Fulcrum Therapeutics, Inc. (FULC) Cash Flow Statement

NASDAQ: FULCOperating cash, capex, free cash flow and buybacks.

Where FULC’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$60.1M
Capital expenditures
$314,000
Free cash flow
−$60.4M
Returned to shareholders
—
Change in cash
$139.3M
cash at year-end $198.7M
Investments (net): $31.0MInvestments (net)$31.0MShares issued: $164.5MShares issued$164.5MOther financing: $4.2MOther financing$4.2MCash used in operations: $60.1MCash used in operations$60.1M · 30%Added to cash: $139.3MAdded to cash$139.3M · 70%Capital expenditures: $314,000Capital expenditures$314,000 · 0%$199.7M
Cash from operations
−$60.1M
Capital expenditures
−$314,000
Investments (net)
+$31.0M
Shares issued
+$164.5M
Other financing
+$4.2M
Change in cash
$139.3M

Drawn to scale: where the cash came from and how it was used. Hover for values.

FULC operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

FULC cash flow trends, 2017–2025

Fulcrum Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$20.1M2017−$60.1M2025—
Capital expenditures$1.9M2017$314,0002025−20.2%/yr
Free cash flow−$22.0M2017−$60.4M2025—
Free cash flow margin−5,378.1%2019−3.1%2024+5,375.0 pts
Stock-based compensation$1.4M2017$12.5M2025+31.8%/yr
Dividends paid$02017$68.5M2020—
Share buybacks (net)$02017$193,0002022—
Capex / revenue113.7%20190.3%2024−113.4 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

FULC cash flow by activity

OperatingInvestingFinancingChange in cash

FULC net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

FULC cash flow statement

Fulcrum Therapeutics, Inc. annual cash flow statement
202520242023202220212020201920182017
Operating activities
Net income−$74.9M−$9.7M−$97.3M−$109.9M−$80.8M−$70.8M−$82.7M−$32.6M−$23.0M
Depreciation & amortization$1.4M$1.6M$2.2M$2.4M$2.5M$2.4M$2.1M$1.3M$715,000
Stock-based compensation$12.5M$14.6M$14.8M$13.3M$11.1M$7.3M$4.2M$2.2M$1.4M
Change in working capital$3.9M−$4.2M−$4.6M−$3.1M−$11.9M$7.5M$11.3M$6.5M$804,000
Other non-cash items−$3.0M−$4.4M−$6.0M$152,000$673,000−$68,000$25.6M$0$0
Cash from operating activities−$60.1M−$2.2M−$91.0M−$97.0M−$78.5M−$53.7M−$39.5M−$22.6M−$20.1M
Investing activities
Capital expenditures−$314,000−$278,000−$508,000−$2.0M−$1.7M−$1.3M−$853,000−$9.0M−$1.9M
Investments (net)$31.0M$32.2M−$91.4M$14.4M−$128.0M−$55.8M−$944,000−$9.0M−$1.9M
Acquisitions & other investing$0$278,000$55.2M$0$0$0$853,000$9.0M$1.9M
Cash from investing activities$30.7M$32.2M−$36.7M$12.4M−$129.7M−$57.1M−$944,000−$9.0M−$1.9M
Financing activities
Dividends paid—————−$68.5M—$0$0
Share repurchases & issuance (net)———−$193,000$3.7M−$193,000−$34,000$105.1M$17.7M
Net borrowing (repayment)———−$50,000−$18,000−$50,000−$45,000−$70,000−$70,000
Shares issued$164.5M$0$117.3M$80.8M$182.9M$69.9M$64.2M$105.1M$0
Other financing$4.2M$2.7M$826,000$3.8M$0$69.9M$249,000−$105.1M$70,000
Cash from financing activities$168.7M$2.7M$118.1M$84.3M$186.5M$71.1M$64.3M$105.0M$17.7M
Summary
Net change in cash$139.3M$32.8M−$9.5M−$314,000−$21.6M−$39.7M$23.9M$73.5M−$4.3M
Cash at end of period$198.7M$59.4M$26.7M$36.2M$36.5M$58.1M$97.8M$73.9M$407,000
Free cash flow−$60.4M−$2.5M−$91.5M−$99.0M−$80.2M−$55.0M−$40.3M−$31.5M−$22.0M
Free cash flow margin—−3.1%−3,261.1%−1,561.2%−418.5%−623.3%−5,378.1%——
Capex / revenue—0.3%18.1%31.0%8.9%15.2%113.7%——

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

FULC cash generation

In fiscal 2025 (ended December 31, 2025), Fulcrum Therapeutics generated -$60.1 million of cash from operations and spent $0.3 million on capital expenditures, leaving free cash flow of -$60.4 million. Cash and equivalents rose by $139.3 million over the year.

Related: FULC income statement, FULC balance sheet. See the FULC stock overview for the latest quote and news.

FULC cash flow FAQ

What is Fulcrum Therapeutics's free cash flow?

Fulcrum Therapeutics's free cash flow was -$60.4 million in fiscal 2025: -$60.1 million of operating cash flow minus $0.3 million of capital expenditures It was -$2.5 million a year earlier..

How much cash does Fulcrum Therapeutics generate from operations?

Fulcrum Therapeutics generated -$60.1 million of cash from operating activities in fiscal 2025.

How much does Fulcrum Therapeutics spend on capital expenditures?

Fulcrum Therapeutics spent $0.3 million on capital expenditures in fiscal 2025, compared with $0.3 million the year before.

Biotechnology: cash flow