $310,473.30 | $3.62B | 131.0 |
| 68 | EWTX | Edgewise Therapeutics, Inc. | Healthcare | 0.27% | $307,852.79 | $4.04B | — |
| 69 | INDV | Indivior PLC | Healthcare | 0.27% | $302,839.64 | $3.83B | 11.6 |
| 70 | ABCL | AbCellera Biologics Inc. | Healthcare | 0.26% | $300,902.74 | $3.82B | — |
| 71 | RLAY | Relay Therapeutics, Inc. | Healthcare | 0.26% | $291,446.13 | $3.57B | — |
| 72 | BCTG | BCTG Acquisition Corp | Financial Services | 0.25% | $288,369.88 | — | — |
| 73 | VCYT | Veracyte, Inc. | Healthcare | 0.25% | $286,319.04 | $3.47B | 30.8 |
| 74 | KNSA | Kiniksa Pharmaceuticals, Ltd. | Healthcare | 0.24% | $268,317.29 | $6.13B | 79.4 |
| 75 | IDYA | IDEAYA Biosciences, Inc. | Healthcare | 0.22% | $247,353.22 | $3.17B | — |
| 76 | AMLX | Amylyx Pharmaceuticals, Inc. | Healthcare | 0.22% | $246,669.61 | $3.31B | — |
| 77 | XENE | Xenon Pharmaceuticals Inc. | Healthcare | 0.22% | $246,555.68 | $3.24B | — |
| 78 | ACAD | ACADIA Pharmaceuticals Inc. | Healthcare | 0.22% | $245,530.26 | $3.29B | 8.6 |
| 79 | TARS | Tarsus Pharmaceuticals, Inc. | Healthcare | 0.21% | $235,162.16 | $3.19B | — |
| 80 | ELVN | Enliven Therapeutics, Inc. | Healthcare | 0.20% | $229,465.40 | $2.73B | — |
| 81 | DYN | Dyne Therapeutics, Inc. | Healthcare | 0.19% | $219,211.24 | $2.66B | — |
| 82 | DNLI | Denali Therapeutics Inc. | Healthcare | 0.19% | $216,932.54 | $2.81B | — |
| 83 | IRON | Disc Medicine, Inc. | Healthcare | 0.19% | $214,539.90 | $2.18B | — |
| 84 | NRIX | Nurix Therapeutics, Inc. | Healthcare | 0.17% | $193,917.63 | $2.67B | 10.0 |
| 85 | KH6_old | KINGHERO | Other | 0.16% | $187,765.14 | — | — |
| 86 | SUPN | Supernus Pharmaceuticals, Inc. | Healthcare | 0.16% | $187,081.52 | $2.21B | — |
| 87 | ADMA | ADMA Biologics, Inc. | Healthcare | 0.16% | $186,853.65 | $2.39B | 15.3 |
| 88 | BEAM | Beam Therapeutics Inc. | Healthcare | 0.16% | $186,056.11 | $2.42B | — |
| 89 | FTRE | Fortrea Holdings Inc. | Healthcare | 0.15% | $175,460.14 | $2.14B | — |
| 90 | AUP | Aurinia Pharmaceuticals Inc | Technology | 0.15% | $175,004.40 | — | — |
| 91 | AGIO | Agios Pharmaceuticals, Inc. | Healthcare | 0.15% | $172,839.63 | $1.87B | — |
| 92 | MBX | MBX Biosciences, Inc. | Healthcare | 0.15% | $172,042.08 | $2.39B | — |
| 93 | PGEN | Precigen, Inc. | Healthcare | 0.15% | $170,674.86 | $2.28B | — |
| 94 | PHVS | Pharvaris N.V. | Healthcare | 0.15% | $170,333.06 | $1.95B | — |
| 95 | VCEL | Vericel Corporation | Healthcare | 0.15% | $167,256.81 | $2.05B | 85.4 |
| 96 | VERA | Vera Therapeutics, Inc. | Healthcare | 0.14% | $155,863.29 | $2.01B | — |
| 97 | BCRX | BioCryst Pharmaceuticals, Inc. | Healthcare | 0.14% | $154,268.20 | $1.99B | — |
| 98 | HRMY | Harmony Biosciences Holdings, Inc. | Healthcare | 0.13% | $151,647.69 | $2.21B | 12.2 |
| 99 | RXRX | Recursion Pharmaceuticals, Inc. | Healthcare | 0.13% | $147,318.16 | $1.86B | — |
| 100 | SEPN | Septerna, Inc. | Healthcare | 0.13% | $146,292.74 | $1.70B | — |
| 101 | ZA8 | ZYMEWORKS DL-00001 | Healthcare | 0.13% | $146,178.80 | — | — |
| 102 | MLYS | Mineralys Therapeutics, Inc. | Healthcare | 0.13% | $142,532.88 | $1.79B | — |
| 103 | TRVI | Trevi Therapeutics, Inc. | Healthcare | 0.12% | $141,279.59 | $1.69B | — |
| 104 | SRPT | Sarepta Therapeutics, Inc. | Healthcare | 0.12% | $136,722.19 | $1.81B | — |
| 105 | VIR | Vir Biotechnology, Inc. | Healthcare | 0.12% | $136,608.25 | $1.69B | — |
| 106 | XNCR | Xencor, Inc. | Healthcare | 0.12% | $136,380.38 | $1.70B | — |
| 107 | XERS | Xeris Biopharma Holdings, Inc. | Healthcare | 0.12% | $136,038.58 | $1.88B | — |
| 108 | LEGN | Legend Biotech Corporation | Healthcare | 0.12% | $134,785.29 | $3.59B | — |
| 109 | ZBIO | Zenas BioPharma, Inc. | Healthcare | 0.12% | $133,304.13 | $1.62B | — |
| 110 | GPCR | Structure Therapeutics Inc. | Healthcare | 0.11% | $130,683.62 | $1.50B | — |
| 111 | ANIP | ANI Pharmaceuticals, Inc. | Healthcare | 0.11% | $130,000.01 | $1.66B | 15.6 |
| 112 | MAZE | Maze Therapeutics, Inc. | Healthcare | 0.11% | $129,316.40 | $1.53B | — |
| 113 | NVCR | NovoCure Limited | Healthcare | 0.11% | $127,379.50 | $1.64B | — |
| 114 | URGN | UroGen Pharma Ltd. | Healthcare | 0.11% | $125,214.74 | $1.69B | — |
| 115 | NVAX | Novavax, Inc. | Healthcare | 0.11% | $124,303.25 | $1.86B | — |
| 116 | PSNL | Personalis, Inc. | Healthcare | 0.11% | $122,594.23 | $1.67B | — |
| 117 | STOK | Stoke Therapeutics, Inc. | Healthcare | 0.11% | $122,366.36 | $1.56B | — |
| 118 | ABSI | Absci Corporation | Healthcare | 0.11% | $121,340.94 | $1.42B | — |
| 119 | NTLA | Intellia Therapeutics, Inc. | Healthcare | 0.11% | $121,113.07 | $1.60B | — |
| 120 | TRAX | First Tracks Biotherapeutics | Healthcare | 0.11% | $120,429.46 | $1.23B | — |
| 121 | QURE | uniQure N.V. | Healthcare | 0.10% | $117,581.08 | $1.51B | — |
| 122 | ALVO | Alvotech | Healthcare | 0.10% | $116,099.92 | — | — |
| 123 | CMPS | COMPASS Pathways plc | Healthcare | 0.10% | $115,530.25 | $1.49B | — |
| 124 | RARE | Ultragenyx Pharmaceutical Inc. | Healthcare | 0.10% | $115,416.31 | $1.43B | — |
| 125 | INVA | Innoviva, Inc. | Healthcare | 0.10% | $115,302.38 | $1.50B | 4.9 |
| 126 | PCRX | Pacira BioSciences, Inc. | Healthcare | 0.10% | $115,074.51 | $1.45B | 103.8 |
| 127 | OCUL | Ocular Therapeutix, Inc. | Healthcare | 0.10% | $112,340.06 | $1.51B | — |
| 128 | ORIC | ORIC Pharmaceuticals, Inc. | Healthcare | 0.09% | $107,212.98 | $1.28B | — |
| 129 | ANAB | AnaptysBio, Inc. | Healthcare | 0.09% | $106,985.11 | $1.39B | — |
| 130 | INBX | Inhibrx, Inc. | Healthcare | 0.09% | $106,643.31 | $1.32B | — |
| 131 | ETON | Eton Pharmaceuticals, Inc. | Healthcare | 0.09% | $106,415.43 | $1.44B | 125.8 |
| 132 | IMCR | Immunocore Holdings plc | Healthcare | 0.09% | $106,301.50 | $1.51B | — |
| 133 | RAPP | Rapport Therapeutics, Inc. | Healthcare | 0.08% | $96,275.21 | $1.32B | — |
| 134 | TYRA_old | TYRA | Healthcare | 0.08% | $94,794.05 | — | — |
| 135 | TSHA | Taysha Gene Therapies, Inc. | Healthcare | 0.08% | $94,224.37 | $1.18B | — |
| 136 | GHRS | GH Research PLC | Healthcare | 0.08% | $92,515.35 | $1.25B | — |
| 137 | OMER | Omeros Corporation | Healthcare | 0.08% | $92,173.54 | $1.17B | 13.3 |
| 138 | SNDX | Syndax Pharmaceuticals, Inc. | Healthcare | 0.08% | $91,945.67 | $1.15B | — |
| 139 | BCAX | Bicara Therapeutics Inc. | Healthcare | 0.07% | $81,805.44 | $1.11B | — |
| 140 | AMPH | Amphastar Pharmaceuticals, Inc. | Healthcare | 0.07% | $81,691.51 | $1.10B | 15.3 |
| 141 | MRVI | Maravai LifeSciences Holdings, Inc. | Healthcare | 0.07% | $81,349.70 | $2.51B | — |
| 142 | ZLAB | Zai Lab Limited | Healthcare | 0.07% | $81,235.77 | $2.60B | — |
| 143 | VOR | Vor Biopharma Inc. | Healthcare | 0.07% | $79,982.48 | $977.0M | 0.1 |
| 144 | REPL | Replimune Group, Inc. | Healthcare | 0.07% | $79,754.61 | $1.02B | — |
| 145 | HROW | Harrow Health, Inc. | Healthcare | 0.07% | $79,071.00 | $1.02B | — |
| 146 | MNKD | MannKind Corporation | Healthcare | 0.07% | $77,589.84 | $977.5M | — |
| 147 | JANX | Janux Therapeutics, Inc. | Healthcare | 0.07% | $77,475.91 | $1.01B | — |
| 148 | CSTL | Castle Biosciences, Inc. | Healthcare | 0.07% | $76,792.29 | $976.4M | — |
| 149 | AVBP | ArriVent BioPharma, Inc. | Healthcare | 0.07% | $75,652.94 | $821.5M | — |
| 150 | SLN | Silence Therapeutics plc | Healthcare | 0.06% | $73,032.43 | $539.5M | — |
| 151 | CGEM | Cullinan Oncology, Inc. | Healthcare | 0.06% | $72,120.95 | $794.7M | — |
| 152 | GLUE | Monte Rosa Therapeutics, Inc. | Healthcare | 0.06% | $72,120.95 | $831.0M | — |
| 153 | CRVS | Corvus Pharmaceuticals, Inc. | Healthcare | 0.06% | $70,070.12 | $800.8M | — |
| 154 | GRFS | Grifols, S.A. | Healthcare | 0.06% | $67,791.42 | $5.20B | 9.9 |
| 155 | KURA | Kura Oncology, Inc. | Healthcare | 0.06% | $67,449.61 | $807.8M | — |
| 156 | PAHC | Phibro Animal Health Corporation | Healthcare | 0.06% | $65,512.71 | $1.58B | 16.0 |
| 157 | RIGL | Rigel Pharmaceuticals, Inc. | Healthcare | 0.06% | $64,145.49 | $858.7M | 2.7 |
| 158 | MGTX | MeiraGTx Holdings plc | Healthcare | 0.06% | $63,917.62 | $891.3M | 10.7 |
| 159 | ALMS | Alumis Inc. | Healthcare | 0.06% | $63,689.75 | $792.1M | — |
| 160 | SVRA | Savara Inc. | Healthcare | 0.06% | $63,461.88 | $914.3M | — |
| 161 | TKM | Arbutus Biopharma Corp | Other | 0.05% | $60,727.44 | — | — |
| 162 | ARDX | Ardelyx, Inc. | Healthcare | 0.05% | $60,043.83 | $797.8M | — |
| 163 | COLL | Collegium Pharmaceutical, Inc. | Healthcare | 0.05% | $58,676.60 | $755.0M | 18.3 |
| 164 | ANNX | Annexon, Inc. | Healthcare | 0.05% | $56,625.77 | $646.5M | — |
| 165 | GERN | Geron Corporation | Healthcare | 0.05% | $55,828.23 | $751.7M | — |
| 166 | SANA | Sana Biotechnology, Inc. | Healthcare | 0.05% | $54,574.94 | $679.5M | — |
| 167 | PRME | Prime Medicine, Inc. | Healthcare | 0.05% | $51,612.63 | $629.4M | — |
| 168 | AURA | Aura Biosciences, Inc. | Healthcare | 0.05% | $51,498.69 | $632.6M | — |
| 169 | MESO | Mesoblast Limited | Healthcare | 0.04% | $51,156.88 | $1.72B | — |
| 170 | DSGN | Design Therapeutics, Inc. | Healthcare | 0.04% | $51,156.88 | $645.2M | — |
| 171 | SLDB | Solid Biosciences Inc. | Healthcare | 0.04% | $50,131.47 | $593.0M | — |
| 172 | OABI | OmniAb, Inc. | Healthcare | 0.04% | $49,333.92 | $667.3M | — |
| 173 | WVE | Wave Life Sciences Ltd. | Healthcare | 0.04% | $47,624.89 | $616.8M | — |
| 174 | PACB | Pacific Biosciences of California, Inc. | Healthcare | 0.04% | $47,510.96 | $537.7M | — |
| 175 | CADL | Candel Therapeutics, Inc. | Healthcare | 0.04% | $47,397.02 | $626.7M | — |
| 176 | CRMD | CorMedix Inc. | Healthcare | 0.04% | $47,055.22 | $565.9M | 3.5 |
| 177 | SGMT | Sagimet Biosciences Inc. | Healthcare | 0.04% | $47,055.22 | $568.7M | — |
| 178 | FDMT | 4D Molecular Therapeutics, Inc. | Healthcare | 0.04% | $46,941.28 | $670.7M | — |
| 179 | AGPXX | Invesco Short-Term Investments Trust Government & Agency Portfolio Institutional | Other | 0.04% | $45,688.00 | — | — |
| 180 | PBYI | Puma Biotechnology, Inc. | Healthcare | 0.04% | $45,232.26 | $507.4M | 19.3 |
| 181 | KMPH | KemPharm Inc | Healthcare | 0.04% | $44,662.58 | — | — |
| 182 | IRWD | Ironwood Pharmaceuticals, Inc. | Healthcare | 0.04% | $43,637.16 | $578.3M | 4.5 |
| 183 | OLMA | Olema Pharmaceuticals, Inc. | Healthcare | 0.04% | $40,333.04 | $575.7M | — |
| 184 | ACRS | Aclaris Therapeutics, Inc. | Healthcare | 0.04% | $39,991.24 | $482.8M | — |
| 185 | CTMX | CytomX Therapeutics, Inc. | Healthcare | 0.03% | $38,168.28 | $496.8M | — |
| 186 | AQST | Aquestive Therapeutics, Inc. | Healthcare | 0.03% | $37,940.41 | $474.4M | — |
| 187 | GLPG | Galapagos NV ADR | Healthcare | 0.03% | $37,484.67 | — | — |
| 188 | PHAT | Phathom Pharmaceuticals, Inc. | Healthcare | 0.03% | $36,117.44 | $559.8M | — |
| 189 | EOLS | Evolus, Inc. | Healthcare | 0.03% | $36,117.44 | $469.0M | — |
| 190 | KMDA | Kamada | Healthcare | 0.03% | $35,547.77 | — | — |
| 191 | ARVN | Arvinas, Inc. | Healthcare | 0.03% | $34,978.09 | $449.7M | 26.8 |
| 192 | NGNE | Neurogene Inc. | Healthcare | 0.03% | $34,978.09 | $465.3M | — |
| 193 | ALT | Altimmune, Inc. | Healthcare | 0.03% | $32,699.39 | $427.9M | — |
| 194 | PRTA | Prothena Corporation plc | Healthcare | 0.03% | $32,357.58 | $428.7M | — |
| 195 | RGNX | REGENXBIO Inc. | Healthcare | 0.03% | $31,901.84 | $457.1M | — |
| 196 | SPRY | ARS Pharmaceuticals, Inc. | Healthcare | 0.03% | $31,787.91 | $399.8M | — |
| 197 | ALLO | Allogene Therapeutics, Inc. | Healthcare | 0.03% | $31,332.17 | $452.6M | — |
| 198 | EDIT | Editas Medicine, Inc. | Healthcare | 0.03% | $29,281.33 | $360.9M | — |
| 199 | TECX | Tectonic Therapeutic Inc. | Healthcare | 0.03% | $28,597.72 | $403.7M | — |
| 200 | CCCC | C4 Therapeutics, Inc. | Healthcare | 0.02% | $28,369.85 | $340.2M | — |
| 201 | TKNO | Alpha Teknova, Inc. | Healthcare | 0.02% | $26,319.02 | $380.1M | — |
| 202 | ENTA | Enanta Pharmaceuticals, Inc. | Healthcare | 0.02% | $25,635.41 | $323.3M | — |
| 203 | OBIO | Orchestra BioMed Holdings, Inc. | Healthcare | 0.02% | $25,293.60 | $327.6M | — |
| 204 | AVIR | Atea Pharmaceuticals, Inc. | Healthcare | 0.02% | $25,293.60 | $346.5M | — |
| 205 | KYTX | Kyverna Therapeutics, Inc. | Healthcare | 0.02% | $25,065.73 | $350.7M | — |
| 206 | AUTL | Autolus Therapeutics plc | Healthcare | 0.02% | $24,040.32 | $425.9M | — |
| 207 | ARCT | Arcturus Therapeutics Holdings Inc. | Healthcare | 0.02% | $20,736.20 | $293.9M | — |
| 208 | FULC | Fulcrum Therapeutics, Inc. | Healthcare | 0.02% | $20,508.33 | $278.8M | — |
| 209 | CTNM | Contineum Therapeutics, Inc. | Healthcare | 0.02% | $20,166.52 | $266.4M | — |
| 210 | QSI | Quantum-Si incorporated | Healthcare | 0.02% | $19,938.65 | $245.1M | — |
| 211 | RCKT | Rocket Pharmaceuticals, Inc. | Healthcare | 0.02% | $18,229.62 | $239.3M | — |
| 212 | ACIU | AC Immune SA | Healthcare | 0.02% | $17,773.88 | $237.6M | — |
| 213 | LRMR | Larimar Therapeutics, Inc. | Healthcare | 0.02% | $17,659.95 | $206.2M | — |
| 214 | CABA | Cabaletta Bio, Inc. | Healthcare | 0.02% | $17,659.95 | $239.1M | — |
| 215 | VNDA | Vanda Pharmaceuticals Inc. | Healthcare | 0.02% | $17,546.01 | $243.7M | — |
| 216 | IMRX | Immuneering Corporation | Healthcare | 0.02% | $17,546.01 | $232.3M | — |
| 217 | LNDC | Landec Corporation | Healthcare | 0.02% | $17,432.08 | — | — |
| 218 | BIOA | BioAge Labs, Inc | Healthcare | 0.02% | $17,318.14 | $222.1M | — |
| 219 | KROS | Keros Therapeutics, Inc. | Healthcare | 0.01% | $17,090.27 | $211.4M | — |
| 220 | LXEO | Lexeo Therapeutics, Inc. | Healthcare | 0.01% | $16,976.34 | $216.7M | — |
| 221 | SIGA | SIGA Technologies, Inc. | Healthcare | 0.01% | $16,862.40 | $227.8M | — |
| 222 | LYEL | Lyell Immunopharma, Inc. | Healthcare | 0.01% | $16,520.60 | $199.0M | — |
| 223 | ADGI | Adagio Therapeutics Inc | Healthcare | 0.01% | $14,355.83 | — | — |
| 224 | PEPG | PepGen Inc. | Healthcare | 0.01% | $13,900.09 | $179.8M | — |
| 225 | TRDA | Entrada Therapeutics, Inc. | Healthcare | 0.01% | $13,672.22 | $170.2M | — |
| 226 | BCYC | Bicycle Therapeutics plc | Healthcare | 0.01% | $12,077.13 | $241.5M | — |
| 227 | SION | Sionna Therapeutics, Inc. | Healthcare | 0.01% | $11,849.26 | $175.6M | — |
| 228 | IMAB | I-Mab | Healthcare | 0.01% | $11,507.45 | — | — |
| 229 | CHRS | Coherus BioSciences, Inc. | Healthcare | 0.01% | $11,393.52 | $153.0M | — |
| 230 | UPB | Upstream Bio, Inc. | Healthcare | 0.01% | $11,393.52 | $151.2M | — |
| 231 | CDXS | Codexis, Inc. | Healthcare | 0.01% | $10,254.16 | $135.8M | — |
| 232 | PYXS | Pyxis Oncology, Inc. | Healthcare | 0.01% | $10,254.16 | $200.7M | — |
| 233 | MENS | Jyong Biotech Ltd. | Healthcare | 0.01% | $9,684.49 | $139.9M | — |
| 234 | AVXL | Anavex Life Sciences Corp. | Healthcare | 0.01% | $9,000.88 | $121.4M | — |
| 235 | HUMA | Humacyte, Inc. | Healthcare | 0.01% | $8,886.94 | $119.2M | — |
| 236 | FHTX | Foghorn Therapeutics Inc. | Healthcare | 0.01% | $8,773.01 | $109.9M | — |
| 237 | BDTX | Black Diamond Therapeutics, Inc. | Healthcare | 0.01% | $8,317.27 | $98.8M | — |
| 238 | VYGR | Voyager Therapeutics, Inc. | Healthcare | 0.01% | $8,203.33 | $117.1M | — |
| 239 | LENZ | LENZ Therapeutics, Inc. | Healthcare | 0.01% | $7,633.66 | $102.7M | — |
| 240 | TNYA | Tenaya Therapeutics, Inc. | Healthcare | 0.01% | $6,494.30 | $85.4M | — |
| 241 | NMRA | Neumora Therapeutics, Inc. | Healthcare | 0.00% | $5,127.08 | $89.0M | — |
| 242 | RANI | Rani Therapeutics Holdings, Inc. | Healthcare | 0.00% | $5,013.15 | $90.0M | — |
| 243 | CRBU | Caribou Biosciences, Inc. | Healthcare | 0.00% | $3,987.73 | $50.4M | — |
| 244 | EYPT | EyePoint Pharmaceuticals, Inc. | Healthcare | 0.00% | $2,620.51 | $250.7M | — |
| 245 | AARD | Aardvark Therapeutics, Inc. | Healthcare | 0.00% | $2,392.64 | $82.7M | — |
Weights as a percentage of net assets. Value held = weight × net assets ($113.9M). Market cap and P/E from each company's latest fundamentals (U.S.-listed stocks).
IBBQ sector breakdown
| Sector | Weight | Holdings | Largest |
|---|---|---|---|
| Healthcare | 99.2% | 240 | GILD, AMGN, VRTX |
| Other | 0.3% | 3 | KH6_old, TKM, AGPXX |
| Financial Services | 0.3% | 1 | BCTG |
| Technology | 0.2% | 1 | AUP |
Sum of the weights of the holdings in each sector.
IBBQ top industries
Biotechnology
63.5%
Drug Manufacturers - General
20.2%
Drug Manufacturers - Specialty & Generic
7.0%
Diagnostics & Research
6.7%
Medical Devices
0.8%
Health Information Services
0.8%
Shell Companies
0.3%
Technical & System Software
0.2%
Medical Care Facilities
0.1%
Pharmaceuticals
0.1%
IBBQ overlap with other ETFs
| ETF | Fund | Overlap | Shared holdings | Expense ratio |
|---|---|---|---|---|
| IBB | iShares Biotechnology ETF | 83.5% | 196 of 234 | 0.46% |
| BIB | ProShares Ultra Nasdaq Biotechnology | 61.2% | 244 of 245 | 0.95% |
| BBH | VanEck Biotech ETF | 57.1% | 19 of 25 | 0.33% |
| BIS | ProShares UltraShort Nasdaq Biotechnology | 51.6% | 55 of 104 | 0.96% |
| PBE | Invesco Dynamic Biotechnology & Genome ETF | 39.8% | 27 of 31 | 0.56% |
| IWM | iShares Russell 2000 ETF | 10.4% | 170 of 1,962 | 0.19% |
Overlap = sum over shared holdings of the smaller of the two weights. 100% means identical portfolios.
About the IBBQ portfolio
Invesco Nasdaq Biotechnology ETF holds 246 positions. The ten largest make up 47.1% of the fund and the top 50 80.4%, so it behaves like a portfolio of about 30 equally weighted stocks. The biggest positions are Gilead Sciences, Inc. (8.65%), Amgen Inc. (8.42%), Vertex Pharmaceuticals Incorporated (7.84%), Regeneron Pharmaceuticals, Inc. (5.22%), Moderna, Inc. (5.20%).
By sector, Healthcare is 99.2%, Other is 0.3%, Financial Services is 0.3%. Holdings data is from the fund's latest portfolio as reported by EODHD on October 25, 2026; positions change as the fund rebalances.
Related: IBBQ chart, IBBQ performance, IBBQ dividends, IBBQ overview.
IBBQ holdings FAQ
How many holdings does IBBQ have?
IBBQ holds 246 positions as of October 25, 2026.
What are the top 10 holdings of IBBQ?
The ten largest holdings are Gilead Sciences, Inc. (8.65%), Amgen Inc. (8.42%), Vertex Pharmaceuticals Incorporated (7.84%), Regeneron Pharmaceuticals, Inc. (5.22%), Moderna, Inc. (5.20%), Illumina, Inc. (2.74%), Revolution Medicines, Inc. (2.62%), Biogen Inc. (2.49%), Alnylam Pharmaceuticals, Inc. (2.08%), Royalty Pharma plc (1.86%). Together they are 47.1% of the fund.
What percentage of IBBQ is Gilead Sciences, Inc.?
Gilead Sciences, Inc. is the largest holding at 8.65% of net assets, about $9.9M of the fund's $113.9M.
Which sector is the largest in IBBQ?
Healthcare is the largest sector at 99.2%, followed by Other (0.3%) and Financial Services (0.3%), based on the sectors of the individual holdings.
How concentrated is IBBQ?
The top 10 holdings are 47.1% of the fund. By the effective number of holdings (1 divided by the sum of squared weights) IBBQ behaves like a portfolio of about 30 equally weighted stocks.