iShares Genomics Immunology and Healthcare ETF (IDNA) Performance
IDNA total return
Distributions reinvested · as of Oct 23, 2026- YTD
- +56.9% since Dec 31, 2025
- 1 year
- +68.5% total return
- 5 years
- −2.8% a year
- Since first price
- +7.8% a year since 2019
IDNA trailing returns vs SPY, QQQ, AGG
| Period | IDNA total return | Price only | S&P 500 (SPY) | Nasdaq-100 (QQQ) | U.S. bonds (AGG) |
|---|---|---|---|---|---|
| 1 month | +0.3% | +0.3% | −1.0% | −5.0% | +0.9% |
| 3 months | +26.5% | +26.5% | +3.2% | +1.9% | −0.4% |
| 6 months | +35.7% | +35.2% | +7.8% | +8.4% | −1.5% |
| YTD | +56.9% | +56.2% | +12.3% | +15.1% | −1.0% |
| 1 year | +68.5% | +66.8% | +14.4% | +15.9% | −1.1% |
| 3 years | +137.9%+33.5%/yr | +130.0% | +87.4%+23.3%/yr | +101.4%+26.3%/yr | +16.6%+5.2%/yr |
| 5 years | −13.2%−2.8%/yr | −17.2% | +79.3%+12.4%/yr | +94.0%+14.2%/yr | −0.8%−0.2%/yr |
| Since inceptionJun 13, 2019 | +74.3%+7.8%/yr | +64.2% | — | — | — |
Total return from adjusted closes (distributions reinvested, before tax). Periods of 3 years or more are also shown annualized. Price only excludes distributions.
Growth of $10,000: IDNA vs SPY
From Jun 13, 2019: IDNA grew to $17,429, SPY to $29,281.
Year-end values with distributions reinvested, no taxes or trading costs. Start: first common trading day of both funds.
IDNA returns by calendar year
2 of 6 full years positive. Best 2020 (+54.3%), worst 2022 (−42.3%). 2026 is year to date.
IDNA annual returns table
| Year | IDNA | Largest drop | SPY | QQQ | AGG |
|---|---|---|---|---|---|
| 2026YTD | +56.9% | −10.7% | +12.3% | +15.1% | −1.0% |
| 2025 | +17.3% | −24.2% | +17.7% | +20.8% | +7.2% |
| 2024 | −0.7% | −13.8% | +24.9% | +25.6% | +1.3% |
| 2023 | −7.6% | −37.6% | +26.2% | +54.9% | +5.7% |
| 2022 | −42.3% | −44.5% | −18.2% | −32.6% | −13.0% |
| 2021 | −4.0% | −22.2% | +28.7% | +27.4% | −1.8% |
| 2020 | +54.3% | −26.9% | +18.3% | +48.6% | +7.5% |
Largest drop = deepest fall from a high within that calendar year.
Calendar-year return vs largest drop within the year
Most years include a sizable fall at some point even when the year ends higher.
IDNA largest drawdowns
Now 22.7% below the high| Peak | Decline | Bottom | Recovered | Fall | Underwater |
|---|---|---|---|---|---|
| Sep 2, 2021 | −68.3% | Oct 27, 2023 | not yet | 2.1 years | 5.1 years so far |
| Mar 4, 2020 | −26.9% | Mar 16, 2020 | Apr 17, 2020 | 12 days | 44 days |
| Feb 8, 2021 | −22.2% | Mar 8, 2021 | Aug 9, 2021 | 28 days | 6 months |
| Jul 18, 2019 | −14.4% | Oct 9, 2019 | Nov 20, 2019 | 3 months | 4 months |
| Jul 20, 2020 | −13.6% | Sep 8, 2020 | Oct 9, 2020 | 50 days | 3 months |
Declines from a closing high (distributions reinvested) of 10% or more. Underwater = time from the peak until the old high was regained.
IDNA risk statistics
| Statistic | 3 years | 5 years | Since 2019 |
|---|---|---|---|
| Annualized return | +29.1% | −2.6% | +7.2% |
| Volatility (annualized) | 24.8% | 25.9% | 26.1% |
| Sharpe ratio | 0.98 | -0.12 | 0.29 |
| Sortino ratio | 1.95 | -0.16 | 0.47 |
| Best month | +21.4% | +21.4% | +21.4% |
| Worst month | −11.0% | −17.1% | −17.1% |
| Best 12 months | +81.0% | +81.0% | +81.0% |
| Worst 12 months | −14.1% | −47.4% | −47.4% |
| Positive months | 61% | 50% | 53% |
| Beta vs S&P 500 | 0.83 | 0.93 | — |
| Correlation with S&P 500 | 0.42 | 0.56 | — |
From monthly total returns. Sharpe and Sortino use 1–3 month T-bills (BIL) as the risk-free rate, so they need history from 2007 on.
IDNA rolling returns
| Holding period | Periods | Worst | Median | Best | Positive |
|---|---|---|---|---|---|
| 1-year | 77 | −47.4% | +1.6% | +81.0% | 53% |
| 3-year (a year) | 53 | −23.2% | −10.0% | +32.7% | 32% |
| 5-year (a year) | 29 | −10.9% | −7.1% | +0.8% | 7% |
Every holding period starting at a month-end since 2019. Returns for 3 years and longer are annualized.
IDNA performance overview
iShares Genomics Immunology and Healthcare ETF (IDNA) returned +68.5% over the past year and −2.8% a year over five years, with distributions reinvested. Since its first recorded price in 2019 it has returned +7.8% a year, turning $10,000 into about $17,429. Over the same year S&P 500 (SPY) returned +14.4%.
The deepest decline was −68.3%, from Sep 2, 2021 to Oct 27, 2023; the fund has not yet regained that high. IDNA finished 2 of its 6 full calendar years with a gain; the best year was 2020 (+54.3%) and the worst 2022 (−42.3%). Volatility has been 26.1% a year.
Related: IDNA chart, IDNA holdings, IDNA dividends. See the IDNA overview for the latest quote and fund facts.
IDNA performance FAQ
What is the IDNA return over the past year?
IDNA returned +68.5% over the 12 months to October 23, 2026, including reinvested distributions. On price alone it rose 66.8%.
What is the average annual return of IDNA?
IDNA has returned −2.8% a year over 5 years, +7.8% a year since June 13, 2019 (total return, distributions reinvested).
How much would $10,000 invested in IDNA be worth?
$10,000 invested in IDNA at its first recorded close on June 13, 2019 would be worth about $17,429 on October 23, 2026 with distributions reinvested.
What was the worst year for IDNA?
The worst calendar year was 2022, with a total return of −42.3%. The best was 2020 at +54.3%.
What is the biggest drawdown of IDNA?
The largest peak-to-trough decline was −68.3% between September 2, 2021 and October 27, 2023. It has not yet recovered to that high; it is 22.7% below its peak.
How volatile is IDNA?
Over the past 3 years IDNA had an annualized volatility of 24.8% and a Sharpe ratio of 0.98 (excess return over 1–3 month T-bills per unit of risk).