ProShares UltraShort Nasdaq Biotechnology (BIS) Performance

NASDAQ: BISTotal returns, calendar years, drawdowns and risk since 2010.

BIS total return

Distributions reinvested · as of Oct 23, 2026
YTD
−37.8%
since Dec 31, 2025
1 year
−49.2%
total return
5 years
−19.4%
a year
10 years
−26.6%
a year
Since first price
−32.9%
a year since 2010

BIS trailing returns vs SPY, QQQ, AGG

BIS trailing returns
PeriodBIS total returnPrice onlyS&P 500 (SPY)Nasdaq-100 (QQQ)U.S. bonds (AGG)
1 month−0.3%−0.3%−1.0%−5.0%+0.9%
3 months−15.3%−16.4%+3.2%+1.9%−0.4%
6 months−30.6%−32.1%+7.8%+8.4%−1.5%
YTD−37.8%−39.6%+12.3%+15.1%−1.0%
1 year−49.2%−51.1%+14.4%+15.9%−1.1%
3 years−74.2%−36.4%/yr−77.0%+87.4%+23.3%/yr+101.4%+26.3%/yr+16.6%+5.2%/yr
5 years−66.0%−19.4%/yr−69.9%+79.3%+12.4%/yr+94.0%+14.2%/yr−0.8%−0.2%/yr
10 years−95.5%−26.6%/yr−96.1%+315.9%+15.3%/yr+538.9%+20.4%/yr+14.0%+1.3%/yr
15 years−99.8%−33.8%/yr−99.8%+696.0%+14.8%/yr+1,299.3%+19.2%/yr+32.2%+1.9%/yr
Since inceptionApr 8, 2010−99.9%−32.9%/yr−99.9%———

Total return from adjusted closes (distributions reinvested, before tax). Periods of 3 years or more are also shown annualized. Price only excludes distributions.

Growth of $10,000: BIS vs SPY

BISS&P 500 (SPY)

From Apr 8, 2010: BIS grew to $14, SPY to $85,597.

Year-end values with distributions reinvested, no taxes or trading costs. Start: first common trading day of both funds.

BIS returns by calendar year

BISSPY

3 of 15 full years positive. Best 2016 (+21.9%), worst 2013 (−68.9%). 2026 is year to date.

BIS annual returns table

BIS calendar-year returns
YearBISLargest dropSPYQQQAGG
2026YTD−37.8%−45.8%+12.3%+15.1%−1.0%
2025−46.0%−61.1%+17.7%+20.8%+7.2%
2024+4.8%−31.2%+24.9%+25.6%+1.3%
2023−6.5%−32.2%+26.2%+54.9%+5.7%
2022−2.1%−48.5%−18.2%−32.6%−13.0%
2021−14.7%−34.1%+28.7%+27.4%−1.8%
2020−56.0%−71.8%+18.3%+48.6%+7.5%
2019−41.0%−42.8%+31.2%+39.0%+8.5%
2018+5.1%−33.4%−4.6%−0.1%+0.1%
2017−37.0%−41.4%+21.7%+32.7%+3.6%
2016+21.9%−44.8%+12.0%+7.1%+2.4%
2015−37.6%−47.8%+1.2%+9.4%+0.5%
2014−55.4%−59.7%+13.5%+19.2%+6.0%
2013−68.9%−66.8%+32.3%+36.6%−2.0%
2012−49.1%−54.7%+16.0%+18.1%+3.8%
2011−35.8%−42.2%+1.9%+3.4%+7.7%

Largest drop = deepest fall from a high within that calendar year.

Calendar-year return vs largest drop within the year

Calendar-year returnLargest drop within the year

Most years include a sizable fall at some point even when the year ends higher.

BIS largest drawdowns

Now 99.9% below the high
BIS largest drawdowns
PeakDeclineBottomRecoveredFallUnderwater
Jul 6, 2010−99.9%Aug 19, 2026not yet16.1 years16.3 years so far
Jun 9, 2010−13.0%Jun 15, 2010Jul 1, 20106 days22 days
May 6, 2010−11.8%May 12, 2010May 20, 20106 days14 days

Declines from a closing high (distributions reinvested) of 10% or more. Underwater = time from the peak until the old high was regained.

BIS risk statistics

BIS risk statistics
Statistic3 years5 years10 yearsSince 2010
Annualized return−34.6%−19.0%−25.8%−33.2%
Volatility (annualized)33.2%34.0%37.3%39.6%
Sharpe ratio-1.23-0.55-0.66-0.85
Sortino ratio-1.36-0.72-0.84-1.08
Best month+16.2%+25.6%+33.3%+53.7%
Worst month−21.7%−21.7%−27.8%−27.8%
Best 12 months+11.9%+40.1%+49.1%+49.1%
Worst 12 months−60.1%−60.1%−65.6%−73.8%
Positive months33%43%42%38%
Beta vs S&P 500-1.15-1.17-1.39—
Correlation with S&P 500-0.43-0.54-0.57—

From monthly total returns. Sharpe and Sortino use 1–3 month T-bills (BIL) as the risk-free rate, so they need history from 2007 on.

BIS rolling returns

BIS rolling returns
Holding periodPeriodsWorstMedianBestPositive
1-year187−73.8%−35.6%+49.1%19%
3-year (a year)163−59.6%−28.7%−1.0%0%
5-year (a year)139−55.2%−25.8%−9.7%0%
10-year (a year)79−41.1%−28.4%−16.0%0%

Every holding period starting at a month-end since 2010. Returns for 3 years and longer are annualized.

BIS performance overview

ProShares UltraShort Nasdaq Biotechnology (BIS) returned −49.2% over the past year and −26.6% a year over ten years, with distributions reinvested. Since its first recorded price in 2010 it has returned −32.9% a year, turning $10,000 into about $14. Over the same year S&P 500 (SPY) returned +14.4%.

The deepest decline was −99.9%, from Jul 6, 2010 to Aug 19, 2026; the fund has not yet regained that high. BIS finished 3 of its 15 full calendar years with a gain; the best year was 2016 (+21.9%) and the worst 2013 (−68.9%). Volatility has been 39.6% a year.

Related: BIS chart, BIS holdings, BIS dividends. See the BIS overview for the latest quote and fund facts.

BIS performance FAQ

What is the BIS return over the past year?

BIS returned −49.2% over the 12 months to October 23, 2026, including reinvested distributions. On price alone it fell 51.1%.

What is the average annual return of BIS?

BIS has returned −19.4% a year over 5 years, −26.6% a year over 10 years, −32.9% a year since April 8, 2010 (total return, distributions reinvested).

How much would $10,000 invested in BIS be worth?

$10,000 invested in BIS at its first recorded close on April 8, 2010 would be worth about $14 on October 23, 2026 with distributions reinvested.

What was the worst year for BIS?

The worst calendar year was 2013, with a total return of −68.9%. The best was 2016 at +21.9%.

What is the biggest drawdown of BIS?

The largest peak-to-trough decline was −99.9% between July 6, 2010 and August 19, 2026. It has not yet recovered to that high; it is 99.9% below its peak.

How volatile is BIS?

Over the past 3 years BIS had an annualized volatility of 33.2% and a Sharpe ratio of -1.23 (excess return over 1–3 month T-bills per unit of risk).