Sera Prognostics, Inc. (SERA) Income Statement

NASDAQ: SERARevenue, profits, margins and EPS over 7 years.

SERA 2025 at a glance

Fiscal year ended December 31, 2025 · U.S. dollars
Revenue+5.2%
$81,000
2025 · hover or tap a bar for each year
2019: $36,0002020: $25,000 (−30.6%)2021: $82,000 (+228.0%)2022: $268,000 (+226.8%)2023: $306,000 (+14.2%)2024: $77,000 (−74.8%)2025: $81,000 (+5.2%)
20192025
Gross profit
−$83,000
2025 · hover or tap a bar for each year
2019: $18,0002020: $14,000 (−22.2%)2021: $45,000 (+221.4%)2022: $75,000 (+66.7%)2023: $96,000 (+28.0%)2024: −$5,000 (−105.2%)2025: −$83,000
20192025
Operating income
−$36.5M
2025 · hover or tap a bar for each year
2019: −$16.6M2020: −$18.0M2021: −$35.4M2022: −$45.7M2023: −$39.8M2024: −$36.6M2025: −$36.5M
20192025
Net income
−$31.9M
2025 · hover or tap a bar for each year
2019: −$16.5M2020: −$19.8M2021: −$35.0M2022: −$44.2M2023: −$36.2M2024: −$32.9M2025: −$31.9M
20192025
EPS (diluted)
−$0.68
2025 · hover or tap a bar for each year
2019: −$1.482020: −$1.712021: −$4.142022: −$1.432023: −$1.162024: −$0.992025: −$0.68
20192025
Net profit margin+3,307.4 pts
−39,417.3%
2025 · hover or tap a point for each year
2019: −45,891.7%2020: −79,392.0% (−33,500.3 pts)2021: −42,693.9% (+36,698.1 pts)2022: −16,487.3% (+26,206.6 pts)2023: −11,843.8% (+4,643.5 pts)2024: −42,724.7% (−30,880.9 pts)2025: −39,417.3% (+3,307.4 pts)
20192025

SERA revenue and net income

RevenueNet incomeNet margin (right axis)

Where SERA's revenue goes

2025
Revenue
$81,000100.0%
Cost of revenue
−$164,000−202.5%
Gross profit
−$83,000−102.5%
Research & development
−$13.2M−16,260.5%
Sales, general & admin
−$23.2M−28,703.7%
Operating income
−$36.5M−45,066.7%
Interest & other income
$4.6M5,649.4%
Net income
−$31.9M−39,417.3%

Each bar shows an amount and its share of revenue. SERA kept −39,417.3% of revenue as net income.

SERA profit margins

GrossOperatingNet

SERA growth rates

to 2025
1 year3 years5 years10 years
Revenue+5.2%−32.9%+26.5%—
Gross profit————
Operating income————
Net income————
EPS (diluted)————

1-year change and average annual growth (CAGR) over 3, 5 and 10 fiscal years. "—" when a starting value was zero or negative.

SERA quarterly EPS vs estimates

Reported EPSAnalyst estimate

Sera Prognostics beat the analyst EPS estimate in 5 of the last 8 quarters. Next report: November 12, 2026 (estimate $-0.14).

SERA income statement

Sera Prognostics, Inc. annual income statement
2025202420232022202120202019
Revenue$81,000$77,000$306,000$268,000$82,000$25,000$36,000
Cost of revenue$164,000$82,000$210,000$193,000$37,000$11,000$18,000
Gross profit−$83,000−$5,000$96,000$75,000$45,000$14,000$18,000
Research & development$13.2M$14.7M$15.2M$14.2M$11.0M$7.8M$9.4M
Sales, general & admin$23.2M$21.9M$24.7M$31.5M$24.4M$10.2M$7.2M
Total operating expenses$36.4M$36.6M$39.9M$45.7M$35.4M$18.0M$16.6M
Operating income−$36.5M−$36.6M−$39.8M−$45.7M−$35.4M−$18.0M−$16.6M
Interest income$4.3M$2.7M$1.6M$456,000$145,000$42,000$64,000
Interest expense$9,000$28,000$55,000$61,000$746,000$1.8M$2.0M
Income before taxes−$31.9M−$32.9M−$36.2M−$44.2M−$35.0M−$19.8M−$16.5M
Income taxes——$732,105$61,000$1.2M$1.8M$3.9M
Net income−$31.9M−$32.9M−$36.2M−$44.2M−$35.0M−$19.8M−$16.5M
EBITDA−$31.0M−$32.0M−$35.3M−$43.4M−$33.6M−$17.1M−$13.6M
EPS (diluted)−$0.68−$0.99−$1.16−$1.43−$4.14−$1.71−$1.48
Gross margin−102.5%−6.5%31.4%28.0%54.9%56.0%50.0%
Operating margin−45,066.7%−47,577.9%−13,013.4%−17,034.3%−43,164.6%−71,884.0%−46,044.4%
Net margin−39,417.3%−42,724.7%−11,843.8%−16,487.3%−42,693.9%−79,392.0%−45,891.7%

Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported in SERA's financial statements (latest annual report filed March 18, 2026); data from EODHD. Sales, general & administrative expenses include sales and marketing.

SERA financial results

In fiscal year 2025 (ended December 31, 2025), Sera Prognostics reported revenue of $0.1 million, up 5.2% from the year before. It had a net loss of $31.9 million, a net profit margin of −39,417.3%. Diluted earnings per share came to −$0.68. Over five years revenue grew at an average rate of 26.5% a year.

See the SERA stock overview for the latest quote and news, or the SERA chart for price history and technical indicators.

SERA income statement FAQ

What is Sera Prognostics's annual revenue?

Sera Prognostics reported total revenue of $0.1 million for fiscal year 2025, which ended on December 31, 2025. That was up 5.2% from $0.1 million the previous year.

Is Sera Prognostics profitable?

No. Sera Prognostics reported a net loss of $31.9 million in fiscal 2025, a net profit margin of −39,417.3%; its operating margin was −45,066.7%.

What is Sera Prognostics's gross margin?

Sera Prognostics's gross margin was −102.5% in fiscal 2025: for every $100 of revenue, Sera Prognostics kept $-102 after the direct cost of its products and services.

How much does Sera Prognostics spend on research and development?

Sera Prognostics spent $13.2 million on research and development in fiscal 2025, 16,260.5% of revenue.

How fast is Sera Prognostics growing?

Revenue grew 26.5% a year on average over the last five fiscal years, from $0.0 million to $0.1 million.

What are Sera Prognostics's earnings per share?

Sera Prognostics earned $-0.68 per diluted share in fiscal 2025, compared with $-0.99 a year earlier.

When will Sera Prognostics report its next earnings?

Sera Prognostics is expected to report results for the quarter ending September 30, 2026 on November 12, 2026.

When does Sera Prognostics's fiscal year end?

Sera Prognostics's fiscal year ends in December. The latest annual report covers the year ended December 31, 2025 and was filed on March 18, 2026.

Medical Devices income statements