Fulcrum Therapeutics, Inc. (FULC) Ownership

NASDAQ: FULCTop holders, insider trades and short interest.

FULC ownership summary

as of October 18, 2026
Institutions
102.2%
of shares outstanding
Insiders
3.35%
of shares outstanding
Shares outstanding
76.4M
Float
63.5M
shares available to trade
Short interest
9.41%
7.1M shares short
Days to cover
4.90
short interest down 1.2% vs prior month
  • Institutions 102.19%
  • Insiders 3.35%

FULC top institutional holders

20 largest
Fulcrum Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Nantahala Capital Management, LLC14.34%11.0M$40.0M+7.9M (+259.0%)June 30, 2026
2BlackRock Inc11.55%8.8M$32.2M+3.4M (+63.7%)June 30, 2026
3EcoR1 Capital, LLC8.58%6.5M$23.9M+6.5M (0.0%)June 30, 2026
4TANG CAPITAL MANAGEMENT LLC8.54%6.5M$23.8M+6.5M (0.0%)June 30, 2026
5Suvretta Capital Management, LLC4.82%3.7M$13.4M−2.9M (−43.9%)June 30, 2026
6D. E. Shaw & Co LP3.99%3.0M$11.1M+1.4M (+87.5%)June 30, 2026
7Citadel Advisors Llc3.54%2.7M$9.9M+1.4M (+109.2%)June 30, 2026
8Vanguard Capital Management, LLC3.53%2.7M$9.8M+4,268 (+0.2%)June 30, 2026
9Jane Street Group LLC2.90%2.2M$8.1M+1.9M (+614.4%)June 30, 2026
10State Street Corp2.67%2.0M$7.4M+487,174 (+31.4%)June 30, 2026
11Adage Capital Partners Gp LLC2.62%2.0M$7.3M+1.6M (+400.0%)June 30, 2026
12GSK PLC2.34%1.8M$6.5M—June 30, 2026
13Qube Research & Technologies2.29%1.7M$6.4M+773,728 (+79.4%)June 30, 2026
14Assenagon Asset Management SA2.19%1.7M$6.1M+476,535 (+39.9%)June 30, 2026
15Renaissance Technologies Corp2.16%1.6M$6.0M+1.6M (+12,016.2%)June 30, 2026
16ADAR1 Capital Management LLC2.05%1.6M$5.7M+1.4M (+1,098.7%)June 30, 2026
17Millennium Management LLC1.95%1.5M$5.4M+1.1M (+316.8%)June 30, 2026
18Geode Capital Management, LLC1.88%1.4M$5.2M−54,409 (−3.7%)June 30, 2026
19Marshall Wace Asset Management Ltd1.78%1.4M$5.0M+1.4M (0.0%)June 30, 2026
20UBS Group AG1.64%1.3M$4.6M+938,724 (+297.8%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 17 holders added 39.0M shares and 2 cut 2.9M.

FULC top mutual fund and ETF holders

20 largest
Fulcrum Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest2.72%2.1M$7.6M—August 31, 2026
2iShares Russell 2000 ETF2.29%1.7M$6.4M−20,160 (−1.1%)September 30, 2026
3BlackRock Advantage Small Cap Core Instl2.00%1.5M$5.6M+101,537 (+7.1%)August 31, 2026
4Fidelity Small Cap Index0.85%646K$2.4M+1,946 (+0.3%)July 31, 2026
5iShares Russell 2000 Value ETF0.83%632K$2.3M+958 (+0.2%)September 30, 2026
6iShares Biotechnology ETF0.75%576K$2.1M−4,368 (−0.8%)September 30, 2026
7Fidelity Enhanced Small Cap Core ETF0.66%504K$1.8M+1,056 (+0.2%)September 30, 2026
8Vanguard Russell 2000 ETF0.52%396K$1.4M+55,983 (+16.5%)September 30, 2026
9Schwab US Small-Cap ETF™0.43%326K$1.2M+216 (+0.1%)September 30, 2026
10Strategic Advisers U.S. Total Stock0.38%293K$1.1M+75,292 (+34.6%)August 31, 2026
11Fidelity Extended Market Index0.36%275K$1.0M+109,506 (+66.0%)August 31, 2026
12Xtrackers S&P 500 2xLev Dly Swap ETF 1C0.33%250K$913,562—December 31, 2025
13iShares Micro-Cap ETF0.28%214K$781,388−1,476 (−0.7%)September 30, 2026
14BlackRock Advantage Small Cap Gr Instl0.25%194K$708,991+35,569 (+22.4%)August 31, 2026
15Vanguard Strategic Small-Cap Equity Inv0.25%191K$697,592+191,121 (0.0%)June 30, 2026
16BlackRock Advantage SMID Cap Instl0.25%189K$690,682+52,358 (+38.3%)August 31, 2026
17DFA US Micro Cap I0.23%176K$643,254+7,630 (+4.5%)August 31, 2026
18DFA US Small Cap I0.21%157K$573,411—August 31, 2026
19Simplify Health Care ETF0.20%153K$559,508—September 30, 2026
20Vanguard Health Care ETF0.19%142K$519,289+156 (+0.1%)September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

FULC insider transactions

latest 4
Fulcrum Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-01-02Robert J GouldSell$11.8715,000$178,050
2025-12-08Ra Capital Management, L.P.Sell$13.984,175,139$58.4M
2025-11-19Robert J GouldSell$11.0315,000$165,450
2025-05-08Greg TourangeauSell$5.06498$2,520

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

FULC shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns FULC

Institutional investors own 102.2% of Fulcrum Therapeutics's shares and insiders 3.35%. The largest holder is Nantahala Capital Management, LLC with 14.34% of the shares (11.0M), as of June 30, 2026. Among the top 20 institutions, 17 added shares and 2 reduced their stake in the latest filings. Short interest is 9.41% of the float, or 4.90 days of average trading volume. The share count rose 6,235.5% since 2017.

Related: FULC analyst forecast, FULC key metrics. See the FULC stock overview for the latest quote and news.

FULC ownership FAQ

Who owns the most Fulcrum Therapeutics stock?

The largest shareholders of Fulcrum Therapeutics are Nantahala Capital Management, LLC (14.34%), BlackRock Inc (11.55%), EcoR1 Capital, LLC (8.58%), TANG CAPITAL MANAGEMENT LLC (8.54%), Suvretta Capital Management, LLC (4.82%).

What percentage of Fulcrum Therapeutics is owned by institutions?

Institutions hold 102.2% of Fulcrum Therapeutics's shares outstanding; insiders hold 3.35%.

Which funds own Fulcrum Therapeutics?

The largest fund holders of Fulcrum Therapeutics are Vanguard MStar Total Stk Mkt Idx Invest (2.72%), iShares Russell 2000 ETF (2.29%), BlackRock Advantage Small Cap Core Instl (2.00%), Fidelity Small Cap Index (0.85%), iShares Russell 2000 Value ETF (0.83%).

What is Fulcrum Therapeutics's short interest?

7.1M shares of Fulcrum Therapeutics were sold short, 9.41% of the float; at the average daily volume it would take 4.90 days to cover.

Are insiders buying or selling Fulcrum Therapeutics?

Of the latest 4 reported insider transactions in Fulcrum Therapeutics (since May 8, 2025), 0 were purchases and 4 were sales.

How many shares of Fulcrum Therapeutics are outstanding?

Fulcrum Therapeutics has 76.4M shares outstanding, of which 63.5M are in the public float.

Biotechnology: ownership