Schrödinger, Inc. (SDGR) Key Metrics

NASDAQ: SDGRValuation, returns, debt and efficiency ratios over 9 years.

SDGR valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$1.69B
Enterprise value
$1.88B
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
6.5
10-yr median 9.9
Price / book
6.6
10-yr median 4.0
EV / EBITDA
—
Dividend yield
—
Beta
1.62

SDGR key metrics, 2017–2025

Fiscal year ended December 31, 2025 · U.S. dollars

SDGR valuation Price multiples at each fiscal year-end price.

Price / sales−24.0%
5.1
2025 · hover or tap a bar for each year
2020: 44.02021: 17.8 (−59.5%)2022: 7.4 (−58.8%)2023: 12.4 (+68.5%)2024: 6.8 (−45.5%)2025: 5.1 (−24.0%)
20172025
Price / book+8.4%
3.6
2025 · hover or tap a bar for each year
2020: 7.62021: 4.4 (−42.0%)2022: 3.0 (−32.7%)2023: 4.9 (+64.8%)2024: 3.3 (−32.0%)2025: 3.6 (+8.4%)
20172025
Price / free cash flow
105.4
2025 · hover or tap a bar for each year
2020: 334.32025: 105.4
20172025
Free cash flow yield+12.7 pts
0.9%
2025 · hover or tap a bar for each year
2020: 0.3%2021: −3.2% (−3.5 pts)2022: −9.6% (−6.4 pts)2023: −5.6% (+4.0 pts)2024: −11.7% (−6.2 pts)2025: 0.9% (+12.7 pts)
20172025

SDGR valuation history

Fiscal year-endToday9-year median

SDGR returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

SDGR debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

SDGR price vs earnings per share

Share price at year-endEPS (right axis)

SDGR key metrics

2017–2025
Schrödinger, Inc. key metrics by fiscal year
202520242023202220212020201920182017
Valuation
Market capitalization$1.31B$1.40B$2.68B$1.33B$2.46B$4.75B———
Enterprise value$1.03B$1.17B$2.35B$995.6M$1.96B$4.12B———
P/E ratio——65.9——————
Price / sales5.16.812.47.417.844.0———
Price / book3.63.34.93.04.47.6———
Price / free cash flow105.4————334.3———
Price / operating cash flow94.5————283.6———
EV / sales4.05.610.85.514.238.1———
EV / EBITDA——48.5——————
EV / free cash flow82.4————289.9———
Earnings yield−7.9%−13.3%1.5%−11.2%−4.1%−0.5%———
Free cash flow yield0.9%−11.7%−5.6%−9.6%−3.2%0.3%———
Shareholder yield (dividends + buybacks)————0.0%0.0%———
Share price at fiscal year-end$17.88$19.29$35.80$18.69$34.83$79.18———
Per share
Revenue per share$3.48$2.86$2.89$2.54$1.95$1.80$1.35$1.37—
Earnings per share−$1.41−$2.57$0.54−$2.10−$1.42−$0.41−$0.39−$0.59—
Operating cash flow per share$0.19−$2.17−$1.82−$1.68−$1.00$0.28−$0.41−$0.49—
Free cash flow per share$0.17−$2.27−$2.00−$1.79−$1.10$0.24−$0.44−$0.60—
Cash per share$5.38$4.85$6.17$6.34$8.17$10.71$1.36$1.73—
Book value per share$4.96$5.80$7.32$6.29$7.89$10.40−$1.48−$1.48—
Tangible book value per share$4.89$5.73$7.19$6.22$7.89$10.40−$1.48−$1.48—
Capex per share$0.02$0.10$0.18$0.11$0.10$0.04$0.03$0.11—
Debt per share$1.49$1.62$1.71$1.64$1.13$0.20$0.23——
Shares outstanding73.4M72.7M75.0M71.2M70.6M60.0M63.3M48.5M—
Change in shares outstanding+1.1%−3.1%+5.4%+0.8%+17.6%−5.1%+30.5%——
Returns & profitability
Return on equity (ROE)−26.3%−38.6%8.2%−29.7%−17.0%−9.2%———
Return on invested capital (ROIC)−99.5%−82.6%−103.1%−133.5%−328.8%————
Return on assets (ROA)−13.3%−23.0%5.5%−20.6%−13.4%−5.4%−17.8%−31.8%−30.0%
Return on tangible assets−14.3%−22.9%5.1%−21.8%−13.3%−3.3%−15.8%−23.5%−30.0%
Free cash flow margin4.9%−79.3%−69.3%−70.6%−56.4%13.2%−32.6%−43.5%−34.1%
Income quality (OCF / net income)——−3.36——————
Financial health
Total debt$109.2M$117.8M$127.9M$116.5M$79.9M$11.8M$14.5M——
Cash & short-term investments$395.5M$352.1M$463.0M$451.1M$576.5M$642.7M$85.8M$84.1M$36.3M
Net debt−$286.2M−$234.3M−$335.1M−$334.6M−$496.6M−$630.9M−$71.4M−$84.1M−$36.3M
Debt / equity0.300.280.230.260.140.02———
Debt / assets0.150.140.160.170.110.020.09——
Net debt / EBITDA——−6.91——————
Current ratio2.753.314.254.916.859.332.633.882.70
Quick ratio2.753.314.255.036.959.382.633.882.70
Interest coverage————-4.9-0.9-1.6——
Working capital$330.1M$443.2M$434.1M$425.2M$533.8M$609.8M$73.5M$77.7M$30.2M
Invested capital$77.8M$187.2M$213.4M$113.3M$60.5M−$6.9M−$164.7M−$155.6M−$81.7M
Tangible asset value$359.3M$416.7M$539.0M$442.5M$557.1M$624.0M−$93.3M−$71.6M−$45.4M
Net current asset value$157.2M$233.2M$313.4M$293.3M$425.7M$560.7M−$130.1M−$87.6M−$55.3M
Graham number——$9.45——————
Graham net-net per share$1.52$1.95$3.67$3.59$5.71$9.08−$2.27−$1.95—
Capital allocation
Share buybacks (net)————$0$0$0$0$0
Dividends + buybacks / free cash flow—————0.0%———
Capex / revenue0.6%3.5%6.2%4.4%5.2%2.3%2.1%7.9%6.6%
Capex / operating cash flow10.4%————15.1%———
Capex / depreciation0.241.192.411.842.520.690.501.822.20
Stock-based compensation / revenue16.8%24.0%22.1%21.9%19.2%9.8%2.6%2.0%1.6%
R&D / revenue67.7%97.2%83.9%69.8%65.9%59.9%46.1%51.8%49.7%
SG&A / revenue53.3%67.3%62.9%67.1%62.5%55.2%56.6%54.6%55.9%
Efficiency
Days sales outstanding256.6302.9133.3110.6100.5103.293.476.164.0
Days of inventory on hand———-50.1-32.2-16.20.0——
Days payables outstanding35.666.563.140.141.648.831.533.737.0
Cash conversion cycle (days)220.9236.470.120.426.738.261.842.327.0
Receivables turnover1.421.212.743.303.633.543.914.805.71
Payables turnover10.245.495.789.118.787.4911.5810.829.87
Inventory turnover——————36,450,000.00——
Asset turnover0.330.260.290.250.180.240.620.750.96
Average receivables$179.9M$172.2M$79.1M$54.8M$38.0M$30.6M$21.9M$13.9M$9.8M
Average payables$11.1M$13.7M$13.1M$8.8M$8.2M$6.0M$3.1M$2.2M$1.6M
Average inventory———−$11.0M−$6.4M−$2.0M$1——
Intangibles / total assets0.7%0.6%1.2%0.8%0.0%0.0%0.0%0.0%0.1%

Computed from SDGR's annual financial statements (latest annual report filed February 25, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

SDGR valuation and financial ratios

Schrödinger earned a return on equity of −26.3% and a return on invested capital of −99.5% in fiscal 2025. It ended the year with $109.2 million of debt and $395.5 million in cash and short-term investments, a net cash position of $286.2 million.

See the SDGR income statement, the SDGR chart for price history, or the SDGR stock overview for the latest quote and news.

SDGR key metrics FAQ

What is Schrödinger's return on equity?

Schrödinger's return on equity (ROE) was −26.3% in fiscal 2025: net income of -$103.3 million on average shareholders' equity of $392.7 million.

What is Schrödinger's ROIC?

Schrödinger's return on invested capital was −99.5% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Schrödinger have?

Schrödinger had total debt of $109.2 million at the end of fiscal 2025, a debt-to-equity ratio of 0.30 and more cash than debt.

What is Schrödinger's free cash flow yield?

Schrödinger generated $12.5 million of free cash flow in fiscal 2025, a free cash flow yield of 0.9% on its market value at year-end ($1.3 billion).

What is Schrödinger's current ratio?

Schrödinger's current ratio was 2.75 at the end of fiscal 2025: current assets were 2.75 times current liabilities.

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