uniQure N.V. (QURE) Ownership

NASDAQ: QURETop holders, insider trades and short interest.

QURE ownership summary

as of October 18, 2026
Institutions
98.1%
of shares outstanding
Insiders
1.26%
of shares outstanding
Shares outstanding
69.4M
Float
57.5M
shares available to trade
Short interest
12.73%
8.7M shares short
Days to cover
2.90
short interest down 12.1% vs prior month
  • Institutions 98.10%
  • Insiders 1.26%
  • Other investors 0.64%

QURE top institutional holders

20 largest
uniQure N.V. top institutional holders
#Holder% of sharesSharesValueChangeReported
1venBio Select Advisor LLC9.70%6.7M$146.5M+768,182 (+12.9%)June 30, 2026
2JPMorgan Chase & Co7.02%4.9M$106.0M+2.0M (+71.6%)June 30, 2026
3RTW INVESTMENTS, LLC5.68%3.9M$85.8M+1.4M (+52.4%)June 30, 2026
4State Street Corp4.19%2.9M$63.2M+643,313 (+28.5%)June 30, 2026
5Aberdeen Group PLC4.11%2.8M$62.0M−2.5M (−46.3%)June 30, 2026
6BlackRock Inc2.71%1.9M$40.9M+143,995 (+8.3%)June 30, 2026
7Orbimed Advisors LLC2.61%1.8M$39.4M−328,663 (−15.4%)June 30, 2026
8Jane Street Group LLC2.32%1.6M$35.1M+974,488 (+153.2%)June 30, 2026
9Jennison Associates LLC2.25%1.6M$34.0M+327,623 (+26.6%)June 30, 2026
10Boxer Capital Management, LLC2.17%1.5M$32.7M+841,300 (+127.1%)June 30, 2026
11The Goldman Sachs Group Inc2.13%1.5M$32.1M+212,720 (+16.8%)June 30, 2026
12Two Sigma Investments LLC2.11%1.5M$31.8M−1.2M (−45.4%)June 30, 2026
13Two Seas Capital LP1.87%1.3M$28.3M+1.3M (0.0%)March 31, 2026
14FMR Inc1.83%1.3M$27.7M−473,740 (−27.2%)June 30, 2026
15Mak Capital One LLC1.78%1.2M$26.8M+790,846 (+179.2%)June 30, 2026
16MPM Oncology Impact Management LP1.77%1.2M$26.7M−143,376 (−10.5%)June 30, 2026
17Morgan Stanley - Brokerage Accounts1.54%1.1M$23.2M+700,522 (+191.3%)June 30, 2026
18Assenagon Asset Management SA1.48%1.0M$22.4M+880,311 (+599.9%)June 30, 2026
19Vestal Point Capital LP1.35%935K$20.4M+576,004 (+160.4%)June 30, 2026
20Maverick Capital Ltd1.33%925K$20.2M+227,743 (+32.6%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 15 holders added 11.8M shares and 5 cut 4.6M.

QURE top mutual fund and ETF holders

20 largest
uniQure N.V. top fund holders
#Holder% of sharesSharesValueChangeReported
1State Street® SPDR® S&P® Biotech ETF2.95%2.0M$44.5M−38,900 (−1.9%)September 30, 2026
2JPMorgan Growth Advantage A2.52%1.7M$38.0M−25,480 (−1.4%)August 31, 2026
3JPMorgan Mid Cap Growth I1.77%1.2M$26.7M−22,771 (−1.8%)August 31, 2026
4Worldwide Healthcare Ord1.08%746K$16.2M—June 30, 2026
5iShares Biotechnology ETF0.72%503K$11.0M−3,808 (−0.8%)September 30, 2026
6JPMorgan Small Cap Growth A0.72%500K$10.9M−71,788 (−12.5%)August 31, 2026
7JPMorgan Active Growth ETF0.59%412K$9.0M−196 (−0.0%)September 30, 2026
8abrdn Healthcare Investors0.59%412K$9.0M—September 30, 2026
9Fidelity Select Biotechnology0.56%389K$8.5M—August 31, 2026
10Schwab US Small-Cap ETF™0.53%365K$8.0M+243 (+0.1%)September 30, 2026
11RTW Biotech Opportunities Ord0.52%362K$7.9M−1.0M (−73.9%)December 31, 2025
12abrdn Life Sciences Investors0.52%362K$7.9M+163,371 (+82.4%)September 30, 2026
13PGIM Jennison Health Sciences Z0.49%337K$7.3M—September 30, 2026
14Fidelity Extended Market Index0.48%331K$7.2M−3,450 (−1.0%)August 31, 2026
15Biotech Growth Ord0.40%276K$6.0M—June 30, 2026
16JNL/JPMorgan MidCap Growth A0.38%262K$5.7M+106,994 (+69.0%)June 30, 2026
17abrdn World Healthcare0.37%260K$5.7M−240,907 (−48.1%)August 31, 2026
18Nomura Healthcare Fund Class I0.31%218K$4.7M—August 31, 2026
19Fidelity Contrafund0.31%215K$4.7M−85 (−0.0%)August 31, 2026
20JPM Thmtcs Gentc Thrps C2 dist USD0.30%207K$4.5M−659 (−0.3%)September 30, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

QURE insider transactions

latest 20
uniQure N.V. insider transactions
DateNameTransactionPriceSharesValue
2026-03-04Jeannette PottsSell$9.063,412$30,913
2026-03-04Matthew C KapustaSell$9.0614,581$132,104
2026-03-04Walid Abi-SaabSell$9.06808$7,320
2026-03-04Christian KlemtSell$9.0612,000$108,720
2026-02-25Christian KlemtSell$23.866,217$148,338
2026-02-25Matthew C KapustaSell$23.8612,378$295,339
2026-01-12Robert GutSell$24.6225,613$630,592
2026-01-09Jack KayeSell$27.286,390$174,319
2025-11-06Robert GutSell$27.2631,434$856,891
2025-11-04Jack KayeSell$30.3438,810$1.2M
2025-09-26Christian KlemtSell$55.0015,000$825,000
2025-09-24Christian KlemtSell$40.043,000$120,120
2025-09-24Matthew C KapustaSell$41.46226,316$9.4M
2025-06-27Walid Abi-SaabSell$13.921,466$20,407
2025-06-20David D MeekSell$14.452,112$30,518
2025-06-20Jack KayeSell$14.452,112$30,518
2025-06-20Jeremy P SpringhornSell$14.452,112$30,518
2025-06-20Leonard E PostSell$14.452,112$30,518
2025-06-20Madhavan BalachandranSell$14.452,112$30,518
2025-06-20Rachelle Suzanne JacquesSell$14.452,112$30,518

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

QURE shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns QURE

Institutional investors own 98.1% of uniQure's shares and insiders 1.26%. The largest holder is venBio Select Advisor LLC with 9.70% of the shares (6.7M), as of June 30, 2026. Among the top 20 institutions, 15 added shares and 5 reduced their stake in the latest filings. Short interest is 12.73% of the float, or 2.90 days of average trading volume. The share count rose 235.9% since 2014.

Related: QURE analyst forecast, QURE key metrics. See the QURE stock overview for the latest quote and news.

QURE ownership FAQ

Who owns the most uniQure stock?

The largest shareholders of uniQure are venBio Select Advisor LLC (9.70%), JPMorgan Chase & Co (7.02%), RTW INVESTMENTS, LLC (5.68%), State Street Corp (4.19%), Aberdeen Group PLC (4.11%).

What percentage of uniQure is owned by institutions?

Institutions hold 98.1% of uniQure's shares outstanding; insiders hold 1.26%.

Which funds own uniQure?

The largest fund holders of uniQure are State Street® SPDR® S&P® Biotech ETF (2.95%), JPMorgan Growth Advantage A (2.52%), JPMorgan Mid Cap Growth I (1.77%), Worldwide Healthcare Ord (1.08%), iShares Biotechnology ETF (0.72%).

What is uniQure's short interest?

8.7M shares of uniQure were sold short, 12.73% of the float; at the average daily volume it would take 2.90 days to cover.

Are insiders buying or selling uniQure?

Of the latest 20 reported insider transactions in uniQure (since June 20, 2025), 0 were purchases and 20 were sales.

How many shares of uniQure are outstanding?

uniQure has 69.4M shares outstanding, of which 57.5M are in the public float.

Biotechnology: ownership