SPDR S&P Biotech ETF (XBI) Performance
XBI total return
Distributions reinvested · as of Oct 23, 2026- YTD
- +22.8% since Dec 31, 2025
- 1 year
- +39.6% total return
- 5 years
- +3.9% a year
- 10 years
- +9.8% a year
- Since first price
- +11.6% a year since 2006
XBI trailing returns vs SPY, QQQ, AGG
| Period | XBI total return | Price only | S&P 500 (SPY) | Nasdaq-100 (QQQ) | U.S. bonds (AGG) |
|---|---|---|---|---|---|
| 1 month | −3.6% | −3.6% | −1.0% | −5.0% | +0.9% |
| 3 months | −1.8% | −1.8% | +3.2% | +1.9% | −0.4% |
| 6 months | +11.3% | +11.2% | +7.8% | +8.4% | −1.5% |
| YTD | +22.8% | +22.6% | +12.3% | +15.1% | −1.0% |
| 1 year | +39.6% | +39.0% | +14.4% | +15.9% | −1.1% |
| 3 years | +129.9%+32.0%/yr | +128.4% | +87.4%+23.3%/yr | +101.4%+26.3%/yr | +16.6%+5.2%/yr |
| 5 years | +21.2%+3.9%/yr | +20.4% | +79.3%+12.4%/yr | +94.0%+14.2%/yr | −0.8%−0.2%/yr |
| 10 years | +153.9%+9.8%/yr | +150.4% | +315.9%+15.3%/yr | +538.9%+20.4%/yr | +14.0%+1.3%/yr |
| 15 years | +618.9%+14.1%/yr | +591.9% | +696.0%+14.8%/yr | +1,299.3%+19.2%/yr | +32.2%+1.9%/yr |
| 20 years | +851.7%+11.9%/yr | +799.4% | +696.9%+10.9%/yr | +1,839.9%+16.0%/yr | +79.6%+3.0%/yr |
| Since inceptionFeb 6, 2006 | +863.9%+11.6%/yr | +810.9% | — | — | — |
Total return from adjusted closes (distributions reinvested, before tax). Periods of 3 years or more are also shown annualized. Price only excludes distributions.
Growth of $10,000: XBI vs SPY
From Feb 6, 2006: XBI grew to $96,389, SPY to $87,641.
Year-end values with distributions reinvested, no taxes or trading costs. Start: first common trading day of both funds.
XBI returns by calendar year
14 of 19 full years positive. Best 2013 (+48.4%), worst 2022 (−25.9%). 2026 is year to date.
XBI annual returns table
| Year | XBI | Largest drop | SPY | QQQ | AGG |
|---|---|---|---|---|---|
| 2026YTD | +22.8% | −14.9% | +12.3% | +15.1% | −1.0% |
| 2025 | +35.9% | −26.3% | +17.7% | +20.8% | +7.2% |
| 2024 | +1.0% | −20.1% | +24.9% | +25.6% | +1.3% |
| 2023 | +7.6% | −30.3% | +26.2% | +54.9% | +5.7% |
| 2022 | −25.9% | −45.6% | −18.2% | −32.6% | −13.0% |
| 2021 | −20.4% | −37.5% | +28.7% | +27.4% | −1.8% |
| 2020 | +48.3% | −32.9% | +18.3% | +48.6% | +7.5% |
| 2019 | +32.6% | −20.4% | +31.2% | +39.0% | +8.5% |
| 2018 | −15.3% | −35.3% | −4.6% | −0.1% | +0.1% |
| 2017 | +43.8% | −9.7% | +21.7% | +32.7% | +3.6% |
| 2016 | −15.4% | −32.6% | +12.0% | +7.1% | +2.4% |
| 2015 | +13.6% | −33.5% | +1.2% | +9.4% | +0.5% |
| 2014 | +45.0% | −29.1% | +13.5% | +19.2% | +6.0% |
| 2013 | +48.4% | −13.4% | +32.3% | +36.6% | −2.0% |
| 2012 | +32.7% | −15.1% | +16.0% | +18.1% | +3.8% |
| 2011 | +5.3% | −26.7% | +1.9% | +3.4% | +7.7% |
| 2010 | +17.6% | −19.5% | +15.1% | +19.9% | +6.4% |
| 2009 | +0.4% | −22.9% | +26.4% | +54.7% | +3.0% |
| 2008 | −8.6% | −35.5% | −36.8% | −41.7% | +7.9% |
| 2007 | +29.0% | −8.9% | +5.1% | +19.0% | +6.6% |
Largest drop = deepest fall from a high within that calendar year.
Calendar-year return vs largest drop within the year
Most years include a sizable fall at some point even when the year ends higher.
XBI largest drawdowns
Now 13.5% below the high| Peak | Decline | Bottom | Recovered | Fall | Underwater |
|---|---|---|---|---|---|
| Feb 8, 2021 | −63.9% | May 11, 2022 | not yet | 1.3 years | 5.7 years so far |
| Jul 17, 2015 | −49.2% | Feb 11, 2016 | Jan 12, 2018 | 7 months | 2.5 years |
| Aug 14, 2008 | −37.6% | Mar 5, 2009 | Apr 14, 2011 | 7 months | 2.7 years |
| Jun 20, 2018 | −35.3% | Dec 24, 2018 | May 11, 2020 | 6 months | 1.9 years |
| Feb 27, 2014 | −29.1% | May 8, 2014 | Oct 28, 2014 | 2 months | 8 months |
| Jul 22, 2011 | −26.7% | Aug 8, 2011 | Jan 27, 2012 | 17 days | 6 months |
Declines from a closing high (distributions reinvested) of 10% or more. Underwater = time from the peak until the old high was regained.
XBI risk statistics
| Statistic | 3 years | 5 years | 10 years | Since 2006 |
|---|---|---|---|---|
| Annualized return | +29.5% | +4.8% | +9.2% | +11.5% |
| Volatility (annualized) | 25.6% | 26.0% | 27.0% | 26.9% |
| Sharpe ratio | 0.97 | 0.17 | 0.38 | — |
| Sortino ratio | 1.84 | 0.25 | 0.59 | — |
| Best month | +18.3% | +18.3% | +20.6% | +20.6% |
| Worst month | −10.8% | −17.9% | −17.9% | −28.0% |
| Best 12 months | +91.7% | +91.7% | +91.7% | +91.7% |
| Worst 12 months | −14.4% | −36.9% | −46.3% | −46.3% |
| Positive months | 64% | 55% | 56% | 56% |
| Beta vs S&P 500 | 1.04 | 0.83 | 1.01 | — |
| Correlation with S&P 500 | 0.50 | 0.50 | 0.57 | — |
From monthly total returns. Sharpe and Sortino use 1–3 month T-bills (BIL) as the risk-free rate, so they need history from 2007 on.
XBI rolling returns
| Holding period | Periods | Worst | Median | Best | Positive |
|---|---|---|---|---|---|
| 1-year | 237 | −46.3% | +17.3% | +91.7% | 71% |
| 3-year (a year) | 213 | −17.2% | +11.3% | +44.4% | 80% |
| 5-year (a year) | 189 | −5.7% | +11.3% | +37.8% | 84% |
| 10-year (a year) | 129 | +0.0% | +14.7% | +22.6% | 100% |
Every holding period starting at a month-end since 2006. Returns for 3 years and longer are annualized.
XBI performance overview
SPDR S&P Biotech ETF (XBI) returned +39.6% over the past year and +9.8% a year over ten years, with distributions reinvested. Since its first recorded price in 2006 it has returned +11.6% a year, turning $10,000 into about $96,389. Over the same year S&P 500 (SPY) returned +14.4%.
The deepest decline was −63.9%, from Feb 8, 2021 to May 11, 2022; the fund has not yet regained that high. XBI finished 14 of its 19 full calendar years with a gain; the best year was 2013 (+48.4%) and the worst 2022 (−25.9%). Volatility has been 26.9% a year.
Related: XBI chart, XBI holdings, XBI dividends. See the XBI overview for the latest quote and fund facts.
XBI performance FAQ
What is the XBI return over the past year?
XBI returned +39.6% over the 12 months to October 23, 2026, including reinvested distributions. On price alone it rose 39.0%.
What is the average annual return of XBI?
XBI has returned +3.9% a year over 5 years, +9.8% a year over 10 years, +11.6% a year since February 6, 2006 (total return, distributions reinvested).
How much would $10,000 invested in XBI be worth?
$10,000 invested in XBI at its first recorded close on February 6, 2006 would be worth about $96,389 on October 23, 2026 with distributions reinvested.
What was the worst year for XBI?
The worst calendar year was 2022, with a total return of −25.9%. The best was 2013 at +48.4%.
What is the biggest drawdown of XBI?
The largest peak-to-trough decline was −63.9% between February 8, 2021 and May 11, 2022. It has not yet recovered to that high; it is 13.5% below its peak.
How volatile is XBI?
Over the past 3 years XBI had an annualized volatility of 25.6% and a Sharpe ratio of 0.97 (excess return over 1–3 month T-bills per unit of risk).