4D Molecular Therapeutics, Inc. (FDMT) Key Metrics

NASDAQ: FDMTValuation, returns, debt and efficiency ratios over 9 years.

FDMT valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$670.7M
Enterprise value
$506.0M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
7.3
10-yr median 38.3
Price / book
2.0
10-yr median 2.2
EV / EBITDA
—
Dividend yield
—
Beta
2.74

FDMT key metrics, 2017–2025

Fiscal year ended December 31, 2025 · U.S. dollars

FDMT valuation Price multiples at each fiscal year-end price.

Price / sales
5.1
2025 · hover or tap a bar for each year
2020: 81.22021: 33.7 (−58.5%)2022: 229.6 (+580.8%)2023: 38.3 (−83.3%)2025: 5.1
20172025
Price / book+46.0%
0.9
2025 · hover or tap a bar for each year
2020: 4.32021: 1.9 (−55.8%)2022: 3.1 (+62.9%)2023: 2.6 (−17.1%)2024: 0.6 (−77.2%)2025: 0.9 (+46.0%)
20172025
Free cash flow yield+20.9 pts
−25.1%
2025 · hover or tap a bar for each year
2020: −4.7%2021: −12.9% (−8.2 pts)2022: −13.7% (−0.8 pts)2023: −9.9% (+3.8 pts)2024: −46.1% (−36.1 pts)2025: −25.1% (+20.9 pts)
20172025

FDMT valuation history

Fiscal year-endToday9-year median

FDMT returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

FDMT debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

FDMT cash returned to shareholders

DividendsBuybacksFree cash flow

FDMT price vs earnings per share

Share price at year-endEPS (right axis)

FDMT key metrics

2017–2025
4D Molecular Therapeutics, Inc. key metrics by fiscal year
202520242023202220212020201920182017
Valuation
Market capitalization$434.5M$300.5M$792.8M$718.5M$608.4M$1.11B———
Enterprise value$53.2M−$99.8M$519.2M$521.1M$377.1M$829.2M———
Price / sales5.1—38.3229.633.781.2———
Price / book0.90.62.63.11.94.3———
EV / sales0.6-2,697.425.1166.520.960.9———
Earnings yield−32.2%−53.5%−12.7%−14.1%−11.2%−5.1%———
Free cash flow yield−25.1%−46.1%−9.9%−13.7%−12.9%−4.7%———
Shareholder yield (dividends + buybacks)0.0%——0.1%0.0%25.1%———
Share price at fiscal year-end$7.50$5.57$20.26$22.21$21.94$41.45———
Per share
Revenue per share$1.47$0.00$0.53$0.10$0.65$0.51$0.26$1.13$0.39
Earnings per share−$2.42−$2.98−$2.58−$3.12−$2.46−$2.12−$1.86−$0.76−$0.76
Operating cash flow per share−$1.88−$2.49−$1.94−$2.68−$2.49−$1.91−$1.39−$1.30$0.56
Free cash flow per share−$1.88−$2.57−$2.01−$3.04−$2.82−$1.95−$1.51−$1.33$0.52
Cash per share$6.95$7.88$7.37$6.60$8.94$10.37$1.87$7.33$1.61
Book value per share$8.73$9.47$7.87$7.15$11.51$9.61−$2.75−$2.20−$1.32
Tangible book value per share$8.73$9.47$7.87$7.15$11.51$9.61−$2.75−$2.20−$1.32
Capex per share$0.01$0.07$0.07$0.36$0.33$0.04$0.12$0.03$0.04
Debt per share$0.37$0.46$0.37$0.50$0.59——$0.01$0.00
Shares outstanding57.9M53.9M39.1M32.4M27.7M26.7M26.5M12.5M14.8M
Change in shares outstanding+7.4%+37.9%+21.0%+16.7%+3.9%+0.7%+111.6%−15.6%—
Returns & profitability
Return on equity (ROE)−27.6%−39.3%−37.4%−36.7%−23.7%−61.8%———
Return on invested capital (ROIC)−107.4%−205.2%−261.6%−142.9%−167.1%————
Return on assets (ROA)−24.9%−35.7%−33.5%−32.9%−21.3%−32.7%−63.5%−15.4%−41.1%
Return on tangible assets−24.7%−28.7%−29.7%−38.6%−19.3%−19.7%−84.7%−9.8%−41.1%
Free cash flow margin−128.0%—−379.1%—−433.8%−381.3%−571.3%−117.9%132.4%
Financial health
Total debt$21.4M$24.6M$14.7M$16.1M$16.4M——$93,000$51,000
Cash & short-term investments$402.7M$424.9M$288.2M$213.6M$247.8M$276.7M$49.7M$91.8M$23.9M
Net debt−$381.2M−$400.3M−$273.6M−$197.4M−$231.3M−$276.7M−$49.7M−$91.7M−$23.8M
Debt / equity0.040.050.050.070.05————
Debt / assets0.040.040.040.060.05——0.000.00
Current ratio9.3914.9215.6514.0215.6916.884.0511.684.15
Quick ratio9.3914.9215.6514.3916.2116.884.0511.684.15
Interest coverage———-17.1-23.5-372.8———
Working capital$369.1M$405.8M$277.6M$204.8M$239.9M$265.9M$39.6M$86.0M$18.6M
Invested capital$124.4M$110.3M$34.3M$33.9M$87.8M−$20.3M−$122.6M−$119.3M−$43.4M
Tangible asset value$505.7M$510.6M$307.8M$231.3M$319.1M$256.4M−$73.0M−$27.6M−$19.6M
Net current asset value$352.1M$385.2M$264.5M$190.0M$221.9M$250.7M−$78.7M−$30.5M−$22.4M
Graham net-net per share$5.90$6.95$6.55$5.58$7.54$9.22−$3.05−$2.55−$1.54
Capital allocation
Share buybacks (net)$0——$468,000$0$278.1M$2.3M——
Capex / revenue0.6%10,232.4%13.4%368.7%50.5%7.3%45.8%2.9%9.9%
Capex / operating cash flow————————7.0%
Capex / depreciation0.070.560.482.973.020.693.190.590.92
Stock-based compensation / revenue25.8%70,583.8%94.9%547.2%76.5%36.6%50.7%9.7%4.4%
R&D / revenue229.7%381,889.2%468.5%2,564.8%340.2%389.6%627.8%130.0%234.4%
SG&A / revenue57.6%125,889.2%176.1%1,051.7%155.3%126.6%198.9%43.6%60.3%
Efficiency
Days sales outstanding———43.615.533.054.918.720.2
Days of inventory on hand———-672.2-1,027.7———0.0
Days payables outstanding372.110.212.9380.3395.912.112.714.112.4
Cash conversion cycle (days)———-1,009.0-1,408.120.942.24.67.9
Receivables turnover———8.3823.5311.056.6519.5618.04
Payables turnover0.9835.7728.400.960.9230.0428.7025.9729.51
Inventory turnover————————13,573,000.00
Asset turnover0.150.000.070.010.060.080.090.230.21
Average receivables———$373,500$766,500$1.2M$1.1M$722,500$321,000
Average payables$7.8M$4.0M$3.4M$4.0M$3.3M$1.8M$1.3M$707,000$460,000
Average inventory———−$7.1M−$8.5M———$1
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from FDMT's annual financial statements (latest annual report filed March 18, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

FDMT valuation and financial ratios

4D Molecular Therapeutics earned a return on equity of −27.6% and a return on invested capital of −107.4% in fiscal 2025. It ended the year with $21.4 million of debt and $402.7 million in cash and short-term investments, a net cash position of $381.2 million. The share count rose 290.5% from 14.8M to 57.9M over 8 years.

See the FDMT income statement, the FDMT chart for price history, or the FDMT stock overview for the latest quote and news.

FDMT key metrics FAQ

What is 4D Molecular Therapeutics's return on equity?

4D Molecular Therapeutics's return on equity (ROE) was −27.6% in fiscal 2025: net income of -$140.1 million on average shareholders' equity of $508.1 million.

What is 4D Molecular Therapeutics's ROIC?

4D Molecular Therapeutics's return on invested capital was −107.4% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does 4D Molecular Therapeutics have?

4D Molecular Therapeutics had total debt of $21.4 million at the end of fiscal 2025, a debt-to-equity ratio of 0.04 and more cash than debt.

What is 4D Molecular Therapeutics's free cash flow yield?

4D Molecular Therapeutics generated -$109.1 million of free cash flow in fiscal 2025, a free cash flow yield of −25.1% on its market value at year-end ($434.5 million).

What is 4D Molecular Therapeutics's current ratio?

4D Molecular Therapeutics's current ratio was 9.39 at the end of fiscal 2025: current assets were 9.39 times current liabilities.

Biotechnology key metrics