Q32 Bio Inc. (QTTB) Ownership

NASDAQ: QTTBTop holders, insider trades and short interest.

QTTB ownership summary

as of October 18, 2026
Institutions
87.7%
of shares outstanding
Insiders
2.08%
of shares outstanding
Shares outstanding
29.8M
Float
12.7M
shares available to trade
Short interest
22.29%
4.7M shares short
Days to cover
5.14
short interest up 23.8% vs prior month
  • Institutions 87.73%
  • Insiders 2.08%
  • Other investors 10.20%

QTTB top institutional holders

20 largest
Q32 Bio Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Orbimed Advisors LLC17.43%4.1M$31.0M+1.9M (+83.2%)June 30, 2026
2Boxer Capital Management, LLC13.30%3.1M$23.7M+3.1M (0.0%)June 30, 2026
3Atlas Venture Life Science Advisors, LLC11.47%2.7M$20.4M+625,000 (+29.9%)June 30, 2026
4Bvf Inc9.92%2.4M$17.7M+2.4M (0.0%)June 30, 2026
5RA Capital Management, LLC9.85%2.3M$17.5M+2.3M (0.0%)June 30, 2026
6Point72 Asset Management, L.P.4.95%1.2M$8.8M+1.2M (0.0%)June 30, 2026
7Opaleye Management Inc3.93%931K$7.0M−325,228 (−25.9%)June 30, 2026
8Logos Global Management LP3.38%800K$6.0M+800,000 (0.0%)June 30, 2026
9SummitTX Capital, L.P3.10%734K$5.5M+733,774 (0.0%)June 30, 2026
10Vanguard Capital Management, LLC2.19%519K$3.9M+212,402 (+69.3%)June 30, 2026
11Ikarian Capital, LLC1.82%430K$3.2M+430,000 (0.0%)June 30, 2026
12Woodline Partners LP1.21%286K$2.2M+286,212 (0.0%)June 30, 2026
13American Century Companies Inc1.15%273K$2.1M+253,982 (+1,353.1%)June 30, 2026
14Sanofi1.03%244K$1.8M—June 30, 2026
15Acadian Asset Management LLC0.92%218K$1.6M+45,648 (+26.4%)June 30, 2026
16Renaissance Technologies Corp0.76%180K$1.4M−27,315 (−13.2%)June 30, 2026
17Jane Street Group LLC0.69%163K$1.2M+97,148 (+148.1%)June 30, 2026
18MONIMUS CAPITAL MANAGEMENT, LP0.56%132K$992,911−2,274 (−1.7%)June 30, 2026
19BOOTHBAY FUND MANAGEMENT, LLC0.55%130K$980,811+130,427 (0.0%)June 30, 2026
20Geode Capital Management, LLC0.52%123K$922,629+4,538 (+3.8%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 16 holders added 14.5M shares and 3 cut 355K.

QTTB top mutual fund and ETF holders

20 largest
Q32 Bio Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Vanguard MStar Total Stk Mkt Idx Invest3.19%755K$5.7M—August 31, 2026
2Avantis US Small Cap Value ETF2.24%530K$4.0M—September 30, 2026
3JPMorgan Small Cap Growth A2.08%494K$3.7M−14,555 (−2.9%)August 31, 2026
4Columbia Small Cap Growth Inst1.46%346K$2.6M+345,928 (0.0%)August 31, 2026
5MEDICAL BioHealth EUR Acc0.76%181K$1.4M+38 (+0.0%)August 31, 2026
6JPMorgan Small Cap Blend A0.67%158K$1.2M−2,907 (−1.8%)August 31, 2026
7First Trust Dow Jones Sel MicroCap ETF0.38%89K$670,288—September 30, 2026
8Multi-Manager Small Cap Eq Strat Inst0.28%66K$499,486−13,863 (−17.3%)August 31, 2026
9JPM US Small Cap Growth A dist USD0.23%55K$417,104−336 (−0.6%)August 31, 2026
10Fidelity Extended Market Index0.21%51K$381,580−273 (−0.5%)August 31, 2026
11Avantis® U.S. Small Cap Value Instl0.21%51K$380,723+34,794 (+219.7%)August 31, 2026
12Truvalue Glb Phrmctl Blgcl Eq (QDII) A0.20%47K$355,320+47,250 (0.0%)June 30, 2026
13Dimensional US Small Cap ETF0.17%41K$307,545—September 30, 2026
14JPM US Small Cap Growth C Acc0.16%37K$281,413−4 (−0.0%)August 31, 2026
15Bridgeway Ultra-Small Company0.15%35K$260,290+22,000 (+174.4%)June 30, 2026
16iShares Micro-Cap ETF0.13%30K$229,082−210 (−0.7%)September 30, 2026
17JHVIT Health Sciences I0.12%29K$218,817—August 31, 2026
18Avantis US Small Cap Equity ETF0.11%27K$204,476+170 (+0.6%)September 30, 2026
19JPMorgan American Ord0.11%25K$188,948+25,126 (0.0%)July 31, 2026
20Fidelity Nasdaq Composite Index0.10%24K$178,931+9,708 (+68.9%)August 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

QTTB insider transactions

latest 8
Q32 Bio Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-02-25Jodie Pope MorrisonSell$4.519,896$44,631
2026-02-25Lee KalowskiSell$4.513,995$18,017
2026-02-25Shelia M VioletteSell$4.512,815$12,696
2025-12-02Jodie Pope MorrisonSell$3.4622,506$77,871
2025-12-02Lee KalowskiSell$3.469,072$31,389
2025-08-26Jodie Pope MorrisonSell$1.8010,494$18,889
2025-08-26Lee KalowskiSell$1.804,240$7,632
2025-08-26Shelia M VioletteSell$1.802,990$5,382

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

QTTB shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns QTTB

Institutional investors own 87.7% of Q32 Bio's shares and insiders 2.08%. The largest holder is Orbimed Advisors LLC with 17.43% of the shares (4.1M), as of June 30, 2026. Among the top 20 institutions, 16 added shares and 3 reduced their stake in the latest filings. Short interest is 22.29% of the float, or 5.14 days of average trading volume. The share count rose 535.0% since 2017.

Related: QTTB analyst forecast, QTTB key metrics. See the QTTB stock overview for the latest quote and news.

QTTB ownership FAQ

Who owns the most Q32 Bio stock?

The largest shareholders of Q32 Bio are Orbimed Advisors LLC (17.43%), Boxer Capital Management, LLC (13.30%), Atlas Venture Life Science Advisors, LLC (11.47%), Bvf Inc (9.92%), RA Capital Management, LLC (9.85%).

What percentage of Q32 Bio is owned by institutions?

Institutions hold 87.7% of Q32 Bio's shares outstanding; insiders hold 2.08%.

Which funds own Q32 Bio?

The largest fund holders of Q32 Bio are Vanguard MStar Total Stk Mkt Idx Invest (3.19%), Avantis US Small Cap Value ETF (2.24%), JPMorgan Small Cap Growth A (2.08%), Columbia Small Cap Growth Inst (1.46%), MEDICAL BioHealth EUR Acc (0.76%).

What is Q32 Bio's short interest?

4.7M shares of Q32 Bio were sold short, 22.29% of the float; at the average daily volume it would take 5.14 days to cover.

Are insiders buying or selling Q32 Bio?

Of the latest 8 reported insider transactions in Q32 Bio (since August 26, 2025), 0 were purchases and 8 were sales.

How many shares of Q32 Bio are outstanding?

Q32 Bio has 29.8M shares outstanding, of which 12.7M are in the public float.

Biotechnology: ownership