Synlogic, Inc. (SYBX) Ownership

OTC Pink: SYBXTop holders, insider trades and short interest.

SYBX ownership summary

as of October 21, 2026
Institutions
57.6%
of shares outstanding
Insiders
15.65%
of shares outstanding
Shares outstanding
12.2M
Float
4.0M
shares available to trade
Short interest
0.15%
10K shares short
Days to cover
0.29
short interest up 9.7% vs prior month
  • Institutions 57.55%
  • Insiders 15.65%
  • Other investors 26.80%

SYBX top institutional holders

20 largest
Synlogic, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1DRW Securities, LLC0.20%24K$25,664−600 (−2.5%)March 31, 2026
2State Street Corp0.00%——−10,176 (−100.0%)March 31, 2026
3Ikarian Capital, LLC0.00%——−19,966 (−100.0%)March 31, 2026
4Susquehanna International Group, LLP0.00%——−11,623 (−100.0%)March 31, 2026
5BlackRock Inc0.00%——−19,757 (−100.0%)March 31, 2026
6Jane Street Group LLC0.00%——−14,998 (−100.0%)March 31, 2026
7Northern Trust Corp0.00%——−19,469 (−100.0%)March 31, 2026
8FMR Inc0.00%——−5,323 (−100.0%)March 31, 2026
9FLAGSHIP HARBOR ADVISORS, LLC0.00%——−1,033 (−100.0%)March 31, 2026
10Citigroup Inc0.00%——−1 (−100.0%)March 31, 2026
11Citadel Advisors Llc0.00%——−141,608 (−100.0%)March 31, 2026
12UBS Group AG0.00%——−2,531 (−100.0%)March 31, 2026
13Danske Bank A/S.0.00%——−1 (−100.0%)March 31, 2026
14Renaissance Technologies Corp0.00%——−85,627 (−100.0%)March 31, 2026
15BNP Paribas Arbitrage, SA0.00%——−24 (−100.0%)March 31, 2026
16Morgan Stanley - Brokerage Accounts0.00%——−1,095 (−100.0%)March 31, 2026
17Geode Capital Management, LLC0.00%——−71,645 (−100.0%)March 31, 2026
18JPMorgan Chase & Co0.00%——−1 (−100.0%)March 31, 2026
19Cable Car Capital LLC0.00%——−3.3M (−100.0%)March 31, 2026
20NEA Management Company, LLC0.00%——−2.9M (−100.0%)March 31, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 0 holders added 0 shares and 20 cut 6.6M.

SYBX top mutual fund and ETF holders

3 largest
Synlogic, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Pacific Select Large-Cap Growth I0.04%5,323$5,749—August 31, 2026
2Extended Equity Market Fund B0.02%2,557$2,762—December 31, 2025
3Extended Equity Market Fund E0.02%2,557$2,762—December 31, 2025

Funds report holdings monthly or quarterly; dates differ by fund.

SYBX insider transactions

latest 1
Synlogic, Inc. insider transactions
DateNameTransactionPriceSharesValue
2025-10-29Mary Beth DooleySell$1.81157$284

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

SYBX shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns SYBX

Institutional investors own 57.6% of Synlogic's shares and insiders 15.65%. The largest holder is DRW Securities, LLC with 0.20% of the shares (24K), as of March 31, 2026. Among the top 20 institutions, 0 added shares and 20 reduced their stake in the latest filings. Short interest is 0.15% of the float, or 0.29 days of average trading volume. The share count rose 10,766.6% since 2014.

Related: SYBX analyst forecast, SYBX key metrics. See the SYBX stock overview for the latest quote and news.

SYBX ownership FAQ

Who owns the most Synlogic stock?

The largest shareholders of Synlogic are DRW Securities, LLC (0.20%), State Street Corp (0.00%), Ikarian Capital, LLC (0.00%), Susquehanna International Group, LLP (0.00%), BlackRock Inc (0.00%).

What percentage of Synlogic is owned by institutions?

Institutions hold 57.6% of Synlogic's shares outstanding; insiders hold 15.65%.

Which funds own Synlogic?

The largest fund holders of Synlogic are Pacific Select Large-Cap Growth I (0.04%), Extended Equity Market Fund B (0.02%), Extended Equity Market Fund E (0.02%).

What is Synlogic's short interest?

10K shares of Synlogic were sold short, 0.15% of the float; at the average daily volume it would take 0.29 days to cover.

Are insiders buying or selling Synlogic?

Of the latest 1 reported insider transactions in Synlogic (since October 29, 2025), 0 were purchases and 1 were sales.

How many shares of Synlogic are outstanding?

Synlogic has 12.2M shares outstanding, of which 4.0M are in the public float.

Biotechnology: ownership