Direxion Daily Pharmaceutical & Medical Bull… (PILL) Performance

NYSE Arca: PILLTotal returns, calendar years, drawdowns and risk since 2017.

PILL total return

Distributions reinvested · as of Oct 23, 2026
YTD
+13.2%
since Dec 31, 2025
1 year
+69.1%
total return
5 years
−4.3%
a year
Since first price
−5.0%
a year since 2017

PILL trailing returns vs SPY, QQQ, AGG

PILL trailing returns
PeriodPILL total returnPrice onlyS&P 500 (SPY)Nasdaq-100 (QQQ)U.S. bonds (AGG)
1 month−17.5%−17.5%−1.0%−5.0%+0.9%
3 months−27.6%−27.6%+3.2%+1.9%−0.4%
6 months+15.1%+15.0%+7.8%+8.4%−1.5%
YTD+13.2%+13.0%+12.3%+15.1%−1.0%
1 year+69.1%+68.3%+14.4%+15.9%−1.1%
3 years+169.4%+39.2%/yr+161.3%+87.4%+23.3%/yr+101.4%+26.3%/yr+16.6%+5.2%/yr
5 years−19.7%−4.3%/yr−23.5%+79.3%+12.4%/yr+94.0%+14.2%/yr−0.8%−0.2%/yr
Since inceptionNov 15, 2017−36.8%−5.0%/yr−40.6%———

Total return from adjusted closes (distributions reinvested, before tax). Periods of 3 years or more are also shown annualized. Price only excludes distributions.

Growth of $10,000: PILL vs SPY

PILLS&P 500 (SPY)

From Nov 15, 2017: PILL grew to $6,320, SPY to $34,014.

Year-end values with distributions reinvested, no taxes or trading costs. Start: first common trading day of both funds.

PILL returns by calendar year

PILLSPY

3 of 8 full years positive. Best 2025 (+75.1%), worst 2022 (−43.2%). 2026 is year to date.

PILL annual returns table

PILL calendar-year returns
YearPILLLargest dropSPYQQQAGG
2026YTD+13.2%−43.8%+12.3%+15.1%−1.0%
2025+75.1%−51.3%+17.7%+20.8%+7.2%
2024−7.3%−38.4%+24.9%+25.6%+1.3%
2023−12.1%−56.3%+26.2%+54.9%+5.7%
2022−43.2%−48.8%−18.2%−32.6%−13.0%
2021−37.3%−56.7%+28.7%+27.4%−1.8%
2020+0.3%−76.0%+18.3%+48.6%+7.5%
2019+19.3%−60.0%+31.2%+39.0%+8.5%
2018−21.1%−52.8%−4.6%−0.1%+0.1%

Largest drop = deepest fall from a high within that calendar year.

Calendar-year return vs largest drop within the year

Calendar-year returnLargest drop within the year

Most years include a sizable fall at some point even when the year ends higher.

PILL largest drawdowns

Now 61.2% below the high
PILL largest drawdowns
PeakDeclineBottomRecoveredFallUnderwater
Aug 29, 2018−88.8%Apr 10, 2025not yet6.6 years8.2 years so far
Jan 29, 2018−42.9%May 3, 2018Aug 20, 20183 months7 months

Declines from a closing high (distributions reinvested) of 10% or more. Underwater = time from the peak until the old high was regained.

PILL risk statistics

PILL risk statistics
Statistic3 years5 yearsSince 2017
Annualized return+31.7%−1.2%−4.9%
Volatility (annualized)64.1%58.0%60.5%
Sharpe ratio0.660.190.17
Sortino ratio1.230.310.27
Best month+48.8%+48.8%+50.2%
Worst month−28.5%−28.5%−44.6%
Best 12 months+254.4%+254.4%+254.4%
Worst 12 months−30.6%−49.7%−66.6%
Positive months58%53%52%
Beta vs S&P 5001.721.79—
Correlation with S&P 5000.330.48—

From monthly total returns. Sharpe and Sortino use 1–3 month T-bills (BIL) as the risk-free rate, so they need history from 2007 on.

PILL rolling returns

PILL rolling returns
Holding periodPeriodsWorstMedianBestPositive
1-year96−66.6%−10.8%+254.4%40%
3-year (a year)72−35.3%−15.0%+40.9%18%
5-year (a year)48−28.5%−16.8%+2.8%2%

Every holding period starting at a month-end since 2017. Returns for 3 years and longer are annualized.

PILL performance overview

Direxion Daily Pharmaceutical & Medical Bull… (PILL) returned +69.1% over the past year and −4.3% a year over five years, with distributions reinvested. Since its first recorded price in 2017 it has returned −5.0% a year, turning $10,000 into about $6,320. Over the same year S&P 500 (SPY) returned +14.4%.

The deepest decline was −88.8%, from Aug 29, 2018 to Apr 10, 2025; the fund has not yet regained that high. PILL finished 3 of its 8 full calendar years with a gain; the best year was 2025 (+75.1%) and the worst 2022 (−43.2%). Volatility has been 60.5% a year.

Related: PILL chart, PILL dividends. See the PILL overview for the latest quote and fund facts.

PILL performance FAQ

What is the PILL return over the past year?

PILL returned +69.1% over the 12 months to October 23, 2026, including reinvested distributions. On price alone it rose 68.3%.

What is the average annual return of PILL?

PILL has returned −4.3% a year over 5 years, −5.0% a year since November 15, 2017 (total return, distributions reinvested).

How much would $10,000 invested in PILL be worth?

$10,000 invested in PILL at its first recorded close on November 15, 2017 would be worth about $6,320 on October 23, 2026 with distributions reinvested.

What was the worst year for PILL?

The worst calendar year was 2022, with a total return of −43.2%. The best was 2025 at +75.1%.

What is the biggest drawdown of PILL?

The largest peak-to-trough decline was −88.8% between August 29, 2018 and April 10, 2025. It has not yet recovered to that high; it is 61.2% below its peak.

How volatile is PILL?

Over the past 3 years PILL had an annualized volatility of 64.1% and a Sharpe ratio of 0.66 (excess return over 1–3 month T-bills per unit of risk).