Personalis, Inc. (PSNL) Income Statement
PSNL 2025 at a glance
Fiscal year ended December 31, 2025 · U.S. dollarsPSNL revenue and net income
Where PSNL's revenue goes
2025Each bar shows an amount and its share of revenue. PSNL kept −116.7% of revenue as net income.
PSNL profit margins
PSNL growth rates
to 2025| 1 year | 3 years | 5 years | 10 years | |
|---|---|---|---|---|
| Revenue | −17.7% | +2.3% | −2.4% | — |
| Gross profit | −41.2% | +5.7% | −4.7% | — |
| Operating income | — | — | — | — |
| Net income | — | — | — | — |
| EPS (diluted) | — | — | — | — |
1-year change and average annual growth (CAGR) over 3, 5 and 10 fiscal years. "—" when a starting value was zero or negative.
PSNL quarterly EPS vs estimates
Personalis beat the analyst EPS estimate in 5 of the last 8 quarters. Next report: November 3, 2026 (estimate $-0.26).
PSNL income statement
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | $69.6M | $84.6M | $73.5M | $65.0M | $85.5M | $78.6M | $65.2M | $37.8M | $9.4M |
| Cost of revenue | $53.9M | $57.8M | $55.3M | $51.7M | $53.8M | $58.5M | $43.1M | $26.0M | $11.7M |
| Gross profit | $15.8M | $26.8M | $18.2M | $13.3M | $31.7M | $20.1M | $22.1M | $11.8M | −$2.3M |
| Research & development | $50.3M | $48.9M | $64.8M | $64.9M | $49.3M | $28.6M | $22.4M | $14.3M | $9.9M |
| Sales, general & admin | $53.6M | $46.2M | $49.7M | $64.0M | $47.7M | $33.7M | $22.1M | $11.3M | $9.9M |
| Total operating expenses | $103.8M | $95.1M | $114.5M | $128.9M | $97.0M | $62.3M | $44.5M | $25.6M | $19.8M |
| Operating income | −$88.1M | −$68.3M | −$96.3M | −$115.5M | −$65.4M | −$42.1M | −$22.4M | −$13.8M | −$22.2M |
| Interest income | $7.2M | $5.5M | $5.9M | $2.4M | $367,000 | $949,000 | $1.6M | $293,000 | $100,000 |
| Interest expense | $205,000 | $24,000 | $110,000 | $201,000 | $184,000 | $2,000 | $1.1M | $1.9M | $1.3M |
| Income before taxes | −$81.2M | −$81.3M | −$108.2M | −$113.3M | −$65.2M | −$41.2M | −$25.1M | −$19.9M | −$23.6M |
| Income taxes | $21,000 | $18,000 | $83,000 | $40,000 | $14,000 | $57,000 | $9,000 | $7,000 | $5,000 |
| Net income | −$81.3M | −$81.3M | −$108.3M | −$113.3M | −$65.2M | −$41.3M | −$25.1M | −$19.9M | −$23.6M |
| EBITDA | −$71.0M | −$70.3M | −$96.8M | −$104.6M | −$59.0M | −$35.5M | −$19.2M | −$14.9M | −$21.1M |
| EPS (diluted) | −$0.91 | −$1.37 | −$2.13 | −$2.48 | −$1.48 | −$1.19 | −$1.10 | −$0.91 | −$7.87 |
| Gross margin | 22.7% | 31.7% | 24.8% | 20.5% | 37.0% | 25.6% | 33.9% | 31.3% | −24.9% |
| Operating margin | −126.4% | −80.7% | −131.0% | −177.6% | −76.4% | −53.6% | −34.4% | −36.5% | −236.0% |
| Net margin | −116.7% | −96.1% | −147.4% | −174.2% | −76.3% | −52.5% | −38.5% | −52.6% | −251.2% |
| Jun '26 | Mar '26 | Dec '25 | Sep '25 | Jun '25 | Mar '25 | Dec '24 | Sep '24 | Jun '24 | Mar '24 | Dec '23 | Sep '23 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $22.4M | $15.5M | $17.3M | $14.5M | $17.2M | $20.6M | $16.8M | $25.7M | $22.6M | $19.5M | $19.7M | $18.2M |
| Cost of revenue | $17.6M | $15.2M | $15.4M | $12.6M | $12.4M | $13.4M | $12.2M | $17.0M | $14.5M | $14.0M | $14.5M | $14.8M |
| Gross profit | $4.7M | $281,000 | $1.9M | $1.9M | $4.8M | $7.2M | $4.5M | $8.7M | $8.0M | $5.5M | $5.2M | $3.5M |
| Research & development | $16.3M | $14.5M | $13.1M | $12.2M | $12.4M | $12.6M | $11.5M | $11.7M | $13.0M | $12.8M | $13.6M | $16.7M |
| Sales, general & admin | $22.0M | $17.9M | $14.1M | $13.0M | $14.2M | $12.3M | $11.2M | $11.4M | $12.0M | $11.6M | $11.5M | $12.0M |
| Total operating expenses | $38.3M | $32.4M | $27.2M | $25.2M | $26.6M | $24.9M | $22.7M | $23.1M | $24.9M | $24.4M | $29.2M | $34.3M |
| Operating income | −$33.6M | −$32.2M | −$25.3M | −$23.3M | −$21.8M | −$17.7M | −$18.1M | −$14.4M | −$16.9M | −$18.9M | −$24.0M | −$30.8M |
| Interest income | $2.0M | $2.2M | $1.6M | $1.7M | $1.9M | $2.0M | $1.6M | $1.4M | $1.1M | $1.4M | $1.5M | $1.7M |
| Interest expense | $37,000 | $47,000 | $65,000 | $64,000 | $48,000 | $28,000 | $1,000 | $7,000 | $9,000 | $9,000 | $9,000 | $15,000 |
| Income before taxes | −$31.7M | −$30.0M | −$23.8M | −$21.6M | −$20.1M | −$15.7M | −$16.4M | −$39.1M | −$12.8M | −$13.0M | −$26.6M | −$29.1M |
| Income taxes | $5,000 | $16,000 | $9,000 | $3,000 | $2,000 | $7,000 | $4,000 | $3,000 | $4,000 | $7,000 | $5,000 | $28,000 |
| Net income | −$31.7M | −$30.0M | −$23.8M | −$21.7M | −$20.1M | −$15.8M | −$16.4M | −$39.1M | −$12.8M | −$13.0M | −$26.6M | −$29.1M |
| EBITDA | −$29.2M | −$27.6M | −$21.3M | −$19.1M | −$17.5M | −$13.1M | −$13.9M | −$36.3M | −$10.0M | −$10.1M | −$23.7M | −$26.3M |
| EPS (diluted) | −$0.30 | −$0.29 | −$0.26 | −$0.24 | −$0.23 | −$0.18 | −$0.23 | −$0.64 | −$0.24 | −$0.26 | −$0.54 | −$0.48 |
| Gross margin | 21.2% | 1.8% | 11.0% | 13.2% | 27.6% | 35.0% | 27.1% | 34.0% | 35.6% | 28.1% | 26.5% | 19.1% |
| Operating margin | −150.2% | −207.9% | −145.7% | −160.7% | −126.7% | −85.9% | −107.8% | −55.9% | −74.8% | −96.7% | −121.8% | −168.8% |
| Net margin | −141.7% | −194.1% | −137.3% | −149.4% | −116.6% | −76.4% | −97.8% | −152.0% | −56.7% | −66.4% | −135.1% | −159.5% |
Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported in PSNL's financial statements (latest annual report filed February 26, 2026); data from EODHD. Sales, general & administrative expenses include sales and marketing.
PSNL financial results
In fiscal year 2025 (ended December 31, 2025), Personalis reported revenue of $69.6 million, down 17.7% from the year before. It had a net loss of $81.3 million, a net profit margin of −116.7%. Diluted earnings per share came to −$0.91. Over five years revenue grew at an average rate of −2.4% a year.
See the PSNL stock overview for the latest quote and news, or the PSNL chart for price history and technical indicators.
PSNL income statement FAQ
What is Personalis's annual revenue?
Personalis reported total revenue of $69.6 million for fiscal year 2025, which ended on December 31, 2025. That was down 17.7% from $84.6 million the previous year.
Is Personalis profitable?
No. Personalis reported a net loss of $81.3 million in fiscal 2025, a net profit margin of −116.7%; its operating margin was −126.4%.
What is Personalis's gross margin?
Personalis's gross margin was 22.7% in fiscal 2025: for every $100 of revenue, Personalis kept $23 after the direct cost of its products and services.
How much does Personalis spend on research and development?
Personalis spent $50.3 million on research and development in fiscal 2025, 72.2% of revenue.
How fast is Personalis growing?
Revenue grew −2.4% a year on average over the last five fiscal years, from $78.6 million to $69.6 million.
What are Personalis's earnings per share?
Personalis earned $-0.91 per diluted share in fiscal 2025, compared with $-1.37 a year earlier.
When will Personalis report its next earnings?
Personalis is expected to report results for the quarter ending September 30, 2026 on November 3, 2026 after the market closes.
When does Personalis's fiscal year end?
Personalis's fiscal year ends in December. The latest annual report covers the year ended December 31, 2025 and was filed on February 26, 2026.