Halozyme Therapeutics, Inc. (HALO) Key Metrics

NASDAQ: HALOValuation, returns, debt and efficiency ratios over 10 years.

HALO valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$13.83B
Enterprise value
$14.68B
P/E (TTM)
35.6
10-yr median 26.3
Forward P/E
11.5
PEG ratio
—
Price / sales
8.3
10-yr median 10.5
Price / book
88.9
10-yr median 30.0
EV / EBITDA
15.9
10-yr median 21.7
Dividend yield
—
Beta
0.88

HALO key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

HALO valuation Price multiples at each fiscal year-end price.

P/E ratio+88.9%
26.3
2025 · hover or tap a bar for each year
2017: 44.72020: 46.82021: 14.7 (−68.7%)2022: 39.6 (+170.0%)2023: 17.6 (−55.5%)2024: 13.9 (−20.9%)2025: 26.3 (+88.9%)
20162025
Price / sales−2.0%
6.0
2025 · hover or tap a bar for each year
2016: 8.6 (−47.0%)2017: 8.9 (+3.3%)2018: 13.8 (+55.5%)2019: 13.1 (−5.6%)2020: 22.6 (+72.9%)2021: 13.3 (−41.0%)2022: 12.1 (−9.0%)2023: 6.0 (−50.7%)2024: 6.1 (+1.9%)2025: 6.0 (−2.0%)
20162025
Price / book+904.4%
170.8
2025 · hover or tap a bar for each year
2017: 13.52018: 8.4 (−37.6%)2019: 27.9 (+230.4%)2020: 40.0 (+43.4%)2021: 30.0 (−25.1%)2022: 47.1 (+57.2%)2023: 59.2 (+25.6%)2024: 17.0 (−71.3%)2025: 170.8 (+904.4%)
20162025
EV / EBITDA+66.9%
18.0
2025 · hover or tap a bar for each year
2017: 30.72020: 41.12021: 21.7 (−47.4%)2022: 29.0 (+33.9%)2023: 13.5 (−53.3%)2024: 10.8 (−20.2%)2025: 18.0 (+66.9%)
20162025
Price / free cash flow−2.1%
12.9
2025 · hover or tap a bar for each year
2017: 21.22020: 114.12021: 19.8 (−82.6%)2022: 34.0 (+71.6%)2023: 13.3 (−60.9%)2024: 13.2 (−0.6%)2025: 12.9 (−2.1%)
20162025
Free cash flow yield+0.2 pts
7.7%
2025 · hover or tap a bar for each year
2016: −4.2% (−2.4 pts)2017: 4.7% (+8.9 pts)2018: −2.6% (−7.3 pts)2019: −3.5% (−0.9 pts)2020: 0.9% (+4.4 pts)2021: 5.0% (+4.2 pts)2022: 2.9% (−2.1 pts)2023: 7.5% (+4.6 pts)2024: 7.6% (0.0 pts)2025: 7.7% (+0.2 pts)
20162025

HALO valuation history

Fiscal year-endToday10-year median

HALO returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

HALO debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

HALO cash returned to shareholders

DividendsBuybacksFree cash flow

HALO price vs earnings per share

Share price at year-endEPS (right axis)

HALO key metrics

2016–2025
Halozyme Therapeutics, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$8.34B$6.19B$4.96B$8.00B$5.90B$6.04B$2.56B$2.10B$2.82B$1.26B
Enterprise value$10.34B$7.10B$6.12B$9.14B$6.04B$6.07B$2.54B$1.87B$2.55B$1.28B
P/E ratio26.313.917.639.614.746.8——44.7—
Price / sales6.06.16.012.113.322.613.113.88.98.6
Price / book170.817.059.247.130.040.027.98.413.5—
Price / free cash flow12.913.213.334.019.8114.1——21.2—
Price / operating cash flow12.812.912.833.319.7109.0——21.0—
EV / sales7.47.07.413.913.622.713.012.38.18.7
EV / EBITDA18.010.813.529.021.741.1——30.7—
EV / free cash flow16.015.216.438.920.3114.7——19.2—
Earnings yield3.8%7.2%5.7%2.5%6.8%2.1%−2.8%−3.8%2.2%−8.1%
Free cash flow yield7.7%7.6%7.5%2.9%5.0%0.9%−3.5%−2.6%4.7%−4.2%
Dividend yield——0.3%—0.2%1.0%0.6%—0.0%0.0%
Shareholder yield (dividends + buybacks)4.1%4.0%8.4%2.5%6.1%3.5%8.4%0.0%0.0%0.0%
Share price at fiscal year-end$67.30$47.81$36.96$56.90$40.21$42.71$17.73$14.63$20.26$9.88
Per share
Revenue per share$11.27$7.84$6.18$4.69$3.02$1.89$1.36$1.06$2.28$1.15
Earnings per share$2.56$3.43$2.10$1.44$2.74$0.91−$0.50−$0.56$0.45−$0.81
Operating cash flow per share$5.26$3.70$2.90$1.71$2.04$0.39−$0.59−$0.34$0.96−$0.39
Free cash flow per share$5.20$3.62$2.78$1.67$2.03$0.37−$0.62−$0.38$0.95−$0.42
Cash per share$1.15$4.61$2.50$2.58$5.05$2.60$2.92$2.47$3.37$1.60
Book value per share$0.39$2.81$0.62$1.21$1.34$1.07$0.64$1.73$1.50−$0.25
Tangible book value per share−$12.21−$3.51−$6.01−$5.59$1.34$1.07$0.64$1.73$1.50−$0.25
Dividends per share——$0.10—$0.09$0.45$0.10—$0.00$0.00
Capex per share$0.06$0.08$0.11$0.03$0.01$0.02$0.03$0.03$0.01$0.02
Debt per share$17.29$11.63$11.17$10.71$5.97$2.81$2.79$0.88$1.46$1.69
Shares outstanding123.9M129.4M134.2M140.6M146.8M141.5M144.3M143.6M139.1M128.0M
Change in shares outstanding−4.3%−3.6%−4.6%−4.2%+3.8%−2.0%+0.5%+3.3%+8.7%+1.0%
Returns & profitability
Return on equity (ROE)153.6%198.4%222.1%110.2%231.4%106.3%−42.4%−35.1%71.6%—
Return on invested capital (ROIC)32.8%34.9%21.3%26.4%107.6%113.7%−113.8%———
Return on assets (ROA)13.8%23.4%15.8%13.7%47.8%22.5%−14.4%−16.7%16.1%−46.5%
Return on tangible assets32.9%35.7%33.4%22.8%36.5%22.3%−12.8%−18.2%12.1%−39.4%
Free cash flow margin46.2%46.1%45.0%35.6%67.2%19.8%−45.6%−35.7%41.9%−36.5%
Income quality (OCF / net income)2.061.081.381.190.740.43——2.13—
Financial health
Total debt$2.14B$1.51B$1.50B$1.51B$876.7M$397.2M$402.6M$126.4M$202.4M$216.6M
Cash & short-term investments$142.8M$596.1M$336.0M$362.8M$740.9M$368.0M$421.3M$354.5M$469.2M$205.0M
Net debt$2.00B$909.7M$1.16B$1.14B$135.8M$29.2M−$18.7M−$228.1M−$266.9M$11.6M
Debt / equity43.894.1417.898.874.452.634.390.510.97—
Debt / assets0.850.730.860.820.790.680.710.290.390.83
Net debt / EBITDA3.491.392.573.620.490.20——−3.21—
Current ratio4.667.806.645.657.911.326.352.863.894.70
Quick ratio3.666.785.504.887.451.176.002.713.854.43
Interest coverage44.330.518.015.836.77.1-5.8-3.83.7-4.2
Working capital$648.1M$946.2M$633.9M$608.2M$809.1M$133.4M$457.8M$278.5M$379.0M$201.9M
Invested capital$2.05B$1.27B$1.25B$1.31B$332.7M$180.3M$73.1M$20.7M−$58.5M−$20.8M
Tangible asset value−$1.51B−$454.8M−$805.9M−$785.9M$197.0M$151.0M$91.8M$248.9M$208.4M−$32.5M
Net current asset value−$1.65B−$614.3M−$903.0M−$932.7M$18.8M$125.9M$69.3M$236.5M$198.8M−$37.5M
Graham number$4.76$14.73$5.43$6.25$9.10$4.68——$3.91—
Graham net-net per share−$15.45−$6.19−$8.00−$7.72−$0.49$0.30$0.04$1.37$1.27−$0.55
Capital allocation
Dividends paid——$13.5M—$12.5M$63.4M$14.2M—$0$0
Share buybacks (net)$342.4M$250.0M$402.4M$200.0M$350.1M$150.1M$200.0M$0$0$0
Dividend payout ratio——4.8%—3.1%49.1%——0.0%—
Dividends + buybacks / free cash flow53.1%53.4%111.4%85.0%121.7%403.2%——0.0%—
Capex / revenue0.5%1.1%1.8%0.7%0.3%0.9%2.1%3.1%0.4%2.1%
Capex / operating cash flow1.1%2.2%3.9%2.0%0.5%4.5%——1.0%—
Capex / depreciation0.080.130.180.100.490.760.991.950.621.30
Stock-based compensation / revenue3.7%4.3%4.4%3.7%4.7%6.4%17.7%23.5%9.7%17.4%
R&D / revenue5.8%7.8%9.2%10.1%8.0%12.8%71.8%98.9%47.6%102.8%
SG&A / revenue14.8%15.2%18.0%21.7%11.4%17.1%39.4%40.0%17.0%31.3%
Efficiency
Days sales outstanding98.097.5102.489.077.7107.283.362.721.859.8
Days of inventory on hand253.9308.5216.1201.8257.0379.2208.3500.0115.8132.5
Days payables outstanding24.825.328.025.27.835.242.1216.567.544.4
Cash conversion cycle (days)327.1380.8290.5265.6326.9451.2249.5346.170.1148.0
Receivables turnover3.733.743.564.104.703.414.385.8316.756.10
Payables turnover14.6914.4513.0414.4946.9410.378.661.695.418.22
Inventory turnover1.441.181.691.811.420.961.750.733.152.75
Asset turnover0.610.530.460.450.530.470.390.320.810.66
Average receivables$374.9M$271.3M$232.6M$161.0M$94.4M$78.6M$44.7M$26.1M$18.9M$24.0M
Average payables$15.6M$11.0M$14.8M$9.6M$1.7M$4.2M$5.3M$6.0M$5.8M$4.0M
Average inventory$159.2M$134.7M$113.9M$77.0M$57.3M$45.1M$26.0M$13.9M$9.9M$12.1M
Intangibles / total assets61.8%39.7%51.3%51.9%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from HALO's annual financial statements (latest annual report filed February 17, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

HALO valuation and financial ratios

At the end of fiscal 2025 (December 31, 2025), Halozyme Therapeutics traded at 26.3 times earnings, against a 10-year median of 26.3. Based on the latest twelve months, the trailing P/E is 35.6 and the forward P/E is 11.5. Halozyme Therapeutics earned a return on equity of 153.6% and a return on invested capital of 32.8% in fiscal 2025. It ended the year with $2.1 billion of debt and $142.8 million in cash and short-term investments, net debt of $2.0 billion. It returned $342.4 million to shareholders: $0 in dividends and $342.4 million in share buybacks, 53% of free cash flow. The share count fell 3.2% from 128.0M to 123.9M over 9 years.

See the HALO income statement, the HALO chart for price history, or the HALO stock overview for the latest quote and news.

HALO key metrics FAQ

What is Halozyme Therapeutics's P/E ratio?

Halozyme Therapeutics's trailing P/E ratio is 35.6 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 11.5. At the end of fiscal 2025 it was 26.3, compared with a 10-year median of 26.3.

What is Halozyme Therapeutics's EV/EBITDA?

Halozyme Therapeutics's enterprise value was 18.0 times EBITDA at the end of fiscal 2025 (enterprise value $10.3 billion, EBITDA $573.1 million); the current EV/EBITDA is 15.9.

What is Halozyme Therapeutics's return on equity?

Halozyme Therapeutics's return on equity (ROE) was 153.6% in fiscal 2025: net income of $316.9 million on average shareholders' equity of $206.3 million. ROE is high partly because years of buybacks have reduced equity on the balance sheet.

What is Halozyme Therapeutics's ROIC?

Halozyme Therapeutics's return on invested capital was 32.8% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Halozyme Therapeutics have?

Halozyme Therapeutics had total debt of $2.1 billion at the end of fiscal 2025, a debt-to-equity ratio of 43.89 and $2.0 billion of net debt (3.49 times EBITDA).

Does Halozyme Therapeutics buy back its shares?

Yes. Halozyme Therapeutics spent $342.4 million on net share repurchases in fiscal 2025 Shares outstanding changed −4.3% over the year, to 123.9M..

What is Halozyme Therapeutics's free cash flow yield?

Halozyme Therapeutics generated $644.6 million of free cash flow in fiscal 2025, a free cash flow yield of 7.7% on its market value at year-end ($8.3 billion).

What is Halozyme Therapeutics's current ratio?

Halozyme Therapeutics's current ratio was 4.66 at the end of fiscal 2025: current assets were 4.66 times current liabilities.

Biotechnology key metrics