Global X Genomics & Biotechnology ETF (GNOM) Performance
GNOM total return
Distributions reinvested · as of Oct 23, 2026- YTD
- +44.4% since Dec 31, 2025
- 1 year
- +53.3% total return
- 5 years
- −5.1% a year
- Since first price
- +1.1% a year since 2019
GNOM trailing returns vs SPY, QQQ, AGG
| Period | GNOM total return | Price only | S&P 500 (SPY) | Nasdaq-100 (QQQ) | U.S. bonds (AGG) |
|---|---|---|---|---|---|
| 1 month | −3.2% | −3.2% | −1.0% | −5.0% | +0.9% |
| 3 months | +19.5% | +19.5% | +3.2% | +1.9% | −0.4% |
| 6 months | +42.2% | +42.1% | +7.8% | +8.4% | −1.5% |
| YTD | +44.4% | +44.3% | +12.3% | +15.1% | −1.0% |
| 1 year | +53.3% | +51.2% | +14.4% | +15.9% | −1.1% |
| 3 years | +81.6%+22.0%/yr | +79.0% | +87.4%+23.3%/yr | +101.4%+26.3%/yr | +16.6%+5.2%/yr |
| 5 years | −23.1%−5.1%/yr | −24.3% | +79.3%+12.4%/yr | +94.0%+14.2%/yr | −0.8%−0.2%/yr |
| Since inceptionApr 10, 2019 | +8.3%+1.1%/yr | +6.7% | — | — | — |
Total return from adjusted closes (distributions reinvested, before tax). Periods of 3 years or more are also shown annualized. Price only excludes distributions.
Growth of $10,000: GNOM vs SPY
From Apr 10, 2019: GNOM grew to $10,833, SPY to $29,412.
Year-end values with distributions reinvested, no taxes or trading costs. Start: first common trading day of both funds.
GNOM returns by calendar year
2 of 6 full years positive. Best 2020 (+51.4%), worst 2022 (−36.3%). 2026 is year to date.
GNOM annual returns table
| Year | GNOM | Largest drop | SPY | QQQ | AGG |
|---|---|---|---|---|---|
| 2026YTD | +44.4% | −18.2% | +12.3% | +15.1% | −1.0% |
| 2025 | +18.7% | −32.3% | +17.7% | +20.8% | +7.2% |
| 2024 | −16.0% | −21.7% | +24.9% | +25.6% | +1.3% |
| 2023 | −8.6% | −38.2% | +26.2% | +54.9% | +5.7% |
| 2022 | −36.3% | −46.6% | −18.2% | −32.6% | −13.0% |
| 2021 | −15.9% | −30.4% | +28.7% | +27.4% | −1.8% |
| 2020 | +51.4% | −35.3% | +18.3% | +48.6% | +7.5% |
Largest drop = deepest fall from a high within that calendar year.
Calendar-year return vs largest drop within the year
Most years include a sizable fall at some point even when the year ends higher.
GNOM largest drawdowns
Now 40.3% below the high| Peak | Decline | Bottom | Recovered | Fall | Underwater |
|---|---|---|---|---|---|
| Feb 8, 2021 | −75.0% | Apr 8, 2025 | not yet | 4.2 years | 5.7 years so far |
| Dec 24, 2019 | −35.4% | Mar 18, 2020 | May 18, 2020 | 3 months | 5 months |
| Apr 10, 2019 | −21.6% | Oct 2, 2019 | Nov 27, 2019 | 6 months | 8 months |
| Jul 20, 2020 | −14.4% | Sep 8, 2020 | Oct 7, 2020 | 50 days | 3 months |
Declines from a closing high (distributions reinvested) of 10% or more. Underwater = time from the peak until the old high was regained.
GNOM risk statistics
| Statistic | 3 years | 5 years | Since 2019 |
|---|---|---|---|
| Annualized return | +20.7% | −4.2% | +3.0% |
| Volatility (annualized) | 31.2% | 29.8% | 30.3% |
| Sharpe ratio | 0.62 | -0.12 | 0.16 |
| Sortino ratio | 1.02 | -0.17 | 0.25 |
| Best month | +18.9% | +18.9% | +18.9% |
| Worst month | −13.9% | −18.7% | −18.7% |
| Best 12 months | +84.0% | +84.0% | +84.0% |
| Worst 12 months | −30.1% | −43.3% | −50.9% |
| Positive months | 58% | 45% | 48% |
| Beta vs S&P 500 | 1.44 | 1.17 | — |
| Correlation with S&P 500 | 0.57 | 0.61 | — |
From monthly total returns. Sharpe and Sortino use 1–3 month T-bills (BIL) as the risk-free rate, so they need history from 2007 on.
GNOM rolling returns
| Holding period | Periods | Worst | Median | Best | Positive |
|---|---|---|---|---|---|
| 1-year | 79 | −50.9% | −3.8% | +84.0% | 47% |
| 3-year (a year) | 55 | −25.1% | −9.5% | +23.4% | 15% |
| 5-year (a year) | 31 | −14.0% | −9.0% | −2.1% | 0% |
Every holding period starting at a month-end since 2019. Returns for 3 years and longer are annualized.
GNOM performance overview
Global X Genomics & Biotechnology ETF (GNOM) returned +53.3% over the past year and −5.1% a year over five years, with distributions reinvested. Since its first recorded price in 2019 it has returned +1.1% a year, turning $10,000 into about $10,833. Over the same year S&P 500 (SPY) returned +14.4%.
The deepest decline was −75.0%, from Feb 8, 2021 to Apr 8, 2025; the fund has not yet regained that high. GNOM finished 2 of its 6 full calendar years with a gain; the best year was 2020 (+51.4%) and the worst 2022 (−36.3%). Volatility has been 30.3% a year.
Related: GNOM chart, GNOM holdings, GNOM dividends. See the GNOM overview for the latest quote and fund facts.
GNOM performance FAQ
What is the GNOM return over the past year?
GNOM returned +53.3% over the 12 months to October 23, 2026, including reinvested distributions. On price alone it rose 51.2%.
What is the average annual return of GNOM?
GNOM has returned −5.1% a year over 5 years, +1.1% a year since April 10, 2019 (total return, distributions reinvested).
How much would $10,000 invested in GNOM be worth?
$10,000 invested in GNOM at its first recorded close on April 10, 2019 would be worth about $10,833 on October 23, 2026 with distributions reinvested.
What was the worst year for GNOM?
The worst calendar year was 2022, with a total return of −36.3%. The best was 2020 at +51.4%.
What is the biggest drawdown of GNOM?
The largest peak-to-trough decline was −75.0% between February 8, 2021 and April 8, 2025. It has not yet recovered to that high; it is 40.3% below its peak.
How volatile is GNOM?
Over the past 3 years GNOM had an annualized volatility of 31.2% and a Sharpe ratio of 0.62 (excess return over 1–3 month T-bills per unit of risk).