Caris Life Sciences, Inc. (CAI) Ownership

NASDAQ: CAITop holders, insider trades and short interest.

CAI ownership summary

as of October 18, 2026
Institutions
57.2%
of shares outstanding
Insiders
48.79%
of shares outstanding
Shares outstanding
282.7M
Float
134.9M
shares available to trade
Short interest
12.06%
13.9M shares short
Days to cover
2.68
short interest up 4.2% vs prior month
  • Institutions 57.24%
  • Insiders 48.79%

CAI top institutional holders

20 largest
Caris Life Sciences, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1FMR Inc10.94%30.9M$945.0M+138,293 (+0.4%)June 30, 2026
2J. H. Whitney Equity Partners VI, LLC3.98%11.3M$344.0M−7.0M (−38.3%)June 30, 2026
3Coatue Management LLC3.47%9.8M$300.1M—June 30, 2026
4BRAIDWELL LP2.92%8.3M$252.3M+246,585 (+3.1%)June 30, 2026
5Sixth Street Partners Management Company, L.P.2.59%7.3M$223.9M−7.1M (−49.1%)June 30, 2026
6PointState Capital LP2.42%6.8M$208.7M−531,611 (−7.2%)June 30, 2026
7JPMorgan Chase & Co2.32%6.6M$200.4M+3.1M (+89.5%)June 30, 2026
8BlackRock Inc1.96%5.5M$169.2M+679,686 (+14.0%)June 30, 2026
9T. Rowe Price Investment Management,Inc.1.80%5.1M$155.2M−509,116 (−9.1%)June 30, 2026
10Vanguard Portfolio Management, LLC1.71%4.8M$148.0M+1.1M (+28.9%)June 30, 2026
11Vanguard Capital Management, LLC1.51%4.3M$130.8M+951,217 (+28.6%)June 30, 2026
12Neuberger Berman Group LLC1.27%3.6M$109.7M+377 (+0.0%)June 30, 2026
13Orbimed Advisors LLC0.99%2.8M$85.8M—June 30, 2026
14BNP Paribas Arbitrage, SA0.84%2.4M$72.4M+755,982 (+46.8%)June 30, 2026
15Los Angeles Capital Management LLC0.81%2.3M$70.0M+2.3M (+405,139.3%)March 31, 2026
16Millennium Management LLC0.78%2.2M$67.3M+674,891 (+44.2%)June 30, 2026
17Mak Capital One LLC0.69%1.9M$59.2M+1.9M (0.0%)June 30, 2026
18Morgan Stanley - Brokerage Accounts0.68%1.9M$59.1M+856,114 (+79.3%)June 30, 2026
19Duquesne Family Office LLC0.67%1.9M$57.9M—June 30, 2026
20ClearBridge Advisors, LLC0.56%1.6M$48.8M+44,103 (+2.8%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 13 holders added 12.8M shares and 4 cut 15.1M.

CAI top mutual fund and ETF holders

20 largest
Caris Life Sciences, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Fidelity Contrafund1.44%4.1M$124.4M+996,756 (+32.4%)August 31, 2026
2Vanguard MStar Total Stk Mkt Idx Invest1.44%4.1M$124.0M−9,298 (−0.2%)August 31, 2026
3Vanguard Small Cap Index1.04%2.9M$89.4M+756 (+0.0%)August 31, 2026
4JPMorgan Mid Cap Growth I0.75%2.1M$65.0M−39,450 (−1.8%)August 31, 2026
5Worldwide Healthcare Ord0.71%2.0M$60.9M—June 30, 2026
6Fidelity Select Health Care0.67%1.9M$57.6M−2,267 (−0.1%)August 31, 2026
7Fidelity VIP Mid Cap Initial0.63%1.8M$54.8M+21,949 (+1.2%)August 31, 2026
8Vanguard MStar Small Cap Growth Indx Inv0.60%1.7M$51.5M−5,390 (−0.3%)August 31, 2026
9Strategic Advisers Fidelity US TtlStk0.59%1.7M$51.4M+239,475 (+16.6%)August 31, 2026
10Fidelity VIP Contrafund Initial0.50%1.4M$42.8M+1.3M (+1,468.7%)August 31, 2026
11T. Rowe Price New Horizons0.49%1.4M$41.9M+1.4M (0.0%)August 31, 2026
12Fidelity Advisor New Insights I0.46%1.3M$39.5M+1.2M (+1,141.9%)August 31, 2026
13Fidelity Select Medical Tech and Devcs0.44%1.2M$38.0M−81,967 (−6.2%)August 31, 2026
14American Funds SMALLCAP World A0.42%1.2M$36.1M—June 30, 2026
15iShares Biotechnology ETF0.35%991K$30.3M−7,504 (−0.8%)September 30, 2026
16Fidelity Small Cap Growth0.34%961K$29.4M−81,620 (−7.8%)July 31, 2026
17Fidelity Tactical High Income Sr F80.33%922K$28.2M−227,984 (−19.8%)June 30, 2026
18Fidelity Advisor Health Care I0.32%917K$28.0M−17,118 (−1.8%)August 31, 2026
19JNL/JPMorgan MidCap Growth A0.32%907K$27.7M+442,186 (+95.1%)June 30, 2026
20Nationwide Large Cap Equity Portfolio0.32%902K$27.6M+13,070 (+1.5%)August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

CAI insider transactions

latest 1
Caris Life Sciences, Inc. insider transactions
DateNameTransactionPriceSharesValue
2025-12-11Luke Thomas PowerSell$26.5862,250$1.7M

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

CAI shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns CAI

Institutional investors own 57.2% of Caris Life Sciences's shares and insiders 48.79%. The largest holder is FMR Inc with 10.94% of the shares (30.9M), as of June 30, 2026. Among the top 20 institutions, 13 added shares and 4 reduced their stake in the latest filings. Short interest is 12.06% of the float, or 2.68 days of average trading volume. The share count rose 1,308.5% since 2012.

Related: CAI analyst forecast, CAI key metrics. See the CAI stock overview for the latest quote and news.

CAI ownership FAQ

Who owns the most Caris Life Sciences stock?

The largest shareholders of Caris Life Sciences are FMR Inc (10.94%), J. H. Whitney Equity Partners VI, LLC (3.98%), Coatue Management LLC (3.47%), BRAIDWELL LP (2.92%), Sixth Street Partners Management Company, L.P. (2.59%).

What percentage of Caris Life Sciences is owned by institutions?

Institutions hold 57.2% of Caris Life Sciences's shares outstanding; insiders hold 48.79%.

Which funds own Caris Life Sciences?

The largest fund holders of Caris Life Sciences are Fidelity Contrafund (1.44%), Vanguard MStar Total Stk Mkt Idx Invest (1.44%), Vanguard Small Cap Index (1.04%), JPMorgan Mid Cap Growth I (0.75%), Worldwide Healthcare Ord (0.71%).

What is Caris Life Sciences's short interest?

13.9M shares of Caris Life Sciences were sold short, 12.06% of the float; at the average daily volume it would take 2.68 days to cover.

Are insiders buying or selling Caris Life Sciences?

Of the latest 1 reported insider transactions in Caris Life Sciences (since December 11, 2025), 0 were purchases and 1 were sales.

How many shares of Caris Life Sciences are outstanding?

Caris Life Sciences has 282.7M shares outstanding, of which 134.9M are in the public float.

Biotechnology: ownership