aTyr Pharma, Inc. (ATYR) Cash Flow Statement

NASDAQ: ATYROperating cash, capex, free cash flow and buybacks.

Where ATYR’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$62.0M
Capital expenditures
$77,000
40.5% of revenue
Free cash flow
−$62.1M
−32,664.7% margin
Returned to shareholders
—
Change in cash
−$1.0M
cash at year-end $13.0M
Shares issued: $66.4MShares issued$66.4MDrawn from cash: $1.0MDrawn from cash$1.0MCash used in operations: $62.0MCash used in operations$62.0M · 92%Investments (net): $5.0MInvestments (net)$5.0M · 7%Debt repayment, Capital expenditures: $616,000Other uses$616,000 · 1%$67.6M
Cash from operations
−$62.0M
Investments (net)
−$5.0M
Net borrowing (repayment)
−$539,000
Shares issued
+$66.4M
Change in cash
−$1.0M

Drawn to scale: where the cash came from and how it was used. Hover for values.

ATYR operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

ATYR cash flow trends, 2016–2025

aTyr Pharma, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$52.9M2016−$62.0M2025—
Capital expenditures$600,0002016$77,0002025−20.4%/yr
Free cash flow−$53.5M2016−$62.1M2025—
Free cash flow margin−4,761.1%2019−32,664.7%2025−27,903.6 pts
Stock-based compensation$1.8M2019$5.0M2025+18.7%/yr
Capex / revenue18.7%201940.5%2025+21.8 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

ATYR cash flow by activity

OperatingInvestingFinancingChange in cash

ATYR net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

ATYR cash flow statement

aTyr Pharma, Inc. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$74.1M−$64.0M−$50.4M−$45.3M−$33.8M−$16.2M−$23.8M−$34.5M−$48.2M−$57.9M
Depreciation & amortization$1.6M$1.5M$2.7M$1.7M$1.3M$1.3M$1.4M$746,000$713,000$900,000
Stock-based compensation$5.0M$3.0M$2.6M$2.2M$1.6M$1.5M$1.8M———
Change in working capital$7.5M−$6.9M$15.0M−$833,000−$2.6M−$2.3M$206,000−$1.4M−$1.7M−$1.4M
Other non-cash items−$1.9M−$2.7M−$3.2M$441,000$363,000$453,000$395,000$4.2M$6.9M$5.4M
Cash from operating activities−$62.0M−$69.1M−$33.2M−$41.9M−$33.1M−$15.3M−$20.0M−$31.1M−$42.4M−$52.9M
Investing activities
Capital expenditures−$77,000−$65,000−$4.2M−$1.6M−$192,000−$202,000−$79,000−$594,000−$1.3M−$600,000
Investments (net)−$5.0M$17.2M−$20.1M$47.2M−$91.6M$6.9M————
Acquisitions & other investing$12,000$65,000$4.2M$1.6M$192,000$202,000$5.0M$37.8M−$26.3M$34.1M
Cash from investing activities−$5.1M$17.2M−$20.1M$47.2M−$91.6M$6.9M$4.9M$37.2M−$27.6M$33.5M
Financing activities
Net borrowing (repayment)−$539,000−$497,000−$394,000−$66,000$0—————
Shares issued$66.4M$40.3M$66.5M$5.5M$110.0M$25.2M$0$0$0$0
Other financing$127,000$100,000$105,000$45,000$73,000−$9.1M$1.3M−$4.2M$52.7M$4.7M
Cash from financing activities$66.0M$39.9M$66.2M$5.5M$110.0M$16.1M$1.3M−$4.2M$52.7M$4.7M
Summary
Net change in cash−$1.0M−$12.0M$12.9M$10.8M−$14.6M$7.7M−$13.8M$1.9M−$17.3M−$14.6M
Cash at end of period$13.0M$14.0M$26.0M$13.1M$2.3M$17.0M$9.2M$23.0M$21.1M$38.4M
Free cash flow−$62.1M−$69.2M−$37.4M−$43.5M−$33.3M−$15.5M−$20.1M−$31.7M−$43.7M−$53.5M
Free cash flow margin−32,664.7%−29,440.0%−10,605.1%−419.1%—−148.3%−4,761.1%———
Capex / revenue40.5%27.7%1,194.1%15.8%—1.9%18.7%———

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

ATYR cash generation

In fiscal 2025 (ended December 31, 2025), aTyr Pharma generated -$62.0 million of cash from operations and spent $0.1 million on capital expenditures, leaving free cash flow of -$62.1 million, −32,664.7% of revenue. Cash and equivalents fell by $1.0 million over the year.

Related: ATYR income statement, ATYR balance sheet. See the ATYR stock overview for the latest quote and news.

ATYR cash flow FAQ

What is aTyr Pharma's free cash flow?

aTyr Pharma's free cash flow was -$62.1 million in fiscal 2025: -$62.0 million of operating cash flow minus $0.1 million of capital expenditures It was -$69.2 million a year earlier..

How much cash does aTyr Pharma generate from operations?

aTyr Pharma generated -$62.0 million of cash from operating activities in fiscal 2025.

How much does aTyr Pharma spend on capital expenditures?

aTyr Pharma spent $0.1 million on capital expenditures in fiscal 2025, 40.5% of revenue, compared with $0.1 million the year before.

Biotechnology: cash flow