BioCryst Pharmaceuticals, Inc. (BCRX) Ownership

NASDAQ: BCRXTop holders, insider trades and short interest.

BCRX ownership summary

as of October 18, 2026
Institutions
105.4%
of shares outstanding
Insiders
1.28%
of shares outstanding
Shares outstanding
255.5M
Float
222.3M
shares available to trade
Short interest
10.84%
27.5M shares short
Days to cover
5.15
short interest down 21.1% vs prior month
  • Institutions 105.38%
  • Insiders 1.28%

BCRX top institutional holders

20 largest
BioCryst Pharmaceuticals, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1BlackRock Inc9.35%23.9M$186.1M+1.2M (+5.5%)June 30, 2026
2RA Capital Management, LLC6.19%15.8M$123.3M—June 30, 2026
3State Street Corp5.94%15.2M$118.3M+3.0M (+24.4%)June 30, 2026
4Deerfield Management Co5.91%15.1M$117.6M+58,403 (+0.4%)June 30, 2026
5Vanguard Capital Management, LLC4.45%11.4M$88.5M+228,474 (+2.1%)June 30, 2026
6Vanguard Portfolio Management, LLC4.36%11.1M$86.8M−105,467 (−0.9%)June 30, 2026
7TCG Crossover Management, LLC4.31%11.0M$85.9M—June 30, 2026
8Perceptive Advisors LLC4.03%10.3M$80.3M+2.9M (+38.7%)June 30, 2026
9Jupiter Topco LLC3.73%9.5M$74.3M+9.5M (0.0%)June 30, 2026
10HHG PLC3.49%8.9M$69.4M+1.5M (+20.3%)March 31, 2026
11Vestal Point Capital LP3.25%8.3M$64.7M+1.3M (+18.1%)June 30, 2026
12Two Sigma Investments LLC2.65%6.8M$52.8M+382,721 (+6.0%)June 30, 2026
13Geode Capital Management, LLC2.45%6.2M$48.7M+465,270 (+8.0%)June 30, 2026
14Aberdeen Group PLC2.08%5.3M$41.4M+270,201 (+5.4%)June 30, 2026
15UBS Group AG1.99%5.1M$39.6M+134,286 (+2.7%)June 30, 2026
16Bank of America Corp1.88%4.8M$37.4M−290,481 (−5.7%)June 30, 2026
17The Goldman Sachs Group Inc1.75%4.5M$34.9M+2.1M (+90.9%)June 30, 2026
18Frazier Life Sciences Management, L.P.1.57%4.0M$31.2M—June 30, 2026
19Nuveen, LLC1.57%4.0M$31.2M+187,974 (+4.9%)June 30, 2026
20Nantahala Capital Management, LLC1.49%3.8M$29.6M+1.8M (+91.3%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 15 holders added 25.1M shares and 2 cut 396K.

BCRX top mutual fund and ETF holders

20 largest
BioCryst Pharmaceuticals, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest3.17%8.1M$63.0M−16,022 (−0.2%)August 31, 2026
2State Street® SPDR® S&P® Biotech ETF2.71%6.9M$54.0M−132,550 (−1.9%)September 30, 2026
3iShares Russell 2000 ETF2.27%5.8M$45.1M−66,752 (−1.1%)September 30, 2026
4Vanguard Small Cap Index1.13%2.9M$22.4M−44,119 (−1.5%)September 30, 2026
5abrdn Healthcare Investors1.03%2.6M$20.4M—September 30, 2026
6Fidelity Small Cap Index0.99%2.5M$19.8M+22,167 (+0.9%)July 31, 2026
7abrdn Healthcare Opportunities0.91%2.3M$18.1M+115,591 (+5.2%)August 31, 2026
8Candriam Eqs L Biotech C USD Cap0.89%2.3M$17.8M+2.0M (+628.2%)March 31, 2026
9iShares Russell 2000 Growth ETF0.82%2.1M$16.4M−2,657 (−0.1%)September 30, 2026
10Janus Henderson Hrzn Biotec E2 USD0.82%2.1M$16.3M+233,739 (+12.6%)June 30, 2026
11Vanguard Strategic Equity Inv0.81%2.1M$16.1M−194,179 (−8.6%)June 30, 2026
12iShares Biotechnology ETF0.67%1.7M$13.3M−12,960 (−0.8%)September 30, 2026
13Vanguard MStar Small Cap Growth Indx Inv0.63%1.6M$12.5M−72,707 (−4.3%)September 30, 2026
14abrdn Life Sciences Investors0.54%1.4M$10.7M+165,636 (+13.7%)September 30, 2026
15CREF Total Global Stock Account R30.53%1.3M$10.5M−79,321 (−5.6%)August 31, 2026
16Vanguard Explorer Inv0.52%1.3M$10.4M—June 30, 2026
17Vanguard Russell 2000 ETF0.51%1.3M$10.2M−35,264 (−2.6%)September 30, 2026
18Schwab US Small-Cap ETF™0.49%1.3M$9.7M+846 (+0.1%)September 30, 2026
19Fidelity Extended Market Index0.48%1.2M$9.5M−10,800 (−0.9%)August 31, 2026
20Invesco Biotechnology & Genome ETF0.47%1.2M$9.3M—September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

BCRX insider transactions

latest 7
BioCryst Pharmaceuticals, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-03-16Alane P BarnesSell$9.15150,000$1.4M
2025-12-22Alane P BarnesSell$7.6521,773$166,563
2025-12-03Alane P BarnesSell$7.6519,770$151,240
2025-12-02Alane P BarnesSell$7.2150,906$367,032
2025-12-01Alane P BarnesSell$7.1091,004$646,128
2025-11-13Gilbert Ray Cisneros, Jr.Buy$6.90——
2025-08-13Theresa HeggieSell$8.5170,000$595,700

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

BCRX shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns BCRX

Institutional investors own 105.4% of BioCryst Pharmaceuticals's shares and insiders 1.28%. The largest holder is BlackRock Inc with 9.35% of the shares (23.9M), as of June 30, 2026. Among the top 20 institutions, 15 added shares and 2 reduced their stake in the latest filings. Short interest is 10.84% of the float, or 5.15 days of average trading volume. The share count rose 205.1% since 2014.

Related: BCRX analyst forecast, BCRX key metrics. See the BCRX stock overview for the latest quote and news.

BCRX ownership FAQ

Who owns the most BioCryst Pharmaceuticals stock?

The largest shareholders of BioCryst Pharmaceuticals are BlackRock Inc (9.35%), RA Capital Management, LLC (6.19%), State Street Corp (5.94%), Deerfield Management Co (5.91%), Vanguard Capital Management, LLC (4.45%).

What percentage of BioCryst Pharmaceuticals is owned by institutions?

Institutions hold 105.4% of BioCryst Pharmaceuticals's shares outstanding; insiders hold 1.28%.

Which funds own BioCryst Pharmaceuticals?

The largest fund holders of BioCryst Pharmaceuticals are Vanguard MStar Total Stk Mkt Idx Invest (3.17%), State Street® SPDR® S&P® Biotech ETF (2.71%), iShares Russell 2000 ETF (2.27%), Vanguard Small Cap Index (1.13%), abrdn Healthcare Investors (1.03%).

What is BioCryst Pharmaceuticals's short interest?

27.5M shares of BioCryst Pharmaceuticals were sold short, 10.84% of the float; at the average daily volume it would take 5.15 days to cover.

Are insiders buying or selling BioCryst Pharmaceuticals?

Of the latest 7 reported insider transactions in BioCryst Pharmaceuticals (since August 13, 2025), 1 were purchases and 6 were sales.

How many shares of BioCryst Pharmaceuticals are outstanding?

BioCryst Pharmaceuticals has 255.5M shares outstanding, of which 222.3M are in the public float.

Drug Manufacturers - Specialty & Generic: ownership