iShares Biotechnology ETF (IBB) Holdings
IBB holdings summary
as of Oct 25, 2026- Holdings
- 236 positions listed
- Top 10 weight
- 51.0% of net assets
- Effective holdings
- 28 equal-weight equivalent
- Largest holding
- AMGN 8.46% Amgen Inc.
- Annual turnover
- 13.5% of the portfolio traded
Top 1051.0%
Top 2571.0%
Top 5084.3%
Top 10094.4%
All IBB holdings
234 holdings
| # | Name | ||||||
|---|---|---|---|---|---|---|---|
| 1 | AMGN | Amgen Inc. | Healthcare | 8.46% | $907.5M | $233.82B | 26.9 |
| 2 | GILD | Gilead Sciences, Inc. | Healthcare | 8.27% | $887.5M | $193.67B | — |
| 3 | VRTX | Vertex Pharmaceuticals Incorporated | Healthcare | 7.82% | $839.0M | $126.66B | 28.9 |
| 4 | REGN | Regeneron Pharmaceuticals, Inc. | Healthcare | 5.97% | $640.4M | $81.41B | 19.6 |
| 5 | MRNA | Moderna, Inc. | Healthcare | 5.12% | $549.4M | $87.04B | — |
| 6 | NTRA | Natera, Inc. | Healthcare | 3.96% | $424.4M | $56.71B | — |
| 7 | ARGX | argenx SE | Healthcare | 3.32% | $355.9M | $51.51B | 31.2 |
| 8 | ILMN | Illumina, Inc. | Healthcare | 2.96% | $318.0M | $39.64B | 49.0 |
| 9 | BIIB | Biogen Inc. | Healthcare | 2.54% | $272.8M | $34.37B | 41.3 |
| 10 | RVMD | Revolution Medicines, Inc. | Healthcare | 2.54% | $272.8M | $38.14B | — |
| 11 | ONC | BeiGene, Ltd. | Healthcare | 2.35% | $252.2M | $41.99B | 66.0 |
| 12 | ALNY | Alnylam Pharmaceuticals, Inc. | Healthcare | 2.04% | $219.1M | $31.02B | 39.1 |
| 13 | UTHR | United Therapeutics Corporation | Healthcare | 1.78% | $190.5M | $22.87B | 19.1 |
| 14 | INCY | Incyte Corporation | Healthcare | 1.67% | $179.1M | $22.92B | 14.4 |
| 15 | GMAB | Genmab A/S | Healthcare | 1.64% | $175.8M | $22.75B | 29.1 |
| 16 | INSM | Insmed Incorporated | Healthcare | 1.49% | $159.5M | $21.02B | — |
| 17 | ROIV | Roivant Sciences Ltd. | Healthcare | 1.32% | $141.1M | $24.22B | — |
| 18 | CRL | Charles River Laboratories International, Inc. | Healthcare | 1.10% | $118.1M | $14.46B | — |
| 19 | EXEL | Exelixis, Inc. | Healthcare | 1.10% | $117.9M | $15.42B | 19.6 |
| 20 | MEDP | Medpace Holdings, Inc. | Healthcare | 1.02% | $109.0M | $17.26B | 36.3 |
| 21 | ASND | Ascendis Pharma A/S | Healthcare | 1.02% | $109.0M | $14.82B | 17.3 |
| 22 | NBIX | Neurocrine Biosciences, Inc. | Healthcare | 0.98% | $105.1M | $13.79B | 19.9 |
| 23 | HALO | Halozyme Therapeutics, Inc. | Healthcare | 0.94% | $100.7M | $13.83B | 35.6 |
| 24 | TECH | Bio-Techne Corporation | Healthcare | 0.81% | $87.1M | $11.38B | 62.6 |
| 25 | BBIO | BridgeBio Pharma, Inc. | Healthcare | 0.80% | $85.8M | $12.98B | — |
| 26 | BMRN | BioMarin Pharmaceutical Inc. | Healthcare | 0.77% | $82.1M | $10.58B | 147.8 |
| 27 | MDGL | Madrigal Pharmaceuticals, Inc. | Healthcare | 0.70% | $75.2M | $10.39B | — |
| 28 | RGEN | Repligen Corporation | Healthcare | 0.67% | $71.6M | $11.14B | 240.3 |
| 29 | PCVX | Vaxcyte, Inc. | Healthcare | 0.63% | $67.6M | $10.01B | — |
| 30 | TWST | Twist Bioscience Corporation | Healthcare | 0.62% | $66.3M | $8.80B | — |
| 31 | BNTX | BioNTech SE | Healthcare | 0.62% | $66.1M | $22.03B | — |
| 32 | CYTK | Cytokinetics, Incorporated | Healthcare | 0.61% | $65.4M | $8.61B | — |
| 33 | KRYS | Krystal Biotech, Inc. | Healthcare | 0.59% | $62.9M | $9.37B | 39.7 |
| 34 | KYMR | Kymera Therapeutics, Inc. | Healthcare | 0.58% | $62.7M | $8.62B | — |
| 35 | PTGX | Protagonist Therapeutics, Inc. | Healthcare | 0.58% | $62.7M | $8.33B | 125.0 |
| 36 | TXG | 10x Genomics, Inc. | Healthcare | 0.58% | $62.2M | $9.10B | — |
| 37 | ARWR | Arrowhead Pharmaceuticals, Inc. | Healthcare | 0.53% | $56.4M | $7.90B | — |
| 38 | SYRE | Spyre Therapeutics, Inc. | Healthcare | 0.51% | $55.1M | $7.47B | — |
| 39 | ALKS | Alkermes plc | Healthcare | 0.50% | $54.1M | $6.92B | 108.5 |
| 40 | TEM | Tempus AI, Inc. | Healthcare | 0.50% | $53.1M | $11.68B | — |
| 41 | AXSM | Axsome Therapeutics, Inc. | Healthcare | 0.49% | $52.8M | $8.23B | — |
| 42 | IONS | Ionis Pharmaceuticals, Inc. | Healthcare | 0.49% | $52.4M | $7.14B | — |
| 43 | PRAX | Praxis Precision Medicines, Inc. | Healthcare | 0.48% | $52.0M | $6.75B | — |
| 44 | ABVX | Abivax SA American Depositary Shares | Healthcare | 0.47% | $50.5M | $7.69B | — |
| 45 | BRKR | Bruker Corporation | Healthcare | 0.45% | $48.3M | $8.35B | — |
| 46 | RYTM | Rhythm Pharmaceuticals, Inc. | Healthcare | 0.41% | $43.7M | $5.91B | — |
| 47 | GRAL | GRAIL, Inc. | Healthcare | 0.40% | $42.4M | $5.26B | — |
| 48 | IOVA | Iovance Biotherapeutics, Inc. | Healthcare | 0.38% | $41.2M | $6.17B | — |
| 49 | PTCT | PTC Therapeutics, Inc. | Healthcare | 0.36% | $38.8M | $4.94B | — |
| 50 | COGT | Cogent Biosciences, Inc. | Healthcare | 0.36% | $38.4M | $5.12B | — |
| 51 | KOD | Kodiak Sciences Inc. | Healthcare | 0.34% | $36.3M | $5.39B | — |
| 52 | TVTX | Travere Therapeutics, Inc. | Healthcare | 0.34% | $36.3M | $4.61B | — |
| 53 | MIRM | Mirum Pharmaceuticals, Inc. | Healthcare | 0.33% | $34.9M | $5.20B | — |
| 54 | ORKA | Oruka Therapeutics, Inc. | Healthcare | 0.33% | $34.9M | $4.76B | — |
| 55 | DFTX | Definium Therapeutics, Inc. | Healthcare | 0.32% | $33.9M | $4.31B | — |
| 56 | CRSP | CRISPR Therapeutics AG | Healthcare | 0.30% | $32.5M | $4.76B | — |
| 57 | SRRK | Scholar Rock Holding Corporation | Healthcare | 0.30% | $32.2M | $4.86B | — |
| 58 | CAI | Caris Life Sciences, Inc. | Healthcare | 0.28% | $30.0M | $8.64B | 18.1 |
| 59 | TNGX | Tango Therapeutics, Inc. | Healthcare | 0.27% | $28.5M | $3.72B | — |
| 60 | VCYT | Veracyte, Inc. | Healthcare | 0.26% | $27.6M | $3.47B | 30.8 |
| 61 | CGON | CG Oncology, Inc. | Healthcare | 0.26% | $27.5M | $5.31B | — |
| 62 | ADPT | Adaptive Biotechnologies Corporation | Healthcare | 0.26% | $27.5M | $3.83B | — |
| 63 | ARQT | Arcutis Biotherapeutics, Inc. | Healthcare | 0.25% | $26.9M | $3.62B | 131.0 |
| 64 | ACAD | ACADIA Pharmaceuticals Inc. | Healthcare | 0.25% | $26.4M | $3.29B | 8.6 |
| 65 | XENE | Xenon Pharmaceuticals Inc. | Healthcare | 0.24% | $25.7M | $3.24B | — |
| 66 | ERAS | Erasca, Inc. | Healthcare | 0.23% | $25.0M | $4.68B | — |
| 67 | RLAY | Relay Therapeutics, Inc. | Healthcare | 0.23% | $24.4M | $3.57B | — |
| 68 | IDYA | IDEAYA Biosciences, Inc. | Healthcare | 0.22% | $23.9M | $3.17B | — |
| 69 | CDNA | CareDx, Inc | Healthcare | 0.22% | $23.9M | $3.31B | 30.8 |
| 70 | IBRX | ImmunityBio, Inc. | Healthcare | 0.22% | $23.7M | $9.73B | — |
| 71 | EWTX | Edgewise Therapeutics, Inc. | Healthcare | 0.22% | $23.7M | $4.04B | — |
| 72 | AMLX | Amylyx Pharmaceuticals, Inc. | Healthcare | 0.22% | $23.2M | $3.31B | — |
| 73 | LEGN | Legend Biotech Corporation | Healthcare | 0.21% | $22.8M | $3.59B | — |
| 74 | TARS | Tarsus Pharmaceuticals, Inc. | Healthcare | 0.21% | $22.5M | $3.19B | — |
| 75 | ABCL | AbCellera Biologics Inc. | Healthcare | 0.20% | $21.7M | $3.82B | — |
| 76 | DNLI | Denali Therapeutics Inc. | Healthcare | 0.20% | $21.3M | $2.81B | — |
| 77 | ELVN | Enliven Therapeutics, Inc. | Healthcare | 0.18% | $19.3M | $2.73B | — |
| 78 | DYN | Dyne Therapeutics, Inc. | Healthcare | 0.18% | $19.0M | $2.66B | — |
| 79 | IMVT | Immunovant, Inc. | Healthcare | 0.17% | $18.7M | $5.52B | — |
| 80 | SMMT | Summit Therapeutics Inc. | Healthcare | 0.17% | $18.4M | $11.67B | — |
| 81 | NRIX | Nurix Therapeutics, Inc. | Healthcare | 0.17% | $18.3M | $2.67B | 10.0 |
| 82 | BEAM | Beam Therapeutics Inc. | Healthcare | 0.16% | $17.7M | $2.42B | — |
| 83 | FTRE | Fortrea Holdings Inc. | Healthcare | 0.16% | $17.6M | $2.14B | — |
| 84 | ADMA | ADMA Biologics, Inc. | Healthcare | 0.16% | $16.9M | $2.39B | 15.3 |
| 85 | IRON | Disc Medicine, Inc. | Healthcare | 0.15% | $16.6M | $2.18B | — |
| 86 | AGIO | Agios Pharmaceuticals, Inc. | Healthcare | 0.15% | $16.6M | $1.87B | — |
| 87 | VCEL | Vericel Corporation | Healthcare | 0.15% | $16.4M | $2.05B | 85.4 |
| 88 | ZLAB | Zai Lab Limited | Healthcare | 0.14% | $15.1M | $2.60B | — |
| 89 | AUPH | Aurinia Pharmaceuticals Inc. | Healthcare | 0.14% | $14.7M | $2.20B | 7.2 |
| 90 | ZYME | Zymeworks Inc. | Healthcare | 0.14% | $14.5M | $1.80B | — |
| 91 | BHVN | Biohaven Ltd. | Healthcare | 0.13% | $14.4M | $1.63B | — |
| 92 | SRPT | Sarepta Therapeutics, Inc. | Healthcare | 0.13% | $14.4M | $1.81B | — |
| 93 | XNCR | Xencor, Inc. | Healthcare | 0.13% | $13.6M | $1.70B | — |
| 94 | RXRX | Recursion Pharmaceuticals, Inc. | Healthcare | 0.12% | $13.0M | $1.86B | — |
| 95 | BCRX | BioCryst Pharmaceuticals, Inc. | Healthcare | 0.12% | $13.0M | $1.99B | — |
| 96 | VERA | Vera Therapeutics, Inc. | Healthcare | 0.12% | $12.8M | $2.01B | — |
| 97 | GRFS | Grifols, S.A. | Healthcare | 0.12% | $12.7M | $5.20B | 9.9 |
| 98 | RCUS | Arcus Biosciences, Inc. | Healthcare | 0.12% | $12.6M | $2.82B | — |
| 99 | NVCR | NovoCure Limited | Healthcare | 0.11% | $12.1M | $1.64B | — |
| 100 | NAMS | NewAmsterdam Pharma Company N.V. | Healthcare | 0.11% | $12.0M | $2.37B | — |
| 101 | NVAX | Novavax, Inc. | Healthcare | 0.11% | $11.9M | $1.86B | — |
| 102 | MBX | MBX Biosciences, Inc. | Healthcare | 0.11% | $11.6M | $2.39B | — |
| 103 | RARE | Ultragenyx Pharmaceutical Inc. | Healthcare | 0.11% | $11.3M | $1.43B | — |
| 104 | QURE | uniQure N.V. | Healthcare | 0.10% | $11.3M | $1.51B | — |
| 105 | URGN | UroGen Pharma Ltd. | Healthcare | 0.10% | $11.1M | $1.69B | — |
| 106 | IMCR | Immunocore Holdings plc | Healthcare | 0.10% | $11.1M | $1.51B | — |
| 107 | NTLA | Intellia Therapeutics, Inc. | Healthcare | 0.10% | $11.0M | $1.60B | — |
| 108 | VIR | Vir Biotechnology, Inc. | Healthcare | 0.10% | $10.6M | $1.69B | — |
| 109 | CMPS | COMPASS Pathways plc | Healthcare | 0.10% | $10.2M | $1.49B | — |
| 110 | ABSI | Absci Corporation | Healthcare | 0.09% | $10.1M | $1.42B | — |
| 111 | STOK | Stoke Therapeutics, Inc. | Healthcare | 0.09% | $10.0M | $1.56B | — |
| 112 | LKFT | Lakefront Biotherapeutics NV | Healthcare | 0.09% | $9.9M | $1.96B | 2.8 |
| 113 | MLYS | Mineralys Therapeutics, Inc. | Healthcare | 0.09% | $9.8M | $1.79B | — |
| 114 | GPCR | Structure Therapeutics Inc. | Healthcare | 0.09% | $9.8M | $1.50B | — |
| 115 | ANAB | AnaptysBio, Inc. | Healthcare | 0.09% | $9.6M | $1.39B | — |
| 116 | SEPN | Septerna, Inc. | Healthcare | 0.09% | $9.4M | $1.70B | — |
| 117 | TRVI | Trevi Therapeutics, Inc. | Healthcare | 0.09% | $9.3M | $1.69B | — |
| 118 | NUVB | Nuvation Bio Inc. | Healthcare | 0.08% | $8.9M | $1.56B | — |
| 119 | SNDX | Syndax Pharmaceuticals, Inc. | Healthcare | 0.08% | $8.7M | $1.15B | — |
| 120 | TYRA | Tyra Biosciences, Inc. | Healthcare | 0.08% | $8.6M | $1.27B | — |
| 121 | PSNL | Personalis, Inc. | Healthcare | 0.08% | $8.5M | $1.67B | — |
| 122 | MAZE | Maze Therapeutics, Inc. | Healthcare | 0.08% | $8.2M | $1.53B | — |
| 123 | INBX | Inhibrx, Inc. | Healthcare | 0.08% | $8.1M | $1.32B | — |
| 124 | REPL | Replimune Group, Inc. | Healthcare | 0.08% | $8.1M | $1.02B | — |
| 125 | PGEN | Precigen, Inc. | Healthcare | 0.08% | $8.1M | $2.28B | — |
| 126 | TSHA | Taysha Gene Therapies, Inc. | Healthcare | 0.07% | $8.0M | $1.18B | — |
| 127 | PHVS | Pharvaris N.V. | Healthcare | 0.07% | $7.6M | $1.95B | — |
| 128 | CSTL | Castle Biosciences, Inc. | Healthcare | 0.07% | $7.6M | $976.4M | — |
| 129 | JANX | Janux Therapeutics, Inc. | Healthcare | 0.07% | $7.5M | $1.01B | — |
| 130 | GHRS | GH Research PLC | Healthcare | 0.07% | $7.4M | $1.25B | — |
| 131 | ORIC | ORIC Pharmaceuticals, Inc. | Healthcare | 0.07% | $7.2M | $1.28B | — |
| 132 | MNKD | MannKind Corporation | Healthcare | 0.07% | $7.2M | $977.5M | — |
| 133 | MESO | Mesoblast Limited | Healthcare | 0.07% | $7.2M | $1.72B | — |
| 134 | STVN | Stevanato Group S.p.A. | Healthcare | 0.07% | $7.0M | $5.16B | 33.2 |
| 135 | ZBIO | Zenas BioPharma, Inc. | Healthcare | 0.06% | $7.0M | $1.62B | — |
| 136 | RIGL | Rigel Pharmaceuticals, Inc. | Healthcare | 0.06% | $6.7M | $858.7M | 2.7 |
| 137 | KURA | Kura Oncology, Inc. | Healthcare | 0.06% | $6.4M | $807.8M | — |
| 138 | ANRO | Alto Neuroscience, Inc. | Healthcare | 0.06% | $6.1M | $861.0M | — |
| 139 | MRVI | Maravai LifeSciences Holdings, Inc. | Healthcare | 0.06% | $6.1M | $2.51B | — |
| 140 | ALVO | Alvotech | Healthcare | 0.06% | $6.0M | $1.78B | — |
| 141 | BCAX | Bicara Therapeutics Inc. | Healthcare | 0.06% | $6.0M | $1.11B | — |
| 142 | RAPP | Rapport Therapeutics, Inc. | Healthcare | 0.06% | $6.0M | $1.32B | — |
| 143 | MGTX | MeiraGTx Holdings plc | Healthcare | 0.05% | $5.6M | $891.3M | 10.7 |
| 144 | SLN | Silence Therapeutics plc | Healthcare | 0.05% | $5.3M | $539.5M | — |
| 145 | GERN | Geron Corporation | Healthcare | 0.05% | $5.2M | $751.7M | — |
| 146 | CGEM | Cullinan Oncology, Inc. | Healthcare | 0.05% | $5.1M | $794.7M | — |
| 147 | CRVS | Corvus Pharmaceuticals, Inc. | Healthcare | 0.05% | $5.0M | $800.8M | — |
| 148 | ABUS | Arbutus Biopharma Corporation | Healthcare | 0.05% | $4.9M | $646.8M | 5.3 |
| 149 | CTKB | Cytek Biosciences, Inc. | Healthcare | 0.05% | $4.9M | $682.4M | — |
| 150 | ANNX | Annexon, Inc. | Healthcare | 0.05% | $4.9M | $646.5M | — |
| 151 | AVBP | ArriVent BioPharma, Inc. | Healthcare | 0.04% | $4.8M | $821.5M | — |
| 152 | GLUE | Monte Rosa Therapeutics, Inc. | Healthcare | 0.04% | $4.8M | $831.0M | — |
| 153 | ALMS | Alumis Inc. | Healthcare | 0.04% | $4.8M | $792.1M | — |
| 154 | IRWD | Ironwood Pharmaceuticals, Inc. | Healthcare | 0.04% | $4.6M | $578.3M | 4.5 |
| 155 | ZVRA | Zevra Therapeutics, Inc. | Healthcare | 0.04% | $4.5M | $590.3M | 10.8 |
| 156 | PACB | Pacific Biosciences of California, Inc. | Healthcare | 0.04% | $4.5M | $537.7M | — |
| 157 | FDMT | 4D Molecular Therapeutics, Inc. | Healthcare | 0.04% | $4.4M | $670.7M | — |
| 158 | OPK | OPKO Health, Inc. | Healthcare | 0.04% | $4.4M | $1.14B | — |
| 159 | OABI | OmniAb, Inc. | Healthcare | 0.04% | $4.4M | $667.3M | — |
| 160 | SGMT | Sagimet Biosciences Inc. | Healthcare | 0.04% | $4.3M | $568.7M | — |
| 161 | WVE | Wave Life Sciences Ltd. | Healthcare | 0.04% | $4.2M | $616.8M | — |
| 162 | MYGN | Myriad Genetics, Inc. | Healthcare | 0.04% | $3.9M | $380.7M | — |
| 163 | CADL | Candel Therapeutics, Inc. | Healthcare | 0.04% | $3.9M | $626.7M | — |
| 164 | OLMA | Olema Pharmaceuticals, Inc. | Healthcare | 0.04% | $3.8M | $575.7M | — |
| 165 | SLDB | Solid Biosciences Inc. | Healthcare | 0.04% | $3.8M | $593.0M | — |
| 166 | DNA | Ginkgo Bioworks Holdings, Inc. | Healthcare | 0.03% | $3.7M | $691.6M | — |
| 167 | SVRA | Savara Inc. | Healthcare | 0.03% | $3.6M | $914.3M | — |
| 168 | CTMX | CytomX Therapeutics, Inc. | Healthcare | 0.03% | $3.5M | $496.8M | — |
| 169 | ARVN | Arvinas, Inc. | Healthcare | 0.03% | $3.4M | $449.7M | 26.8 |
| 170 | RGNX | REGENXBIO Inc. | Healthcare | 0.03% | $3.2M | $457.1M | — |
| 171 | SANA | Sana Biotechnology, Inc. | Healthcare | 0.03% | $3.2M | $679.5M | — |
| 172 | ACRS | Aclaris Therapeutics, Inc. | Healthcare | 0.03% | $3.1M | $482.8M | — |
| 173 | AURA | Aura Biosciences, Inc. | Healthcare | 0.03% | $3.1M | $632.6M | — |
| 174 | ALT | Altimmune, Inc. | Healthcare | 0.03% | $3.0M | $427.9M | — |
| 175 | NGNE | Neurogene Inc. | Healthcare | 0.03% | $2.9M | $465.3M | — |
| 176 | DSGN | Design Therapeutics, Inc. | Healthcare | 0.03% | $2.7M | $645.2M | — |
| 177 | PRTA | Prothena Corporation plc | Healthcare | 0.02% | $2.7M | $428.7M | — |
| 178 | PHAT | Phathom Pharmaceuticals, Inc. | Healthcare | 0.02% | $2.7M | $559.8M | — |
| 179 | CCCC | C4 Therapeutics, Inc. | Healthcare | 0.02% | $2.7M | $340.2M | — |
| 180 | PRME | Prime Medicine, Inc. | Healthcare | 0.02% | $2.6M | $629.4M | — |
| 181 | FLGT | Fulgent Genetics, Inc. | Healthcare | 0.02% | $2.6M | $545.1M | — |
| 182 | EDIT | Editas Medicine, Inc. | Healthcare | 0.02% | $2.6M | $360.9M | — |
| 183 | ENTA | Enanta Pharmaceuticals, Inc. | Healthcare | 0.02% | $2.3M | $323.3M | — |
| 184 | ARCT | Arcturus Therapeutics Holdings Inc. | Healthcare | 0.02% | $2.3M | $293.9M | — |
| 185 | EBS | Emergent BioSolutions Inc. | Healthcare | 0.02% | $2.2M | $327.1M | — |
| 186 | ALLO | Allogene Therapeutics, Inc. | Healthcare | 0.02% | $2.2M | $452.6M | — |
| 187 | FULC | Fulcrum Therapeutics, Inc. | Healthcare | 0.02% | $2.1M | $278.8M | — |
| 188 | AUTL | Autolus Therapeutics plc | Healthcare | 0.02% | $2.1M | $425.9M | — |
| 189 | SPRY | ARS Pharmaceuticals, Inc. | Healthcare | 0.02% | $2.1M | $399.8M | — |
| 190 | AVIR | Atea Pharmaceuticals, Inc. | Healthcare | 0.02% | $1.9M | $346.5M | — |
| 191 | CTNM | Contineum Therapeutics, Inc. | Healthcare | 0.02% | $1.8M | $266.4M | — |
| 192 | LAB | Standard BioTools Inc. | Healthcare | 0.02% | $1.8M | $246.9M | — |
| 193 | RCKT | Rocket Pharmaceuticals, Inc. | Healthcare | 0.02% | $1.8M | $239.3M | — |
| 194 | VNDA | Vanda Pharmaceuticals Inc. | Healthcare | 0.02% | $1.7M | $243.7M | — |
| 195 | CABA | Cabaletta Bio, Inc. | Healthcare | 0.02% | $1.7M | $239.1M | — |
| 196 | IMRX | Immuneering Corporation | Healthcare | 0.02% | $1.7M | $232.3M | — |
| 197 | KYTX | Kyverna Therapeutics, Inc. | Healthcare | 0.01% | $1.6M | $350.7M | — |
| 198 | KROS | Keros Therapeutics, Inc. | Healthcare | 0.01% | $1.6M | $211.4M | — |
| 199 | CATX | Perspective Therapeutics, Inc. | Healthcare | 0.01% | $1.5M | $247.7M | — |
| 200 | LXEO | Lexeo Therapeutics, Inc. | Healthcare | 0.01% | $1.5M | $216.7M | — |
| 201 | TECX | Tectonic Therapeutic Inc. | Healthcare | 0.01% | $1.5M | $403.7M | — |
| 202 | QSI | Quantum-Si incorporated | Healthcare | 0.01% | $1.5M | $245.1M | — |
| 203 | LCTX | Lineage Cell Therapeutics, Inc. | Healthcare | 0.01% | $1.4M | $247.4M | — |
| 204 | BIOA | BioAge Labs, Inc | Healthcare | 0.01% | $1.3M | $222.1M | — |
| 205 | PEPG | PepGen Inc. | Healthcare | 0.01% | $1.3M | $179.8M | — |
| 206 | ACIU | AC Immune SA | Healthcare | 0.01% | $1.1M | $237.6M | — |
| 207 | ADCT | ADC Therapeutics SA | Healthcare | 0.01% | $1.1M | $178.7M | — |
| 208 | BBOT | BridgeBio Oncology Therapeutics, Inc. | Healthcare | 0.01% | $997,779.02 | $226.1M | — |
| 209 | BCYC | Bicycle Therapeutics plc | Healthcare | 0.01% | $997,779.02 | $241.5M | — |
| 210 | CDXS | Codexis, Inc. | Healthcare | 0.01% | $976,321.41 | $135.8M | — |
| 211 | AVXL | Anavex Life Sciences Corp. | Healthcare | 0.01% | $879,762.15 | $121.4M | — |
| 212 | PYXS | Pyxis Oncology, Inc. | Healthcare | 0.01% | $847,575.73 | $200.7M | — |
| 213 | LRMR | Larimar Therapeutics, Inc. | Healthcare | 0.01% | $826,118.11 | $206.2M | — |
| 214 | TRDA | Entrada Therapeutics, Inc. | Healthcare | 0.01% | $815,389.31 | $170.2M | — |
| 215 | QTRX | Quanterix Corporation | Healthcare | 0.01% | $815,389.31 | $135.7M | — |
| 216 | NBP | NovaBridge Biosciences | Healthcare | 0.01% | $804,660.50 | $146.2M | — |
| 217 | UPB | Upstream Bio, Inc. | Healthcare | 0.01% | $783,202.89 | $151.2M | — |
| 218 | BDTX | Black Diamond Therapeutics, Inc. | Healthcare | 0.01% | $772,474.08 | $98.8M | — |
| 219 | HUMA | Humacyte, Inc. | Healthcare | 0.01% | $772,474.08 | $119.2M | — |
| 220 | SION | Sionna Therapeutics, Inc. | Healthcare | 0.01% | $761,745.27 | $175.6M | — |
| 221 | VYGR | Voyager Therapeutics, Inc. | Healthcare | 0.01% | $708,101.24 | $117.1M | — |
| 222 | LENZ | LENZ Therapeutics, Inc. | Healthcare | 0.01% | $686,643.63 | $102.7M | — |
| 223 | TNYA | Tenaya Therapeutics, Inc. | Healthcare | 0.01% | $632,999.59 | $85.4M | — |
| 224 | LYEL | Lyell Immunopharma, Inc. | Healthcare | 0.01% | $557,897.95 | $199.0M | — |
| 225 | TKNO | Alpha Teknova, Inc. | Healthcare | 0.00% | $504,253.91 | $380.1M | — |
| 226 | FHTX | Foghorn Therapeutics Inc. | Healthcare | 0.00% | $472,067.49 | $109.9M | — |
| 227 | GOSS | Gossamer Bio, Inc. | Healthcare | 0.00% | $396,965.85 | $53.6M | — |
| 228 | MENS | Jyong Biotech Ltd. | Healthcare | 0.00% | $375,508.23 | $139.9M | — |
| 229 | AARD | Aardvark Therapeutics, Inc. | Healthcare | 0.00% | $354,050.62 | $82.7M | — |
| 230 | CRBU | Caribou Biosciences, Inc. | Healthcare | 0.00% | $354,050.62 | $50.4M | — |
| 231 | AKE | AKERO THERAPEUTICS CVR | Other | 0.00% | $321,864.20 | — | — |
| 232 | CLLS | Cellectis S.A. | Healthcare | 0.00% | $225,304.94 | $104.8M | — |
| 233 | NMRA | Neumora Therapeutics, Inc. | Healthcare | 0.00% | $214,576.13 | $89.0M | — |
| 234 | IMMP | Immutep Limited | Healthcare | 0.00% | $118,016.87 | $23.6M | — |
Weights as a percentage of net assets. Value held = weight × net assets ($10.73B). Market cap and P/E from each company's latest fundamentals (U.S.-listed stocks).
IBB sector breakdown
Sum of the weights of the holdings in each sector.
IBB top industries
Biotechnology
63.7%
Drug Manufacturers - General
19.4%
Diagnostics & Research
10.4%
Drug Manufacturers - Specialty & Generic
3.7%
Medical Devices
1.3%
Medical Instruments & Supplies
0.7%
Health Information Services
0.5%
Medical Care Facilities
0.1%
IBB overlap with other ETFs
| ETF | Fund | Overlap | Shared holdings | Expense ratio |
|---|---|---|---|---|
| IBBQ | Invesco Nasdaq Biotechnology ETF | 83.5% | 196 of 245 | 0.18% |
| BBH | VanEck Biotech ETF | 65.1% | 21 of 25 | 0.33% |
| BIB | ProShares Ultra Nasdaq Biotechnology | 53.8% | 196 of 245 | 0.95% |
| BIS | ProShares UltraShort Nasdaq Biotechnology | 48.6% | 47 of 104 | 0.96% |
| PBE | Invesco Dynamic Biotechnology & Genome ETF | 43.2% | 25 of 31 | 0.56% |
| IWM | iShares Russell 2000 ETF | 9.9% | 165 of 1,962 | 0.19% |
Overlap = sum over shared holdings of the smaller of the two weights. 100% means identical portfolios.
About the IBB portfolio
iShares Biotechnology ETF holds 236 positions. The ten largest make up 51.0% of the fund and the top 50 84.3%, so it behaves like a portfolio of about 28 equally weighted stocks. The biggest positions are Amgen Inc. (8.46%), Gilead Sciences, Inc. (8.27%), Vertex Pharmaceuticals Incorporated (7.82%), Regeneron Pharmaceuticals, Inc. (5.97%), Moderna, Inc. (5.12%).
By sector, Healthcare is 99.8%, Other is 0.0%. Holdings data is from the fund's latest portfolio as reported by EODHD on October 25, 2026; positions change as the fund rebalances.
Related: IBB chart, IBB performance, IBB dividends, IBB overview.
IBB holdings FAQ
How many holdings does IBB have?
IBB holds 236 positions as of October 25, 2026.
What are the top 10 holdings of IBB?
The ten largest holdings are Amgen Inc. (8.46%), Gilead Sciences, Inc. (8.27%), Vertex Pharmaceuticals Incorporated (7.82%), Regeneron Pharmaceuticals, Inc. (5.97%), Moderna, Inc. (5.12%), Natera, Inc. (3.96%), argenx SE (3.32%), Illumina, Inc. (2.96%), Biogen Inc. (2.54%), Revolution Medicines, Inc. (2.54%). Together they are 51.0% of the fund.
What percentage of IBB is Amgen Inc.?
Amgen Inc. is the largest holding at 8.46% of net assets, about $907.5M of the fund's $10.73B.
How concentrated is IBB?
The top 10 holdings are 51.0% of the fund. By the effective number of holdings (1 divided by the sum of squared weights) IBB behaves like a portfolio of about 28 equally weighted stocks.