Edgewise Therapeutics, Inc. (EWTX) Key Metrics

NASDAQ: EWTXValuation, returns, debt and efficiency ratios over 7 years.

EWTX valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$4.04B
Enterprise value
$4.00B
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
—
Price / book
9.9
10-yr median 2.8
EV / EBITDA
—
Dividend yield
—
Beta
0.35

EWTX key metrics, 2019–2025

Fiscal year ended December 31, 2025 · U.S. dollars

EWTX valuation Price multiples at each fiscal year-end price.

Price / book−9.0%
4.9
2025 · hover or tap a bar for each year
2021: 2.82022: 1.4 (−49.9%)2023: 2.2 (+58.2%)2024: 5.4 (+145.7%)2025: 4.9 (−9.0%)
20192025
Free cash flow yield−1.2 pts
−5.6%
2025 · hover or tap a bar for each year
2021: −4.5%2022: −12.1% (−7.6 pts)2023: −14.0% (−1.9 pts)2024: −4.5% (+9.5 pts)2025: −5.6% (−1.2 pts)
20192025

EWTX valuation history

Fiscal year-endToday7-year median

EWTX returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

EWTX debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

EWTX price vs earnings per share

Share price at year-endEPS (right axis)

EWTX key metrics

2019–2025
Edgewise Therapeutics, Inc. key metrics by fiscal year
2025202420232022202120202019
Valuation
Market capitalization$2.55B$2.47B$697.1M$479.1M$756.4M——
Enterprise value$2.03B$2.00B$384.2M$131.6M$475.6M——
Price / book4.95.42.21.42.8——
Earnings yield−6.6%−5.4%−14.4%−3.2%−5.6%——
Free cash flow yield−5.6%−4.5%−14.0%−12.1%−4.5%——
Shareholder yield (dividends + buybacks)———0.0%0.0%——
Share price at fiscal year-end$24.82$26.70$10.94$8.94$15.28——
Per share
Revenue per share$0.00$0.00$0.00$0.00$0.00$0.00$0.00
Earnings per share−$1.63−$1.45−$1.57−$0.29−$0.85−$0.35−$0.19
Operating cash flow per share−$1.40−$1.18−$1.44−$0.98−$0.68−$0.30−$0.19
Free cash flow per share−$1.40−$1.19−$1.53−$1.09−$0.69−$0.30−$0.19
Cash per share$5.15$5.09$5.00$6.57$5.67$2.62$0.48
Book value per share$5.07$4.97$5.00$6.47$5.54−$0.68−$0.34
Tangible book value per share$5.07$4.97$5.00$6.47$5.54−$0.68−$0.34
Capex per share$0.00$0.01$0.09$0.10$0.01$0.00$0.00
Debt per share$0.04$0.05$0.08$0.08—$3.26$0.82
Shares outstanding102.9M92.4M63.7M53.6M49.5M49.2M49.2M
Change in shares outstanding+11.4%+45.0%+18.9%+8.3%+0.6%0.0%—
Returns & profitability
Return on equity (ROE)−34.2%−34.4%−30.1%−5.0%−35.0%——
Return on assets (ROA)−32.3%−32.4%−28.3%−4.7%−20.2%−21.9%−38.7%
Return on tangible assets−30.4%−27.5%−29.5%−4.2%−14.8%−13.0%−38.7%
Financial health
Total debt$4.0M$4.7M$5.4M$4.4M—$160.2M$40.3M
Cash & short-term investments$530.1M$470.2M$318.4M$351.9M$280.8M$129.1M$23.7M
Net debt−$526.1M−$465.4M−$313.0M−$347.5M−$280.8M$31.1M$16.6M
Debt / equity0.010.010.020.01———
Debt / assets0.010.010.020.01—1.221.64
Current ratio19.8519.9319.5021.5326.9729.8621.24
Quick ratio19.8519.9319.5021.5326.9729.8621.24
Interest coverage———-5.5-158.9-249.2—
Working capital$516.0M$451.6M$310.2M$340.4M$273.3M$125.3M$22.9M
Invested capital−$3.9M−$6.2M$5.9M−$823,000−$6.4M−$2.3M−$244,000
Tangible asset value$522.3M$459.2M$318.8M$346.7M$274.4M−$33.4M−$16.9M
Net current asset value$513.0M$447.9M$305.8M$336.6M$272.9M−$34.9M−$17.4M
Graham net-net per share$4.86$4.79$4.66$6.19$5.46−$0.72−$0.36
Capital allocation
Share buybacks (net)———$0$0——
Capex / depreciation0.110.573.3210.312.461.101.46
Efficiency
Days payables outstanding933.0765.41,067.43,374.63,638.62,216.61,979.3
Receivables turnover———0.000.00——
Payables turnover0.390.480.340.110.100.160.18
Asset turnover0.000.000.000.000.000.000.00
Average receivables———$399,500$548,000——
Average payables$5.8M$4.8M$5.1M$5.0M$2.7M$1.1M$667,000
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from EWTX's annual financial statements (latest annual report filed February 26, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

EWTX valuation and financial ratios

Edgewise Therapeutics earned a return on equity of −34.2% in fiscal 2025. It ended the year with $4.0 million of debt and $530.1 million in cash and short-term investments, a net cash position of $526.1 million. The share count rose 109.1% from 49.2M to 102.9M over 6 years.

See the EWTX income statement, the EWTX chart for price history, or the EWTX stock overview for the latest quote and news.

EWTX key metrics FAQ

What is Edgewise Therapeutics's return on equity?

Edgewise Therapeutics's return on equity (ROE) was −34.2% in fiscal 2025: net income of -$167.8 million on average shareholders' equity of $490.7 million.

How much debt does Edgewise Therapeutics have?

Edgewise Therapeutics had total debt of $4.0 million at the end of fiscal 2025, a debt-to-equity ratio of 0.01 and more cash than debt.

What is Edgewise Therapeutics's free cash flow yield?

Edgewise Therapeutics generated -$143.8 million of free cash flow in fiscal 2025, a free cash flow yield of −5.6% on its market value at year-end ($2.6 billion).

What is Edgewise Therapeutics's current ratio?

Edgewise Therapeutics's current ratio was 19.85 at the end of fiscal 2025: current assets were 19.85 times current liabilities.

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