Neurogene Inc. (NGNE) Key Metrics

NASDAQ: NGNEValuation, returns, debt and efficiency ratios over 10 years.

NGNE valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$465.3M
Enterprise value
$402.3M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
438.7
Price / book
2.9
10-yr median 14.0
EV / EBITDA
—
Dividend yield
—
Beta
2.09

NGNE key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

NGNE valuation Price multiples at each fiscal year-end price.

Price / book+27.2%
1.6
2025 · hover or tap a bar for each year
2016: 43.1 (+48.2%)2017: 55.8 (+29.3%)2018: 14.0 (−74.9%)2019: 47.0 (+236.2%)2020: 76.4 (+62.6%)2022: 1.32023: 1.3 (+0.9%)2024: 1.3 (−3.2%)2025: 1.6 (+27.2%)
20162025
Free cash flow yield−0.2 pts
−18.0%
2025 · hover or tap a bar for each year
2016: −0.5% (+0.1 pts)2017: −0.8% (−0.3 pts)2018: −3.1% (−2.3 pts)2019: −0.2% (+2.9 pts)2020: −0.2% (+0.1 pts)2021: −1.2% (−1.0 pts)2022: −42.2% (−41.0 pts)2023: −20.8% (+21.4 pts)2024: −17.8% (+3.0 pts)2025: −18.0% (−0.2 pts)
20162025

NGNE valuation history

Fiscal year-endToday10-year median

NGNE returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

NGNE debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

NGNE price vs earnings per share

Share price at year-endEPS (right axis)

NGNE key metrics

2016–2025
Neurogene Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$436.1M$401.6M$248.5M$130.5M$5.31B$14.61B$6.66B$1.02B$5.52B$6.24B
Enterprise value$176.9M$101.6M$67.6M$53.2M$5.24B$14.43B$6.52B$939.1M$5.41B$6.14B
Price / sales—434.1—————40.6——
Price / book1.61.31.31.3—76.447.014.055.843.1
EV / sales—109.8—————37.6——
Earnings yield−20.7%−18.7%−14.6%−42.3%−1.0%−0.2%−1.0%−3.1%−0.9%−0.6%
Free cash flow yield−18.0%−17.8%−20.8%−42.2%−1.2%−0.2%−0.2%−3.1%−0.8%−0.5%
Share price at fiscal year-end$20.60$22.86$19.38$10.18$96.40$282.00$246.40$43.20$235.20$330.20
Per share
Revenue per share$0.00$0.05$0.00$0.00$0.00$0.00$0.00$1.06$0.00$0.00
Earnings per share−$4.27−$4.28−$2.83−$4.30−$0.92−$0.64−$2.57−$1.34−$2.14−$1.96
Operating cash flow per share−$3.65−$4.02−$4.01−$4.12−$0.84−$0.47−$0.57−$1.34−$1.91−$1.60
Free cash flow per share−$3.70−$4.07−$4.03−$4.29−$1.18−$0.52−$0.60−$1.34−$1.93−$1.64
Cash per share$12.71$17.78$15.37$6.40$1.28$3.72$5.29$3.27$4.61$5.45
Book value per share$12.51$17.67$14.51$7.69−$1.67$3.69$5.24$3.09$4.22$7.66
Tangible book value per share$12.51$17.67$14.51$7.69−$1.67$3.68$5.22$3.09$4.22$7.66
Capex per share$0.06$0.05$0.03$0.17$0.33$0.04$0.03$0.00$0.02$0.04
Debt per share$0.47$0.71$1.27$0.37$0.12$0.23$0.04$0.00$0.00$0.00
Shares outstanding21.2M17.6M12.8M12.8M55.0M51.8M27.0M23.5M23.5M18.9M
Change in shares outstanding+20.5%+37.0%0.0%−76.7%+6.2%+91.7%+14.9%+0.3%+24.1%+49.5%
Returns & profitability
Return on equity (ROE)−31.4%−30.3%−25.5%——−20.0%−64.8%−36.8%−41.2%−29.2%
Return on invested capital (ROIC)—−841.0%−332.4%——−620.2%———−78.6%
Return on assets (ROA)−28.9%−26.9%−21.9%−52.4%−32.4%−18.6%−61.8%−33.6%−37.9%−27.6%
Return on tangible assets−31.3%−22.4%−16.3%−50.5%−49.8%−15.8%−47.4%−40.7%−45.5%−24.0%
Free cash flow margin———————−126.5%——
Financial health
Total debt$9.9M$12.4M$16.3M$4.7M$6.4M$12.1M$1.2M$6,000$32,999$47,000
Cash & short-term investments$269.0M$312.4M$197.2M$82.0M$70.5M$192.6M$143.1M$76.9M$108.1M$103.1M
Net debt−$259.1M−$300.0M−$180.9M−$77.3M−$64.1M−$180.4M−$141.9M−$76.9M−$108.1M−$103.0M
Debt / equity0.040.040.090.05—0.060.010.000.000.00
Debt / assets0.030.040.070.040.060.060.010.000.000.00
Current ratio16.5620.848.7212.746.8124.6630.2816.689.9310.87
Quick ratio16.5620.848.6612.586.6424.6630.2816.689.9310.87
Working capital$255.4M$300.8M$177.4M$78.1M$63.1M$186.6M$138.9M$72.5M$97.9M$94.0M
Invested capital$5.8M$10.4M$5.1M$21.3M−$156.0M$10.8M−$195,000−$4.2M−$9.2M$41.7M
Tangible asset value$264.9M$310.4M$186.0M$98.6M−$92.0M$190.9M$141.1M$72.7M$98.9M$144.7M
Net current asset value$248.1M$290.6M$163.8M$74.1M−$119.4M$175.2M$138.3M$72.2M$97.4M$93.8M
Graham net-net per share$11.59$16.37$12.62$5.67−$2.20$3.34$5.10$3.06$4.12$4.94
Capital allocation
Capex / revenue—87.4%—————0.2%——
Capex / depreciation0.380.250.100.7019.401.222.59—494,000.00713,000.00
Stock-based compensation / revenue—899.5%————————
R&D / revenue—6,585.6%—————131.2%——
SG&A / revenue—2,444.6%————————
Efficiency
Days sales outstanding—246.2————————
Days of inventory on hand——144.0170.816.5—————
Days payables outstanding188.0221.0180.2357.230.0293.31,237.8———
Cash conversion cycle (days)—25.2————————
Receivables turnover—1.480.000.000.00—————
Payables turnover1.941.652.031.0212.161.240.290.00——
Inventory turnover——2.532.1422.09—————
Asset turnover0.000.000.000.000.000.000.000.270.000.00
Average receivables—$624,000$795,000$890,000$790,000—————
Average payables$1.6M$2.0M$1.6M$3.1M$3.5M$1.5M$1.2M$702,000——
Average inventory——$1.3M$1.5M$1.9M—————
Intangibles / total assets0.0%0.0%0.0%0.0%0.1%0.2%0.4%0.0%0.0%0.0%

Computed from NGNE's annual financial statements (latest annual report filed March 24, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

NGNE valuation and financial ratios

Neurogene earned a return on equity of −31.4% in fiscal 2025. It ended the year with $9.9 million of debt and $269.0 million in cash and short-term investments, a net cash position of $259.1 million. The share count rose 12.0% from 18.9M to 21.2M over 9 years.

See the NGNE income statement, the NGNE chart for price history, or the NGNE stock overview for the latest quote and news.

NGNE key metrics FAQ

What is Neurogene's return on equity?

Neurogene's return on equity (ROE) was −31.4% in fiscal 2025: net income of -$90.4 million on average shareholders' equity of $287.6 million.

How much debt does Neurogene have?

Neurogene had total debt of $9.9 million at the end of fiscal 2025, a debt-to-equity ratio of 0.04 and more cash than debt.

What is Neurogene's free cash flow yield?

Neurogene generated -$78.4 million of free cash flow in fiscal 2025, a free cash flow yield of −18.0% on its market value at year-end ($436.1 million).

What is Neurogene's current ratio?

Neurogene's current ratio was 16.56 at the end of fiscal 2025: current assets were 16.56 times current liabilities.

Biotechnology key metrics