Harmony Biosciences Holdings, Inc. (HRMY) Key Metrics

NASDAQ: HRMYValuation, returns, debt and efficiency ratios over 8 years.

HRMY valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$2.21B
Enterprise value
$1.84B
P/E (TTM)
12.2
10-yr median 15.1
Forward P/E
10.1
PEG ratio
—
Price / sales
2.3
10-yr median 5.5
Price / book
2.4
10-yr median 6.3
EV / EBITDA
6.6
10-yr median 8.1
Dividend yield
—
Beta
1.01

HRMY key metrics, 2018–2025

Fiscal year ended December 31, 2025 · U.S. dollars

HRMY valuation Price multiples at each fiscal year-end price.

P/E ratio+0.9%
13.8
2025 · hover or tap a bar for each year
2021: 73.02022: 18.6 (−74.6%)2023: 15.1 (−18.4%)2024: 13.7 (−9.6%)2025: 13.8 (+0.9%)
20182025
Price / sales−9.5%
2.5
2025 · hover or tap a bar for each year
2020: 13.12021: 8.3 (−36.9%)2022: 7.7 (−7.0%)2023: 3.4 (−56.4%)2024: 2.8 (−16.8%)2025: 2.5 (−9.5%)
20182025
Price / book−16.7%
2.5
2025 · hover or tap a bar for each year
2020: 21.52021: 13.5 (−37.1%)2022: 8.4 (−38.3%)2023: 4.2 (−50.0%)2024: 3.0 (−27.7%)2025: 2.5 (−16.7%)
20182025
EV / EBITDA−11.2%
6.5
2025 · hover or tap a bar for each year
2021: 30.92022: 22.0 (−28.7%)2023: 8.1 (−63.3%)2024: 7.3 (−9.6%)2025: 6.5 (−11.2%)
20182025
Price / free cash flow−30.8%
6.3
2025 · hover or tap a bar for each year
2021: 25.72022: 23.3 (−9.2%)2023: 8.9 (−61.8%)2024: 9.1 (+2.3%)2025: 6.3 (−30.8%)
20182025
Free cash flow yield+4.9 pts
15.9%
2025 · hover or tap a bar for each year
2020: −0.2%2021: 3.9% (+4.1 pts)2022: 4.3% (+0.4 pts)2023: 11.2% (+6.9 pts)2024: 11.0% (−0.3 pts)2025: 15.9% (+4.9 pts)
20182025

HRMY valuation history

Fiscal year-endToday8-year median

HRMY returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

HRMY debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

HRMY cash returned to shareholders

DividendsBuybacksFree cash flow

HRMY price vs earnings per share

Share price at year-endEPS (right axis)

HRMY key metrics

2018–2025
Harmony Biosciences Holdings, Inc. key metrics by fiscal year
20252024202320222021202020192018
Valuation
Market capitalization$2.19B$1.99B$1.95B$3.37B$2.52B$2.09B——
Enterprise value$1.65B$1.71B$1.79B$3.23B$2.49B$2.06B——
P/E ratio13.813.715.118.673.0———
Price / sales2.52.83.47.78.313.1——
Price / book2.53.04.28.413.521.5——
Price / free cash flow6.39.18.923.325.7———
Price / operating cash flow6.39.18.923.325.6———
EV / sales1.92.43.17.48.112.9——
EV / EBITDA6.57.38.122.030.9———
EV / free cash flow4.87.88.222.425.3———
Earnings yield7.2%7.3%6.6%5.4%1.4%−1.8%——
Free cash flow yield15.9%11.0%11.2%4.3%3.9%−0.2%——
Dividend yield——0.3%——9.6%——
Shareholder yield (dividends + buybacks)0.0%0.0%5.4%0.0%0.0%9.6%——
Share price at fiscal year-end$37.42$34.41$32.30$55.10$42.64$36.15——
Per share
Revenue per share$14.83$12.35$9.64$7.17$5.16$2.76$0.09$0.00
Earnings per share$2.71$2.51$2.13$2.97$0.58−$0.64−$2.39−$0.81
Operating cash flow per share$5.95$3.80$3.63$2.36$1.66−$0.05−$1.18−$0.79
Free cash flow per share$5.94$3.78$3.63$2.36$1.66−$0.09−$1.19−$0.82
Cash per share$13.24$8.07$5.85$5.29$3.96$3.95$0.38$1.70
Book value per share$14.86$11.39$7.74$6.59$3.15$1.68−$0.18$1.66
Tangible book value per share$13.34$9.43$5.46$3.96$0.72−$1.13−$1.32$1.66
Dividends per share——$0.08——$3.46$2.26—
Capex per share$0.01$0.02$0.01$0.00$0.01$0.03$0.00$0.03
Debt per share$4.09$3.13$3.21$3.14$3.31$3.36$1.54$6.58
Shares outstanding58.5M57.9M60.4M61.1M59.2M57.8M63.7M49.2M
Change in shares outstanding+1.2%−4.1%−1.2%+3.2%+2.3%−9.2%+29.3%—
Returns & profitability
Return on equity (ROE)20.8%25.8%29.6%61.6%24.4%−86.3%—−48.9%
Return on invested capital (ROIC)43.5%42.5%49.3%57.3%76.8%21.5%−60.0%−10.2%
Return on assets (ROA)14.0%16.1%17.4%32.8%8.0%−13.8%−155.1%−44.7%
Return on tangible assets13.4%16.4%19.1%35.4%11.9%−14.0%−440.3%−44.7%
Free cash flow margin40.1%30.6%37.6%33.0%32.2%−3.1%——
Income quality (OCF / net income)2.191.511.700.802.85———
Financial health
Total debt$239.6M$181.4M$193.6M$191.6M$195.7M$194.2M$97.9M$324.2M
Cash & short-term investments$775.3M$467.2M$353.5M$323.1M$234.3M$228.6M$24.5M$83.5M
Net debt−$535.8M−$285.8M−$159.9M−$131.5M−$38.6M−$34.4M$73.5M$240.7M
Debt / equity0.280.280.410.481.052.00—3.98
Debt / assets0.190.180.240.280.450.450.923.63
Net debt / EBITDA−2.10−1.22−0.72−0.90−0.48−22.72——
Current ratio3.603.312.755.075.291.951.5811.99
Quick ratio3.583.272.725.025.211.931.5311.99
Interest coverage14.210.98.16.43.60.6-24.0—
Working capital$654.9M$404.2M$287.3M$321.4M$230.7M$128.4M$11.6M$79.5M
Invested capital$334.5M$373.4M$307.1M$271.4M$147.9M$62.8M$61.9M$322.2M
Tangible asset value$780.8M$545.9M$329.9M$241.9M$42.6M−$65.2M−$83.8M$81.5M
Net current asset value$505.6M$239.2M$106.6M$129.3M$37.5M−$67.0M−$86.8M$78.9M
Graham number$30.11$25.38$19.27$20.99$6.44———
Graham net-net per share$7.67$3.34$1.11$1.56$0.27−$1.43−$1.41$1.54
Capital allocation
Dividends paid——$5.1M——$200.3M$143.8M—
Share buybacks (net)$0$0$100.0M$0$0$167,000$1.1M$3.2M
Dividend payout ratio——3.9%—————
Dividends + buybacks / free cash flow0.0%0.0%48.0%0.0%0.0%———
Capex / revenue0.0%0.2%0.1%0.0%0.1%1.3%2.5%—
Capex / operating cash flow0.1%0.5%0.1%0.1%0.3%———
Capex / depreciation0.010.050.010.010.020.200.057.29
Stock-based compensation / revenue5.2%6.0%5.4%6.1%5.3%2.9%165.3%—
R&D / revenue21.8%20.4%13.1%16.2%9.9%12.2%1,160.9%—
SG&A / revenue31.3%31.0%33.1%37.3%43.2%59.8%1,346.6%—
Efficiency
Days sales outstanding37.840.140.437.334.130.2129.5—
Days of inventory on hand11.614.614.519.127.132.3125.9—
Days payables outstanding28.936.632.410.511.758.7905.22,900.2
Cash conversion cycle (days)20.418.122.646.049.53.8-649.8—
Receivables turnover9.669.099.039.7810.7112.092.82—
Payables turnover12.629.9611.2734.8831.226.220.400.13
Inventory turnover31.6024.9725.1019.1313.4511.302.90—
Asset turnover0.760.790.780.790.710.600.060.00
Average receivables$89.9M$78.6M$64.4M$44.8M$28.5M$13.2M$2.1M$0
Average payables$15.7M$15.7M$10.8M$2.4M$1.8M$4.5M$3.9M$1.5M
Average inventory$6.3M$6.3M$4.8M$4.4M$4.1M$2.5M$544,000$0
Intangibles / total assets7.0%11.3%16.9%23.9%33.2%38.0%67.7%0.0%

Computed from HRMY's annual financial statements (latest annual report filed February 24, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

HRMY valuation and financial ratios

At the end of fiscal 2025 (December 31, 2025), Harmony Biosciences traded at 13.8 times earnings, against a 8-year median of 15.1. Based on the latest twelve months, the trailing P/E is 12.2 and the forward P/E is 10.1. Harmony Biosciences earned a return on equity of 20.8% and a return on invested capital of 43.5% in fiscal 2025. It ended the year with $239.6 million of debt and $775.3 million in cash and short-term investments, a net cash position of $535.8 million. The share count rose 18.9% from 49.2M to 58.5M over 7 years.

See the HRMY income statement, the HRMY chart for price history, or the HRMY stock overview for the latest quote and news.

HRMY key metrics FAQ

What is Harmony Biosciences's P/E ratio?

Harmony Biosciences's trailing P/E ratio is 12.2 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 10.1. At the end of fiscal 2025 it was 13.8, compared with a 8-year median of 15.1.

What is Harmony Biosciences's EV/EBITDA?

Harmony Biosciences's enterprise value was 6.5 times EBITDA at the end of fiscal 2025 (enterprise value $1.7 billion, EBITDA $255.0 million); the current EV/EBITDA is 6.6.

What is Harmony Biosciences's return on equity?

Harmony Biosciences's return on equity (ROE) was 20.8% in fiscal 2025: net income of $158.7 million on average shareholders' equity of $764.7 million.

What is Harmony Biosciences's ROIC?

Harmony Biosciences's return on invested capital was 43.5% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Harmony Biosciences have?

Harmony Biosciences had total debt of $239.6 million at the end of fiscal 2025, a debt-to-equity ratio of 0.28 and more cash than debt.

What is Harmony Biosciences's free cash flow yield?

Harmony Biosciences generated $347.9 million of free cash flow in fiscal 2025, a free cash flow yield of 15.9% on its market value at year-end ($2.2 billion).

What is Harmony Biosciences's current ratio?

Harmony Biosciences's current ratio was 3.60 at the end of fiscal 2025: current assets were 3.60 times current liabilities.

Biotechnology key metrics