Horizon Kinetics Medical ETF (MEDX) Performance

NASDAQ: MEDXTotal returns, calendar years, drawdowns and risk since 2023.

MEDX total return

Distributions reinvested · as of Oct 23, 2026
YTD
+10.0%
since Dec 31, 2025
1 year
+17.1%
total return
3 years
+12.2%
a year
Since first price
+6.8%
a year since 2023

MEDX trailing returns vs SPY, QQQ, AGG

MEDX trailing returns
PeriodMEDX total returnPrice onlyS&P 500 (SPY)Nasdaq-100 (QQQ)U.S. bonds (AGG)
1 month+3.2%+3.2%−1.0%−5.0%+0.9%
3 months+3.3%+3.3%+3.2%+1.9%−0.4%
6 months+11.4%+11.4%+7.8%+8.4%−1.5%
YTD+10.0%+10.0%+12.3%+15.1%−1.0%
1 year+17.1%+15.7%+14.4%+15.9%−1.1%
3 years+41.4%+12.2%/yr+29.5%+87.4%+23.3%/yr+101.4%+26.3%/yr+16.6%+5.2%/yr
Since inceptionJan 31, 2023+27.7%+6.8%/yr+16.9%———

Total return from adjusted closes (distributions reinvested, before tax). Periods of 3 years or more are also shown annualized. Price only excludes distributions.

Growth of $10,000: MEDX vs SPY

MEDXS&P 500 (SPY)

From Jan 31, 2023: MEDX grew to $12,770, SPY to $19,602.

Year-end values with distributions reinvested, no taxes or trading costs. Start: first common trading day of both funds.

MEDX returns by calendar year

MEDXSPY

1 of 2 full years positive. Best 2025 (+28.6%), worst 2024 (−4.7%). 2026 is year to date.

MEDX annual returns table

MEDX calendar-year returns
YearMEDXLargest dropSPYQQQAGG
2026YTD+10.0%−10.5%+12.3%+15.1%−1.0%
2025+28.6%−17.1%+17.7%+20.8%+7.2%
2024−4.7%−16.6%+24.9%+25.6%+1.3%

Largest drop = deepest fall from a high within that calendar year.

Calendar-year return vs largest drop within the year

Calendar-year returnLargest drop within the year

Most years include a sizable fall at some point even when the year ends higher.

MEDX largest drawdowns

Now 3.5% below the high
MEDX largest drawdowns
PeakDeclineBottomRecoveredFallUnderwater
Aug 30, 2024−23.1%Apr 10, 2025Oct 1, 20257 months1.1 years
May 10, 2023−15.5%Oct 27, 2023Feb 27, 20246 months10 months
Feb 24, 2026−10.5%Apr 29, 2026Jun 25, 20262 months4 months
Feb 28, 2024−10.3%Apr 19, 2024Jul 11, 202451 days4 months

Declines from a closing high (distributions reinvested) of 10% or more. Underwater = time from the peak until the old high was regained.

MEDX risk statistics

MEDX risk statistics
Statistic3 yearsSince 2023
Annualized return+9.6%+5.9%
Volatility (annualized)15.4%14.6%
Sharpe ratio0.390.16
Sortino ratio0.580.23
Best month+8.6%+8.6%
Worst month−6.5%−6.5%
Best 12 months+39.4%+39.4%
Worst 12 months−9.0%−9.0%
Positive months58%57%
Beta vs S&P 5000.45—
Correlation with S&P 5000.37—

From monthly total returns. Sharpe and Sortino use 1–3 month T-bills (BIL) as the risk-free rate, so they need history from 2007 on.

MEDX rolling returns

MEDX rolling returns
Holding periodPeriodsWorstMedianBestPositive
1-year34−9.0%+7.5%+39.4%65%
3-year (a year)10+5.4%+8.8%+13.4%100%

Every holding period starting at a month-end since 2023. Returns for 3 years and longer are annualized.

MEDX performance overview

Horizon Kinetics Medical ETF (MEDX) returned +17.1% over the past year, with distributions reinvested. Since its first recorded price in 2023 it has returned +6.8% a year, turning $10,000 into about $12,770. Over the same year S&P 500 (SPY) returned +14.4%.

The deepest decline was −23.1%, from Aug 30, 2024 to Apr 10, 2025, and it took 6 months to get back to the old high. Volatility has been 14.6% a year.

Related: MEDX chart, MEDX holdings, MEDX dividends, MEDX valuation. See the MEDX overview for the latest quote and fund facts.

MEDX performance FAQ

What is the MEDX return over the past year?

MEDX returned +17.1% over the 12 months to October 23, 2026, including reinvested distributions. On price alone it rose 15.7%.

How much would $10,000 invested in MEDX be worth?

$10,000 invested in MEDX at its first recorded close on January 31, 2023 would be worth about $12,770 on October 23, 2026 with distributions reinvested.

What was the worst year for MEDX?

The worst calendar year was 2024, with a total return of −4.7%. The best was 2025 at +28.6%.

What is the biggest drawdown of MEDX?

The largest peak-to-trough decline was −23.1% between August 30, 2024 and April 10, 2025. It recovered to the old high on October 1, 2025, 6 months after the bottom.

How volatile is MEDX?

Over the past 3 years MEDX had an annualized volatility of 15.4% and a Sharpe ratio of 0.39 (excess return over 1–3 month T-bills per unit of risk).