Tema Oncology ETF (CANC) Performance
CANC total return
Distributions reinvested · as of Oct 23, 2026- YTD
- +18.9% since Dec 31, 2025
- 1 year
- +38.7% total return
- 3 years
- +25.1% a year
- Since first price
- +116.3% a year since 2023
CANC trailing returns vs SPY, QQQ, AGG
| Period | CANC total return | Price only | S&P 500 (SPY) | Nasdaq-100 (QQQ) | U.S. bonds (AGG) |
|---|---|---|---|---|---|
| 1 month | −0.5% | −0.5% | −1.0% | −5.0% | +0.9% |
| 3 months | −0.0% | −0.0% | +3.2% | +1.9% | −0.4% |
| 6 months | +7.6% | +7.6% | +7.8% | +8.4% | −1.5% |
| YTD | +18.9% | +18.9% | +12.3% | +15.1% | −1.0% |
| 1 year | +38.7% | +38.6% | +14.4% | +15.9% | −1.1% |
| 3 years | +95.6%+25.1%/yr | +89.1% | +87.4%+23.3%/yr | +101.4%+26.3%/yr | +16.6%+5.2%/yr |
| Since inceptionAug 14, 2023 | +1,073.3%+116.3%/yr | +1,034.3% | — | — | — |
Total return from adjusted closes (distributions reinvested, before tax). Periods of 3 years or more are also shown annualized. Price only excludes distributions.
Growth of $10,000: CANC vs SPY
From Aug 14, 2023: CANC grew to $117,333, SPY to $17,647.
Year-end values with distributions reinvested, no taxes or trading costs. Start: first common trading day of both funds.
CANC returns by calendar year
1 of 2 full years positive. Best 2025 (+42.9%), worst 2024 (−5.4%). 2026 is year to date.
CANC annual returns table
| Year | CANC | Largest drop | SPY | QQQ | AGG |
|---|---|---|---|---|---|
| 2026YTD | +18.9% | −13.2% | +12.3% | +15.1% | −1.0% |
| 2025 | +42.9% | −19.7% | +17.7% | +20.8% | +7.2% |
| 2024 | −5.4% | −16.8% | +24.9% | +25.6% | +1.3% |
Largest drop = deepest fall from a high within that calendar year.
Calendar-year return vs largest drop within the year
Most years include a sizable fall at some point even when the year ends higher.
CANC largest drawdowns
Now 8.7% below the high| Peak | Decline | Bottom | Recovered | Fall | Underwater |
|---|---|---|---|---|---|
| Jul 16, 2024 | −28.0% | Apr 8, 2025 | Oct 1, 2025 | 9 months | 1.2 years |
| Aug 14, 2023 | −16.5% | Aug 15, 2023 | Aug 16, 2023 | 1 days | 2 days |
| Sep 1, 2023 | −16.0% | Oct 27, 2023 | Dec 13, 2023 | 56 days | 3 months |
| Feb 27, 2024 | −13.3% | Apr 19, 2024 | Jul 12, 2024 | 52 days | 4 months |
| Aug 25, 2026 | −13.2% | Oct 13, 2026 | not yet | 49 days | 59 days so far |
Declines from a closing high (distributions reinvested) of 10% or more. Underwater = time from the peak until the old high was regained.
CANC risk statistics
| Statistic | 3 years | Since 2023 |
|---|---|---|
| Annualized return | +23.3% | +19.5% |
| Volatility (annualized) | 19.2% | 19.7% |
| Sharpe ratio | 0.96 | 0.78 |
| Sortino ratio | 1.84 | 1.41 |
| Best month | +15.4% | +15.4% |
| Worst month | −10.2% | −10.2% |
| Best 12 months | +66.9% | +66.9% |
| Worst 12 months | −12.0% | −12.0% |
| Positive months | 61% | 59% |
| Beta vs S&P 500 | 0.63 | — |
| Correlation with S&P 500 | 0.41 | — |
From monthly total returns. Sharpe and Sortino use 1–3 month T-bills (BIL) as the risk-free rate, so they need history from 2007 on.
CANC rolling returns
| Holding period | Periods | Worst | Median | Best | Positive |
|---|---|---|---|---|---|
| 1-year | 27 | −12.0% | +23.4% | +66.9% | 70% |
| 3-year (a year) | 3 | +21.4% | +23.3% | +24.7% | 100% |
Every holding period starting at a month-end since 2023. Returns for 3 years and longer are annualized.
CANC performance overview
Tema Oncology ETF (CANC) returned +38.7% over the past year, with distributions reinvested. Since its first recorded price in 2023 it has returned +116.3% a year, turning $10,000 into about $117,333. Over the same year S&P 500 (SPY) returned +14.4%.
The deepest decline was −28.0%, from Jul 16, 2024 to Apr 8, 2025, and it took 6 months to get back to the old high. Volatility has been 19.7% a year.
Related: CANC chart, CANC holdings, CANC dividends. See the CANC overview for the latest quote and fund facts.
CANC performance FAQ
What is the CANC return over the past year?
CANC returned +38.7% over the 12 months to October 23, 2026, including reinvested distributions. On price alone it rose 38.6%.
How much would $10,000 invested in CANC be worth?
$10,000 invested in CANC at its first recorded close on August 14, 2023 would be worth about $117,333 on October 23, 2026 with distributions reinvested.
What was the worst year for CANC?
The worst calendar year was 2024, with a total return of −5.4%. The best was 2025 at +42.9%.
What is the biggest drawdown of CANC?
The largest peak-to-trough decline was −28.0% between July 16, 2024 and April 8, 2025. It recovered to the old high on October 1, 2025, 6 months after the bottom.
How volatile is CANC?
Over the past 3 years CANC had an annualized volatility of 19.2% and a Sharpe ratio of 0.96 (excess return over 1–3 month T-bills per unit of risk).