Palisade Bio, Inc. (PALI) Cash Flow Statement

NASDAQ: PALIOperating cash, capex, free cash flow and buybacks.

Where PALI’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$10.8M
Capital expenditures
$0
Free cash flow
−$10.8M
Returned to shareholders
—
Change in cash
$123.6M
cash at year-end $133.4M
Shares issued: $128.2MShares issued$128.2MOther financing: $6.5MOther financing$6.5MCash used in operations: $10.8MCash used in operations$10.8M · 8%Added to cash: $123.6MAdded to cash$123.6M · 92%Debt repayment: $320,000Debt repayment$320,000 · 0%$134.8M
Cash from operations
−$10.8M
Net borrowing (repayment)
−$320,000
Shares issued
+$128.2M
Other financing
+$6.5M
Change in cash
$123.6M

Drawn to scale: where the cash came from and how it was used. Hover for values.

PALI operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

PALI cash flow trends, 2016–2025

Palisade Bio, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$15.6M2016−$10.8M2025—
Capital expenditures$161,1142016$02025−100.0%
Free cash flow−$15.8M2016−$10.8M2025—
Free cash flow margin−97,114.5%2016−4,454.8%2023+92,659.7 pts
Stock-based compensation$3.4M2016$4.0M2025+1.5%/yr
Share buybacks (net)$02016$02025—
Capex / revenue991.7%20161.6%2023−990.1 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

PALI cash flow by activity

OperatingInvestingFinancingChange in cash

PALI net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

PALI cash flow statement

Palisade Bio, Inc. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$16.8M−$14.4M−$12.3M−$14.3M−$26.6M−$10.3M−$8.4M−$4.9M−$15.7M−$21.1M
Depreciation & amortization$3,000$3,000$4,000$3,000$2,000$3,000$143,859$185,803$289,208$337,508
Stock-based compensation$4.0M$652,000$624,000$1.0M$1.9M$2.0M$3.3M$1.1M$1.8M$3.4M
Change in working capital$1.6M$1.4M$400,000$1.2M−$4.8M$2.4M$208,285−$336,881−$2.2M$1.5M
Other non-cash items$337,000$199,000$139,000−$1.4M$14.7M$1.1M−$2.6M−$3.7M$2.3M$164,063
Cash from operating activities−$10.8M−$12.2M−$11.1M−$13.4M−$14.8M−$4.8M−$7.3M−$7.7M−$13.4M−$15.6M
Investing activities
Capital expenditures$0$0−$4,000−$10,000$0−$6,000−$6,000−$1,714−$94,046−$161,114
Investments (net)—$0−$4,000−$10,000−$54,000−$6,000————
Acquisitions & other investing——$4,000$10,000$0$6,000$3.9M$5.0M$0$2.5M
Cash from investing activities——−$4,000−$10,000−$54,000−$6,000$3.9M$5.0M−$94,046$2.4M
Financing activities
Dividends paid————−$99,000—————
Share repurchases & issuance (net)$19,000$11,000$17,000—−$99,000$14.7M$6.6M$1.8M$8.7M$28.1M
Net borrowing (repayment)−$320,000−$426,000−$391,000−$790,000−$183,000$2.0M−$220,000$1.4M——
Shares issued$128.2M$8.4M$9.4M$14.4M$25.1M$1.2M$0$0$0$0
Other financing$6.5M$1.6M$2.1M$1.6M−$119,000−$16.0M$256,425−$1.4M−$3.7M−$4.4M
Cash from financing activities$134.4M$9.6M$11.2M$15.3M$24.6M$1.9M$6.6M$1.8M$5.0M$23.7M
Summary
Net change in cash$123.6M−$2.6M$49,000$1.9M$9.8M−$2.9M−$672,193−$887,830−$8.5M$10.5M
Cash at end of period$133.4M$9.8M$12.5M$12.4M$10.5M$739,000$5.1M$5.8M$6.7M$15.2M
Free cash flow−$10.8M−$12.2M−$11.1M−$13.4M−$14.8M−$4.8M−$7.3M−$7.7M−$13.5M−$15.8M
Free cash flow margin——−4,454.8%−5,348.0%—−35,310.7%−47,133.2%−2,959.3%−5,196.2%−97,114.5%
Capex / revenue——1.6%4.0%—44.4%39.0%0.7%36.2%991.7%

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

PALI cash generation

In fiscal 2025 (ended December 31, 2025), Palisade Bio generated -$10.8 million of cash from operations and spent $0 on capital expenditures, leaving free cash flow of -$10.8 million. Cash and equivalents rose by $123.6 million over the year.

Related: PALI income statement, PALI balance sheet. See the PALI stock overview for the latest quote and news.

PALI cash flow FAQ

What is Palisade Bio's free cash flow?

Palisade Bio's free cash flow was -$10.8 million in fiscal 2025: -$10.8 million of operating cash flow minus $0 of capital expenditures It was -$12.2 million a year earlier..

How much cash does Palisade Bio generate from operations?

Palisade Bio generated -$10.8 million of cash from operating activities in fiscal 2025.

Biotechnology: cash flow